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EC Explorer

EC Details
EC number
Accepted name
DNA topoisomerase
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining
Other name(s)
type I DNA topoisomerase, untwisting enzyme, relaxing enzyme, nicking-closing enzyme, swivelase, ω-protein, deoxyribonucleate topoisomerase, topoisomerase
Systematic name
DNA topoisomerase
CAS registry number
These enzymes bring about the conversion of one topological isomer of DNA into another, e.g., the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences, cf. EC DNA topoisomerase (ATP-hydrolysing).
created 1984, deleted 2018