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EC 6.3.3.7 Details
EC number
6.3.3.7
Accepted name
Ni-sirohydrochlorin a,c-diamide reductive cyclase
Reaction
ATP + Ni-sirohydrochlorin a,c-diamide + 3 reduced electron acceptor + H2O = ADP + phosphate + 15,173-seco-F430-173-acid + 3 electron acceptor
Other name(s)
cfbC (gene name),
cfbD (gene name)
Systematic name
Ni-sirohydrochlorin a,c-diamide reductive cyclo-ligase (ADP-forming)
Comment
The enzyme, studied from the methanogenic archaeon Methanosarcina acetivorans, participates in the biosynthesis of the nickel-containing tetrapyrrole cofactor coenzyme F430, which is required by EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase.
History
created 2017
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