EC Explorer

[browse EC tree] - [search]

EC 6.3.3.3 Details

show Brenda entry

EC number

6.3.3.3

Accepted name

dethiobiotin synthase

Reaction

ATP + 7,8-diaminononanoate + CO₂ = ADP + phosphate + dethiobiotin

Other name(s)

desthiobiotin synthase

Systematic name

7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming)

CAS registry number

37259-75-9

Comment

CTP has half the activity of ATP.

History

created 1976

EC Tree

1 Oxidoreductases

5.1 Racemases and epimerases

5.2 cis-trans-Isomerases

5.3 Intramolecular oxidoreductases

5.4 Intramolecular transferases

5.5 Intramolecular lyases

5.6 Isomerases altering macromolecular conformation

5.99 Other isomerases

6.1 Forming carbon-oxygen bonds

6.1.1 Ligases forming aminoacyl-tRNA and related compounds

6.1.2 acid-alcohol ligases (ester synthases)

6.1.3 Cyclo-ligases

6.1.3.1 olefin β-lactone synthetase

6.2 Forming carbon-sulfur bonds

6.3 Forming carbon-nitrogen bonds

6.3.1 Acid—ammonia (or amine) ligases (amide synthases)

6.3.2 Acid—amino-acid ligases (peptide synthases)

6.3.3 Cyclo-ligases

6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase

6.3.3.2 5-formyltetrahydrofolate cyclo-ligase

6.3.3.3 dethiobiotin synthase

6.3.3.4 (carboxyethyl)arginine β-lactam-synthase

6.3.3.5 O-ureido-D-serine cyclo-ligase

6.3.3.6 carbapenam-3-carboxylate synthase

6.3.3.7 Ni-sirohydrochlorin a,c-diamide reductive cyclase

6.3.4 Other carbon-nitrogen ligases

6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor

6.4 Forming carbon-carbon bonds

6.5 Forming phosphoric-ester bonds

6.6 Forming nitrogen—metal bonds

6.7 Forming nitrogen-nitrogen bonds

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)