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1 Oxidoreductases
2 Transferases
2.1 Transferring one-carbon groups
2.2 Transferring aldehyde or ketonic groups
2.3 Acyltransferases
2.4 Glycosyltransferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.6 Transferring nitrogenous groups
2.7 Transferring phosphorus-containing groups
2.8 Transferring sulfur-containing groups
2.8.1 Sulfurtransferases
2.8.2 Sulfotransferases
2.8.3 CoA-transferases
2.8.4 Transferring alkylthio groups
2.8.5 Thiosulfotransferases
2.9 Transferring selenium-containing groups
2.10 Transferring molybdenum- or tungsten-containing groups
2.10.1 Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors
3 Hydrolases
4 Lyases
5 Isomerases
5.1 Racemases and epimerases
5.2
cis-trans-
Isomerases
5.3 Intramolecular oxidoreductases
5.4 Intramolecular transferases
5.5 Intramolecular lyases
5.5.1 Intramolecular lyases (only sub-subclass identified to date)
5.5.1.1 muconate cycloisomerase
5.5.1.2 3-carboxy-
cis
,
cis
-muconate cycloisomerase
5.5.1.3 tetrahydroxypteridine cycloisomerase
5.5.1.4 inositol-3-phosphate synthase
5.5.1.5 carboxy-
cis
,
cis
-muconate cyclase
5.5.1.6 chalcone isomerase
5.5.1.7 chloromuconate cycloisomerase
5.5.1.8 (+)-bornyl diphosphate synthase
5.5.1.9 cycloeucalenol cycloisomerase
5.5.1.10 α-pinene-oxide decyclase
5.5.1.11 dichloromuconate cycloisomerase
5.5.1.12 copalyl diphosphate synthase
5.5.1.13
ent
-copalyl diphosphate synthase
5.5.1.14
syn
-copalyl-diphosphate synthase
5.5.1.15 terpentedienyl-diphosphate synthase
5.5.1.16 halimadienyl-diphosphate synthase
5.5.1.17 (
S
)-β-macrocarpene synthase
5.5.1.18 lycopene ε-cyclase
5.5.1.19 lycopene β-cyclase
5.5.1.20 prosolanapyrone-III cycloisomerase
5.5.1.21 copal-8-ol diphosphate synthase
5.5.1.22 (–)-bornyl diphosphate synthase
5.5.1.23 aklanonic acid methyl ester cyclase
5.5.1.24 tocopherol cyclase
5.5.1.25 3,6-anhydro-
L
-galactonate cycloisomerase
5.5.1.26 nogalonic acid methyl ester cyclase
5.5.1.27
D
-galactarolactone cycloisomerase
5.5.1.28 (–)-kolavenyl diphosphate synthase
5.5.1.29 (+)-kolavenyl diphosphate synthase
5.5.1.30 labda-7,13-dienyl diphosphate synthase
5.5.1.31 hapalindole H synthase
5.5.1.32 12-
epi
-hapalindole U synthase
5.5.1.33 12-
epi
-fischerindole U synthase
5.5.1.34 (+)-
cis
,
trans
-nepetalactol synthase
5.5.1.35 (+)-
cis
,
cis
-nepetalactol synthase
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.2 Enzymes altering nucleic acid conformation
5.99 Other isomerases
6 Ligases
7 Translocases