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EC Tree
1 Oxidoreductases
2 Transferases
2.1 Transferring one-carbon groups
2.2 Transferring aldehyde or ketonic groups
2.3 Acyltransferases
2.4 Glycosyltransferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.6 Transferring nitrogenous groups
2.6.1 Transaminases
2.6.2 Amidinotransferases (deleted sub-subclass)
2.6.3 Oximinotransferases
2.6.99 Transferring other nitrogenous groups
2.7 Transferring phosphorus-containing groups
2.8 Transferring sulfur-containing groups
2.9 Transferring selenium-containing groups
2.9.1 Selenotransferases
2.10 Transferring molybdenum- or tungsten-containing groups
3 Hydrolases
4 Lyases
5 Isomerases
6 Ligases
6.1 Forming carbon-oxygen bonds
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.1 acetate—CoA ligase
6.2.1.2 medium-chain acyl-CoA ligase
6.2.1.3 long-chain-fatty-acid—CoA ligase
6.2.1.4 succinate—CoA ligase (GDP-forming)
6.2.1.5 succinate—CoA ligase (ADP-forming)
6.2.1.6 glutarate—CoA ligase
6.2.1.7 cholate—CoA ligase
6.2.1.8 oxalate—CoA ligase
6.2.1.9 malate—CoA ligase
6.2.1.10 carboxylic acid—CoA ligase (GDP-forming)
6.2.1.11 biotin—CoA ligase
6.2.1.12 4-coumarate—CoA ligase
6.2.1.13 acetate—CoA ligase (ADP-forming)
6.2.1.14 6-carboxyhexanoate—CoA ligase
6.2.1.15 arachidonate—CoA ligase
6.2.1.16 acetoacetate—CoA ligase
6.2.1.17 propionate—CoA ligase
6.2.1.18 citrate—CoA ligase
6.2.1.19 long-chain-fatty-acid—protein ligase
6.2.1.20 long-chain-fatty-acid—[acyl-carrier-protein] ligase
6.2.1.21 created 1986, deleted 2001
6.2.1.22 [citrate (
pro
-3
S
)-lyase] ligase
6.2.1.23 dicarboxylate—CoA ligase
6.2.1.24 phytanate—CoA ligase
6.2.1.25 benzoate—CoA ligase
6.2.1.26
o
-succinylbenzoate—CoA ligase
6.2.1.27 4-hydroxybenzoate—CoA ligase
6.2.1.28 3α,7α-dihydroxy-5β-cholestanate—CoA ligase
6.2.1.29 (25
R
)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate—CoA ligase
6.2.1.30 phenylacetate—CoA ligase
6.2.1.31 2-furoate—CoA ligase
6.2.1.32 anthranilate—CoA ligase
6.2.1.33 4-chlorobenzoate—CoA ligase
6.2.1.34
trans
-feruloyl-CoA synthase
6.2.1.35 acetate—[acyl-carrier protein] ligase
6.2.1.36 3-hydroxypropionyl-CoA synthase
6.2.1.37 3-hydroxybenzoate—CoA ligase
6.2.1.38 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase
6.2.1.39 [butirosin acyl-carrier protein]—
L
-glutamate ligase
6.2.1.40 4-hydroxybutyrate—CoA ligase (AMP-forming)
6.2.1.41 3-[(3a
S
,4
S
,7a
S
)-7a-methyl-1,5-dioxo-octahydro-1
H
-inden-4-yl]propanoate—CoA ligase
6.2.1.42 3-oxocholest-4-en-26-oate—CoA ligase
6.2.1.43 2-hydroxy-7-methoxy-5-methyl-1-naphthoate—CoA ligase
6.2.1.44 3-(methylthio)propionyl—CoA ligase
6.2.1.45 E1 ubiquitin-activating enzyme
6.2.1.46
L
-
allo
-isoleucine—holo-[CmaA peptidyl-carrier protein] ligase
6.2.1.47 medium-chain-fatty-acid—[acyl-carrier-protein] ligase
6.2.1.48 carnitine—CoA ligase
6.2.1.49 long-chain fatty acid adenylyltransferase FadD28
6.2.1.50 4-hydroxybenzoate adenylyltransferase FadD22
6.2.1.51 4-hydroxyphenylalkanoate adenylyltransferase FadD29
6.2.1.52
L
-firefly luciferin—CoA ligase
6.2.1.53
L
-proline—[
L
-prolyl-carrier protein] ligase
6.2.1.54
D
-alanine—[
D
-alanyl-carrier protein] ligase
6.2.1.55 E1 SAMP-activating enzyme
6.2.1.56 4-hydroxybutyrate—CoA ligase (ADP-forming)
6.2.1.57 long-chain fatty acid adenylase/transferase FadD23
6.2.1.58 isophthalate—CoA ligase
6.2.1.59 long-chain fatty acid adenylase/transferase FadD26
6.2.1.60 marinolic acid—CoA ligase
6.2.1.61 salicylate—[aryl-carrier protein] ligase
6.2.1.62 3,4-dihydroxybenzoate—[aryl-carrier protein] ligase
6.2.1.63
L
-arginine—[
L
-arginyl-carrier protein] ligase
6.2.1.64 E1 NEDD8-activating enzyme
6.2.1.65 salicylate—CoA ligase
6.2.1.66 glyine—[glycyl-carrier protein] ligase
6.2.1.67
L
-alanine—[
L
-alanyl-carrier protein] ligase
6.2.1.68
L
-glutamate—[
L
-glutamyl-carrier protein] ligase
6.2.1.69
L
-cysteine—[
L
-cysteinyl-carrier protein] ligase
6.2.1.70
L
-threonine—[
L
-threonyl-carrier protein] ligase
6.2.1.71 2,3-dihydroxybenzoate—[aryl-carrier protein] ligase
6.2.1.72
L
-serine—[
L
-seryl-carrier protein] ligase
6.2.1.73
L
-tryptophan—[
L
-tryptophyl-carrier protein] ligase
6.2.1.74 3-amino-5-hydroxybenzoate—[acyl-carrier protein] ligase
6.2.1.75 indoleacetate—CoA ligase
6.2.1.76 malonate—CoA ligase
6.2.2 Amide---thiol ligases
6.3 Forming carbon-nitrogen bonds
6.4 Forming carbon-carbon bonds
6.5 Forming phosphoric-ester bonds
6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
6.6 Forming nitrogenmetal bonds
6.7 Forming nitrogen-nitrogen bonds
7 Translocases