EC Explorer

EC 1.1.1.44 Details
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EC number
1.1.1.44
Accepted name
phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
Reaction
6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+
Other name(s)
phosphogluconic acid dehydrogenase, 6-phosphogluconic dehydrogenase, 6-phosphogluconic carboxylase, 6-phosphogluconate dehydrogenase (decarboxylating), 6-phospho-D-gluconate dehydrogenase
Systematic name
6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)
CAS registry number
9073-95-4
Comment
The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions. Highly specific for NADP+. cf. EC 1.1.1.343, phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating).
History
created 1961, modified 2013
EC Browser
1 Oxidoreductases (9634 organisms) download 2925940 sequences with EC number 1 in fasta format download 2925940 sequences with EC number 1 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 1) as tabstop separated file
1.1.1.68 created 1965, deleted 1978 [transferred to EC 1.1.99.15, deleted 1980] show the reaction
1.1.1.70 created 1965, deleted 1978 show the reaction
1.1.1.74 created 1972, deleted 1976 show the reaction
1.1.1.89 created 1972, deleted 1976 show the reaction
1.1.1.109 created 1972, deleted 1976 show the reaction
1.1.1.139 created 1972, deleted 1978 show the reaction
1.1.1.155 created 1976, deleted 2004 show the reaction
1.1.1.171 created 1978, deleted 1984 show the reaction
1.1.1.180 created 1983, deleted 1984 show the reaction
1.1.1.182 created 1983, deleted 1990 show the reaction
1.1.1.204 created 1972 as EC 1.2.1.37, transferred 1984 to EC 1.1.1.204, modified 1989, deleted 2004 show the reaction
1.1.1.242 created 1992, deleted 2001 show the reaction
1.1.1.249 provisional version created 1999, deleted 1999 (reinstated 2001 as EC 2.5.1.46) show the reaction
1.1.1.253 created 1999, deleted 2003 show the reaction
2 Transferases (6601 organisms) download 4558689 sequences with EC number 2 in fasta format download 4558689 sequences with EC number 2 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 2) as tabstop separated file
3 Hydrolases (9513 organisms) download 2408489 sequences with EC number 3 in fasta format download 2408489 sequences with EC number 3 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 3) as tabstop separated file
4 Lyases (5106 organisms) download 1406112 sequences with EC number 4 in fasta format download 1406112 sequences with EC number 4 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 4) as tabstop separated file
5 Isomerases (2066 organisms) download 874027 sequences with EC number 5 in fasta format download 874027 sequences with EC number 5 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 5) as tabstop separated file
6 Ligases (1540 organisms) download 1326407 sequences with EC number 6 in fasta format download 1326407 sequences with EC number 6 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 6) as tabstop separated file
7 Translocases (833 organisms) download 459397 sequences with EC number 7 in fasta format download 459397 sequences with EC number 7 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 7) as tabstop separated file