EC Explorer

EC 2.1.2.10 Details
show Brenda entry
EC number
2.1.2.10
Accepted name
aminomethyltransferase
Reaction
[protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3
Other name(s)
S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming), T-protein, glycine synthase, tetrahydrofolate aminomethyltransferase, [protein]-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming)
Systematic name
[protein]-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming)
CAS registry number
37257-08-2
Comment
A component, with EC 1.4.4.2 glycine dehydrogenase (decarboxylating) and EC 1.8.1.4, dihydrolipoyl dehydrogenanse, of the glycine cleavage system, formerly known as glycine synthase. The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein [3].
History
created 1972, modified 2003, modified 2006
EC Browser
1 Oxidoreductases (9634 organisms) download 2925940 sequences with EC number 1 in fasta format download 2925940 sequences with EC number 1 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 1) as tabstop separated file
2 Transferases (6601 organisms) download 4558689 sequences with EC number 2 in fasta format download 4558689 sequences with EC number 2 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 2) as tabstop separated file
2.1.1 Methyltransferases (1127 organisms) download 551858 sequences with EC number 2.1.1 in fasta format download 551858 sequences with EC number 2.1.1 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 2.1.1) as tabstop separated file
2.1.2.6 created 1965, deleted 1984 show the reaction
2.1.2.12 created 1983, deleted 1984 show the reaction
2.3 Acyltransferases (1670 organisms) download 563934 sequences with EC number 2.3 in fasta format download 563934 sequences with EC number 2.3 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 2.3) as tabstop separated file
2.4 Glycosyltransferases (1877 organisms) download 467031 sequences with EC number 2.4 in fasta format download 467031 sequences with EC number 2.4 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 2.4) as tabstop separated file
3 Hydrolases (9513 organisms) download 2408489 sequences with EC number 3 in fasta format download 2408489 sequences with EC number 3 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 3) as tabstop separated file
4 Lyases (5106 organisms) download 1406112 sequences with EC number 4 in fasta format download 1406112 sequences with EC number 4 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 4) as tabstop separated file
5 Isomerases (2066 organisms) download 874027 sequences with EC number 5 in fasta format download 874027 sequences with EC number 5 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 5) as tabstop separated file
6 Ligases (1540 organisms) download 1326407 sequences with EC number 6 in fasta format download 1326407 sequences with EC number 6 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 6) as tabstop separated file
7 Translocases (833 organisms) download 459397 sequences with EC number 7 in fasta format download 459397 sequences with EC number 7 as tabstop The data in BRENDA allow the calculation or simulation of metabolic pathways by extracting the information of substrate/product chains and the corresponding kinetic data of the preceding and following enzymes in the Boehringer and KEGG metabolism (with the risk of including ?pathways? with non-natural compounds). version Download 2822 PDB numbers (EC 7) as tabstop separated file