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EC 4.1.1.112 Details
EC number
4.1.1.112
Accepted name
oxaloacetate decarboxylase
Reaction
oxaloacetate = pyruvate + CO2
Other name(s)
oxaloacetate β-decarboxylase, oxalacetic acid decarboxylase, oxalate β-decarboxylase, oxaloacetate carboxy-lyase
Systematic name
oxaloacetate carboxy-lyase (pyruvate-forming)
CAS registry number
9024-98-0
Comment
Requires a divalent metal cation. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn2+, while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg2+. Unlike EC 7.2.4.2 [oxaloacetate decarboxylase (Na+ extruding)], there is no evidence of the enzyme’s involvement in Na+ transport.
History
created 1961 as EC 4.1.1.3, modified 1986, modified 2000, part transferred 2018 to EC 4.1.1.112
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EC Tree
1 Oxidoreductases
2 Transferases
3 Hydrolases
4 Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.1 pyruvate decarboxylase
4.1.1.2 oxalate decarboxylase
4.1.1.3 oxaloacetate decarboxylase
4.1.1.4 acetoacetate decarboxylase
4.1.1.5 acetolactate decarboxylase
4.1.1.6 cis-aconitate decarboxylase
4.1.1.7 benzoylformate decarboxylase
4.1.1.8 oxalyl-CoA decarboxylase
4.1.1.9 malonyl-CoA decarboxylase
4.1.1.10 created 1961, deleted 1972
4.1.1.11 aspartate 1-decarboxylase
4.1.1.12 aspartate 4-decarboxylase
4.1.1.13 created 1961, deleted 1972
4.1.1.14 valine decarboxylase
4.1.1.15 glutamate decarboxylase
4.1.1.16 hydroxyglutamate decarboxylase
4.1.1.17 ornithine decarboxylase
4.1.1.18 lysine decarboxylase
4.1.1.19 arginine decarboxylase
4.1.1.20 diaminopimelate decarboxylase
4.1.1.21 phosphoribosylaminoimidazole carboxylase
4.1.1.22 histidine decarboxylase
4.1.1.23 orotidine-5′-phosphate decarboxylase
4.1.1.24 aminobenzoate decarboxylase
4.1.1.25 tyrosine decarboxylase
4.1.1.26 created 1961, deleted 1972
4.1.1.27 created 1961, deleted 1972
4.1.1.28 aromatic-L-amino-acid decarboxylase
4.1.1.29 sulfinoalanine decarboxylase
4.1.1.30 pantothenoylcysteine decarboxylase
4.1.1.31 phosphoenolpyruvate carboxylase
4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
4.1.1.33 diphosphomevalonate decarboxylase
4.1.1.34 dehydro-L-gulonate decarboxylase
4.1.1.35 UDP-glucuronate decarboxylase
4.1.1.36 phosphopantothenoylcysteine decarboxylase
4.1.1.37 uroporphyrinogen decarboxylase
4.1.1.38 phosphoenolpyruvate carboxykinase (diphosphate)
4.1.1.39 ribulose-bisphosphate carboxylase
4.1.1.40 hydroxypyruvate decarboxylase
4.1.1.41 (S)-methylmalonyl-CoA decarboxylase
4.1.1.42 carnitine decarboxylase
4.1.1.43 phenylpyruvate decarboxylase
4.1.1.44 4-carboxymuconolactone decarboxylase
4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase
4.1.1.46 o-pyrocatechuate decarboxylase
4.1.1.47 tartronate-semialdehyde synthase
4.1.1.48 indole-3-glycerol-phosphate synthase
4.1.1.49 phosphoenolpyruvate carboxykinase (ATP)
4.1.1.50 adenosylmethionine decarboxylase
4.1.1.51 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase
4.1.1.52 6-methylsalicylate decarboxylase
4.1.1.53 phenylalanine decarboxylase
4.1.1.54 dihydroxyfumarate decarboxylase
4.1.1.55 4,5-dihydroxyphthalate decarboxylase
4.1.1.56 3-oxolaurate decarboxylase
4.1.1.57 methionine decarboxylase
4.1.1.58 orsellinate decarboxylase
4.1.1.59 gallate decarboxylase
4.1.1.60 stipitatonate decarboxylase
4.1.1.61 4-hydroxybenzoate decarboxylase
4.1.1.62 gentisate decarboxylase
4.1.1.63 protocatechuate decarboxylase
4.1.1.64 2,2-dialkylglycine decarboxylase (pyruvate)
4.1.1.65 phosphatidylserine decarboxylase
4.1.1.66 uracil-5-carboxylate decarboxylase
4.1.1.67 UDP-galacturonate decarboxylase
4.1.1.68 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase
4.1.1.69 3,4-dihydroxyphthalate decarboxylase
4.1.1.70 glutaconyl-CoA decarboxylase
4.1.1.71 2-oxoglutarate decarboxylase
4.1.1.72 branched-chain-2-oxoacid decarboxylase
4.1.1.73 tartrate decarboxylase
4.1.1.74 indolepyruvate decarboxylase
4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase
4.1.1.76 arylmalonate decarboxylase
4.1.1.77 2-oxo-3-hexenedioate decarboxylase
4.1.1.78 acetylenedicarboxylate decarboxylase
4.1.1.79 sulfopyruvate decarboxylase
4.1.1.80 4-hydroxyphenylpyruvate decarboxylase
4.1.1.81 threonine-phosphate decarboxylase
4.1.1.82 phosphonopyruvate decarboxylase
4.1.1.83 4-hydroxyphenylacetate decarboxylase
4.1.1.84 D-dopachrome decarboxylase
4.1.1.85 3-dehydro-L-gulonate-6-phosphate decarboxylase
4.1.1.86 diaminobutyrate decarboxylase
4.1.1.87 malonyl-S-ACP decarboxylase
4.1.1.88 biotin-independent malonate decarboxylase
4.1.1.89 biotin-dependent malonate decarboxylase
4.1.1.90 peptidyl-glutamate 4-carboxylase
4.1.1.91 salicylate decarboxylase
4.1.1.92 indole-3-carboxylate decarboxylase
4.1.1.93 pyrrole-2-carboxylate decarboxylase
4.1.1.94 ethylmalonyl-CoA decarboxylase
4.1.1.95 L-glutamyl-[BtrI acyl-carrier protein] decarboxylase
4.1.1.96 carboxynorspermidine decarboxylase
4.1.1.97 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
4.1.1.98 4-hydroxy-3-polyprenylbenzoate decarboxylase
4.1.1.99 phosphomevalonate decarboxylase
4.1.1.100 prephenate decarboxylase
4.1.1.101 malolactic enzyme
4.1.1.102 phenacrylate decarboxylase
4.1.1.103 γ-resorcylate decarboxylase
4.1.1.104 3-dehydro-4-phosphotetronate decarboxylase
4.1.1.105 L-tryptophan decarboxylase
4.1.1.106 fatty acid photodecarboxylase
4.1.1.107 3,4-dihydroxyphenylacetaldehyde synthase
4.1.1.108 4-hydroxyphenylacetaldehyde synthase
4.1.1.109 phenylacetaldehyde synthase
4.1.1.110 bisphosphomevalonate decarboxylase
4.1.1.111 siroheme decarboxylase
4.1.1.112 oxaloacetate decarboxylase
4.1.1.113 trans-aconitate decarboxylase
4.1.1.114 cis-3-alkyl-4-alkyloxetan-2-one decarboxylase
4.1.1.115 indoleacetate decarboxylase
4.1.1.116 D-ornithine/D-lysine decarboxylase
4.1.1.117 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase
4.1.1.118 isophthalyl-CoA decarboxylase
4.1.1.119 phenylacetate decarboxylase
4.1.1.120 3-oxoisoapionate decarboxylase
4.1.1.121 3-oxoisoapionate-4-phosphate decarboxylase
4.1.1.122 L-cysteate decarboxylase
4.1.1.123 phenyl-phosphate phosphatase/carboxylase
4.1.2 Aldehyde-lyases
4.1.3 Oxo-acid-lyases
4.1.99 Other carbon-carbon lyases
4.2 Carbon-oxygen lyases
4.3 Carbon-nitrogen lyases
4.4 Carbon-sulfur lyases
4.5 Carbon-halide lyases
4.6 Phosphorus-oxygen lyases
4.7 carbon-phosphorus lyases
4.8 Nitrogen-oxygen lyases
4.98 ATP-independent chelatases
4.99 Other lyases
5 Isomerases
6 Ligases
7 Translocases