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EC 4.1.2.13 Details
EC number
4.1.2.13
Accepted name
fructose-bisphosphate aldolase
Reaction
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate
Other name(s)
aldolase, fructose-1,6-bisphosphate triosephosphate-lyase, fructose diphosphate aldolase, diphosphofructose aldolase, fructose 1,6-diphosphate aldolase, ketose 1-phosphate aldolase, phosphofructoaldolase, zymohexase, fructoaldolase, fructose 1-phosphate aldolase, fructose 1-monophosphate aldolase, 1,6-diphosphofructose aldolase, SMALDO, D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase
Systematic name
D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)
CAS registry number
9024-52-6
Comment
Also acts on (3S,4R)-ketose 1-phosphates. The yeast and bacterial enzymes are zinc proteins. The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.
History
created 1965, modified 1999 (EC 4.1.2.7 created 1961, incorporated 1972)
EC Tree
4.1.2.1 created 1961, deleted 1972
4.1.2.3 created 1961, deleted 1972
4.1.2.6 created 1961, deleted 1972
4.1.2.7 created 1961, deleted 1972
4.1.2.15 created 1965, modified 1976, deleted 2002
4.1.2.16 created 1965, deleted 2002
4.1.2.31 created 1978, deleted 1982