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EC 5.5.1.7 Details
EC number
5.5.1.7
Accepted name
chloromuconate cycloisomerase
Reaction
(2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate
Other name(s)
muconate cycloisomerase II, 2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing), 2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (ring-opening)
Systematic name
(2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (ring-opening)
CAS registry number
95990-33-3
Comment
Requires Mn2+. The product of cycloisomerization of 3-chloro-cis,cis-muconate spontaneously eliminates chloride to produce cis-4-carboxymethylenebut-2-en-4-olide. Also acts on 2-chloro-cis,cis-muconate. Not identical with EC 5.5.1.1 (muconate cycloisomerase) or EC 5.5.1.11 (dichloromuconate cycloisomerase).
History
created 1983
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