Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(S)-1-indanol + NADP+
?
-
-
-
-
?
(S)-1-tetralol + NADP+
?
-
-
-
-
?
(S)-methyl 3-hydroxybutyrate + NADP+
methyl acetoacetate + NADPH + H+
(S)-tetralol + NAD(P)+
3,4-dihydronaphthalen-1(2H)-one + NAD(P)H + H+
-
-
-
?
1,2-cyclohexanedione + NADP+
?
1,2-cyclohexanedione + NADPH + H+
?
-
-
-
-
r
1-acenaphthenol + NAD+
? + NADH + H+
-
-
-
?
1-phenyl-1,2-propanedione + NADPH
NADP+ + ?
11-deoxycorticosterone + NAD(P)H
4-pregnen-20alpha,21-diol-3-one + NAD(P)+
11-deoxycortisol + NADH
? + NAD+
11-deoxycortisol + NADH + H+
? + NAD+
17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD(P)+
17alpha-hydroxyprogesterone + NAD(P)H
17alpha,21-dihydroxy-5beta-pregnan-3,20-dione + NADPH + H+
17alpha,20alpha,21-trihydroxy-5beta-pregnane-3-one + NADP+
-
-
-
-
r
17alpha,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADPH + H+
17alpha,20alpha,21-trihydroxy-5beta-pregnane-3,11-dione + NADP+
-
-
-
-
r
17alpha,21-dihydroxyadrenocorticosteroid + NAD(P)H
? + NADP+
-
NADH preferred
-
?
17alpha-hydroxy-progesterone + NADH + H+
17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD+
-
-
-
-
r
17alpha-hydroxycorticosterone + NADPH
? + NADP+
-
less reactive than with 17alpha-hydroxyrogesterone
-
?
17alpha-hydroxypregnenolone + NADPH
? + NADP+
17alpha-hydroxyprogesterone + NAD(P)H
17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD(P)+
17alpha-hydroxyprogesterone + NAD(P)H + H+
17alpha,20alpha-dihydroxy-pregn-4-en-3-one + NAD(P)+
17alpha-hydroxyprogesterone + NADPH
17alpha,20alpha-dihydroxyprogesterone + NADP+
17alpha-hydroxyprogesterone + NADPH + H+
17alpha,20alpha-dihydroxy-pregn-4-en-3-one + NADP+
17beta-estradiol + NADP+
?
-
-
-
-
?
2,3-butanedione + NADPH
? + NADP+
2,3-heptanedione + NADPH
NADP+ + ?
2,3-hexanedione + NADPH
NADP+ + ?
2,3-pentanedione + NADPH
NADP+ + ?
2,4-pentanedione + NADP+
?
2,4-pentanedione + NADPH + H+
4-hydroxypentan-2-one + NADP+
-
-
-
-
r
2-amino-8-((2-fluoro-4-methoxybenzyl)thio)-1,9-dihydro-6H-purin-6-one + NADP+
?
-
-
-
-
r
2-tert-butyl-1,4-benzoquinone + NADPH + H+
?
-
-
-
-
?
20alpha-dihydroprogesterone + NAD+
progesterone + NADH
-
-
-
?
20alpha-dihydroprogesterone + NADP+
progesterone + NADPH
-
-
-
?
20alpha-hydroxy-5alpha-pregnan-3-one + NADPH + H+
5alpha-pregnan-20alpha,3alpha-diol + NADP+
-
-
-
-
r
20alpha-hydroxy-5beta-pregnan-3-one + NADP+
5beta-pregnane-3,20-dione + NADPH
-
-
-
?
20alpha-hydroxypregn-4-en-3-one + 3-acetylpyridine adenine dinucleotide phosphate
?
-
-
-
-
r
20alpha-hydroxypregn-4-en-3-one + nicotinamide 1,N6-ethenoadenine dinucleotide phosphate
?
-
-
-
-
r
20alpha-hydroxypregn-4-en-3-one + nicotinamide hypoxanthine dinucleotide phosphate
?
-
-
-
-
r
20alpha-hydroxypregn-4-en-3-one + thionicotinamide adenine dinucleotide phosphate
?
-
-
-
-
r
20alpha-hydroxyprogesterone + NAD+
progesterone + NADH
-
-
-
-
?
20alpha-hydroxyprogesterone + NADP+
?
-
-
-
-
?
20alpha-hydroxyprogesterone + NADP+
progesterone + NADPH
3,4-hexanedione + NADP+
?
3-deoxyglucosone + NADPH + H+
?
-
-
-
-
?
3alpha-hydroxy-5-alpha-pregnan-20-one + NADPH + H+
5alpha-pregnan-3alpha,20alpha-diol + NADP+
-
-
-
-
r
3alpha-hydroxy-5alpha-pregnan-20-one + NADPH + H+
5alpha-pregnan-3alpha,20alpha-diol + NADP+
-
-
-
-
r
4-androstene-3,17-dione + NADPH + H+
?
-
-
-
-
?
4-chromanol + NADP+
?
-
-
-
-
?
4-hydroxy-2-nonenal + NADPH + H+
?
-
-
-
-
?
4-nitroacetophenone + NADPH + H+
?
-
-
-
-
?
4-nitrobenzaldehyde + NADPH
4-nitrobenzyl alcohol + NADP+
4-oxo-2-hexenal + NADPH + H+
?
-
-
-
-
?
4-oxo-2-nonenal + NADPH + H+
?
-
-
-
-
?
4-pregnen-20alpha-ol-3-one + NAD(P)+
4-pregnen-3,20-dione + NAD(P)H + H+
-
-
-
-
r
4-pregnen-3alpha-ol-20-one + NADPH + H+
?
-
-
-
-
?
5-androstene-3beta,17beta-diol + NADP+
?
-
-
-
-
?
5alpha-androstan-3alpha,17beta-diol + NADP+
?
-
-
-
-
?
5alpha-androstan-3alpha-ol-17-one + NADPH + H+
?
-
-
-
-
?
5alpha-androstan-3beta,17beta-diol + NADP+
?
-
-
-
-
?
5alpha-androstan-3beta-ol-17-one + NADPH + H+
?
-
-
-
-
?
5alpha-dihydroprogesterone + NADPH + H+
5alpha,20alpha-tetrahydroprogesterone + NADP+
5alpha-dihydrotestosterone + NADP+
?
-
-
-
-
?
5alpha-dihydrotestosterone + NADPH + H+
?
-
-
-
-
?
5alpha-dihydrotestosterone + NADPH + H+
? + NADP+
-
-
-
-
?
5alpha-pregnan-20alpha-ol-3-one + NAD(P)+
5alpha-pregnan-3,20-dione + NAD(P)H
-
-
-
-
r
5alpha-pregnan-20alpha-ol-3-one + NAD(P)+
5alpha-pregnane-3,20-dione + NAD(P)H
-
-
-
-
r
5alpha-pregnan-20alpha-ol-3-one + NADP+
5beta-pregnan-3,20-dione + NADPH + H+
-
-
-
-
r
5alpha-pregnan-20alpha-ol-3-one + NADP+
?
-
-
-
-
?
5alpha-pregnan-3,20-dione + NADPH + H+
?
-
-
-
-
?
5alpha-pregnan-3alpha,20alpha-diol + NADP+
?
-
-
-
-
?
5alpha-pregnan-3alpha,21-diol-20-one + NADPH + H+
?
-
-
-
-
?
5alpha-pregnan-3alpha-ol-20-one + NAD(P)H
5alpha-pregnan-3alpha,20alpha-diol + NAD(P)+
-
-
-
-
r
5alpha-pregnan-3alpha-ol-20-one + NAD(P)H + H+
5alpha-pregnan-3alpha,20alpha-diol + NAD(P)+
-
-
-
-
r
5alpha-pregnan-3alpha-ol-20-one + NADPH + H+
?
-
-
-
-
?
5alpha-pregnane-21-ol-3,20-dione + NAD(P)H
5alpha-pregnane-20alpha,21-diol-3-one + NAD(P)+
-
-
-
-
r
5alpha-pregnane-3,20-dione + NAD(P)H
5alpha-pregnan-20alpha-ol-3-one + NAD(P)+
-
-
-
-
r
5alpha-pregnane-3alpha,20alpha-diol + NAD(P)+
3alpha-hydroxy-5alpha-pregnan-20-one + NAD(P)H + H+
5alpha-pregnane-3alpha,21-diol-20-one + NAD(P)H + H+
5alpha-pregnane-3alpha,20alpha,21-triol + NAD(P)+
-
-
-
-
r
5beta-androstan-17beta-ol-3-one + NADP+
?
-
-
-
-
?
5beta-androstan-3alpha,17beta-diol + NADP+
?
-
-
-
-
?
5beta-androstan-3alpha-ol-17-one + NADPH + H+
?
-
-
-
-
?
5beta-androstan-3beta,17beta-diol + NADP+
?
-
-
-
-
?
5beta-androstan-3beta-ol-17-one + NADPH + H+
?
-
-
-
-
?
5beta-dihydrocortisol + NADH
? + NAD+
-
-
-
r
5beta-pregnan-20alpha-ol-3-one + NAD(P)+
5beta-pregnan-3,20-dione + NAD(P)H
-
-
-
-
r
5beta-pregnan-20alpha-ol-3-one + NADP+
?
5beta-pregnan-3,20-dione + NADPH + H+
5alpha-pregnan-20alpha-ol-3-one + NADP+
-
-
-
-
r
5beta-pregnan-3alpha,20alpha-diol + NADP+
?
-
-
-
-
?
5beta-pregnan-3alpha,21-diol-20-one + NADPH + H+
?
-
-
-
-
?
5beta-pregnan-3alpha-ol-20-one + NAD(P)H
5beta-pregnan-3alpha,20alpha-diol + NAD(P)+
-
-
-
-
r
5beta-pregnan-3alpha-ol-20-one + NAD(P)H
5beta-pregnane-3alpha,20alpha-diol + NAD(P)+
-
-
-
-
r
5beta-pregnan-3alpha-ol-20-one + NAD(P)H + H+
5alpha-pregnan-3alpha,20alpha-diol + NAD(P)+
-
-
-
?
5beta-pregnan-3alpha-ol-20-one + NADPH + H+
?
-
-
-
-
?
5beta-pregnane-3,20-dione + NAD(P)H + H+
5alpha-pregnan-20alpha-ol-3-one + NAD(P)+
-
-
-
-
r
5beta-pregnane-3alpha,20alpha-diol + NAD(P)+
5beta-pregnan-20alpha-ol-3-one + NAD(P)H + H+
6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione + NADPH + H+
?
-
-
-
-
?
7alpha-hydroxy-dehydroepiandrosterone + NADPH + H+
?
-
-
-
-
?
9,10-phenanthrenequinone + NADPH
NADP+ + ?
-
-
-
-
?
acetoacetyl-CoA + NADPH
NADP+ + ?
acrolein + NADPH + H+
?
-
-
-
-
?
all-trans-retinal + NADPH + H+
?
-
-
-
-
?
alpha-tetralone + NADPH + H+
?
-
-
-
-
?
befunolol + NADPH + H+
?
-
-
-
-
?
benzaldehyde + NADPH
benzyl alcohol + NADP+
-
-
-
-
?
benzene dihydrodiol + NADP+
2-hydroxycyclohexa-3,5-diene-1-one + NADPH + H+
-
-
-
-
r
benzyl acetoacetate + NADPH + H+
?
beta-ionol + NADP+
?
-
-
-
-
?
camphorquinone + NADP+
?
-
-
-
-
r
cis-benzene-1,2-dihydrodiol + NADP+
?
corticosterone + NADH + H+
? + NAD+
corticosterone + NADPH + H+
? + NADP+
-
less reactive than with 17alpha-hydroxyprogesterone
-
?
cortisol + NADH
20alpha-dihydrocortisol + NAD+
cortisol + NADH + H+
20beta-hydroxycortisol + NAD+
cortisone + NADH
? + NAD+
D-galactose + NADPH
NADP+ + ?
-
-
-
-
?
D-glucose + NADPH
NADP+ + ?
-
-
-
-
?
D-glyceraldehyde + NADPH + H+
glycerol + NADP+
D-lactaldehyde + NADPH + H+
?
daunorubicin + NADPH + H+
daunorubicinol + NADP+
dehydroepiandrosterone + NADPH + H+
?
-
-
-
-
?
dehydroepiandrosterone 3-sulfate + NADPH + H+
?
-
-
-
-
?
diacetyl + NADPH + H+
?
-
-
-
-
?
dihydrotestosterone + NADPH
? + NADP+
-
-
-
-
r
dihydrotestosterone + NADPH + H+
4-androsten-3alpha,17beta-diol + NADP+
DL-glyceraldehyde + NADPH
glycerol + NADP+
-
-
-
-
?
DL-glyceraldehyde 3-phosphate + NADPH + H+
glycerol 3-phosphate + NADP+
dydrogesterone + NADH + H+
20alpha-hydroxydydrogesterone + NAD+
-
-
-
-
?
estrone + NADPH + H+
?
-
-
-
-
?
estrone 3-sulfate + NADPH + H+
?
-
-
-
-
?
ethyl 2-methylacetoacetate + NADPH
NADP+ + ?
ethyl 3-oxovalerate + NADPH + H+
?
ethyl 4-chloroacetoacetate + NADPH
NADP+ + ?
ethyl acetoaetate + NADPH
(S)-ethyl 3-hydroxybutyrate + NADP+
ethyl benzoylacetate + NADPH + H+
?
ethyl pyruvate + NADPH
NADP+ + ?
geraniol + NADP+
?
-
-
-
-
?
hexanal + NADPH + H+
?
-
-
-
-
?
isatin + NADP+
?
-
-
-
-
?
isocaproaldehyde + NADPH + H+
?
-
-
-
-
?
ketotifen + NADPH + H+
?
-
-
-
-
?
menadione + NADPH + H+
?
-
-
-
-
?
methyl acetoacetate + NADPH + H+
?
methylglyoxal + NADPH
NADP+ + ?
methylglyoxal + NADPH + H+
?
-
-
-
-
?
n-butyl acetoacetate + NADPH + H+
?
n-hexyl acetoacetate + NADPH + H+
?
n-octyl acetoacetate + NADPH + H+
?
nonanal + NADPH + H+
?
-
-
-
-
?
phenylglyoxal + NADPH + H+
?
-
-
-
-
r
progesterone + NAD(P)+
20alpha-hydroxyprogesterone + NAD(P)H + H+
-
-
-
?
progesterone + NAD(P)H
20alpha-hydroxypregn-4-en-3-one + NAD(P)+
progesterone + NAD(P)H
20alpha-hydroxyprogesterone + NAD(P)+
progesterone + NAD(P)H + H+
20alpha-hydroxyprogesterone + NAD(P)+
progesterone + NADH
20alpha-hydroxyprogesterone + NAD+
-
-
-
-
?
progesterone + NADH + H+
20alpha-hydroxyprogesterone + NAD+
progesterone + NADPH
20alpha-hydroxyprogesterone + NADP+
progesterone + NADPH + H+
20alpha-hydroxyprogesterone + NADP+
-
-
-
-
?
prostaglandin E2 + NADPH
NADP+ + ?
-
low activity
-
-
?
pyridine 3-aldehyde + NADPH + H+
?
-
-
-
-
?
pyridine-3-aldehyde + NADPH
NADP+ + ?
pyridine-4-aldehyde + NADP+
?
testosterone + NADP+
?
-
-
-
-
?
tetrahydrocortisol + NADH + H+
? + NAD+
trans-1S,2S-cyclohexanediol + NADP+
?
trans-2-hexenal + NADPH + H+
?
-
-
-
-
?
trans-2-nonenal + NADPH + H+
?
-
-
-
-
?
trans-benzene dihydrodiol + NADP+
?
-
-
-
-
?
trans-benzene-1S,2S-dihydrodiol + NADP+
?
additional information
?
-
(S)-methyl 3-hydroxybutyrate + NADP+
methyl acetoacetate + NADPH + H+
-
-
-
-
r
(S)-methyl 3-hydroxybutyrate + NADP+
methyl acetoacetate + NADPH + H+
-
-
-
-
r
1,2-cyclohexanedione + NADP+
?
-
66% activity compared to pyridine 3-aldehyde
-
-
r
1,2-cyclohexanedione + NADP+
?
-
50% activity compared to pyridine 3-aldehyde
-
-
r
1-phenyl-1,2-propanedione + NADPH
NADP+ + ?
-
-
-
-
?
1-phenyl-1,2-propanedione + NADPH
NADP+ + ?
-
-
-
-
?
11-deoxycorticosterone + NAD(P)H
4-pregnen-20alpha,21-diol-3-one + NAD(P)+
-
-
-
-
?
11-deoxycorticosterone + NAD(P)H
4-pregnen-20alpha,21-diol-3-one + NAD(P)+
-
-
-
-
?
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
more
top
