Any feedback?
Please rate this page

BRENDA support

show all | hide all No of entries

Information on EC - tropinone reductase I

for references in articles please use BRENDA:EC1.1.1.206
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
       tropinone reductase I
IUBMB Comments
Also oxidizes other tropan-3alpha-ols, but not the corresponding beta-derivatives . This enzyme along with EC, tropinone reductase II, represents a branch point in tropane alkaloid metabolism . Tropine (the product of EC is incorporated into hyoscyamine and scopolamine whereas pseudotropine (the product of EC is the first specific metabolite on the pathway to the calystegines . Both enzymes are always found together in any given tropane-alkaloid-producing species, have a common substrate, tropinone, and are strictly stereospecific .
Specify your search results
Select one or more organisms in this record: ?
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
tropinone reductase, tropinone reductase i, batri, dntr1, tropine-forming reductase, tropine dehydrogenase, wstr-i, dstri, tropinone reductase-i, tropine-forming tropinone reductase, more
tropine + NADP+ = tropinone + NADPH + H+
show the reaction diagram