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Information on EC 1.1.1.23 - histidinol dehydrogenase

for references in articles please use BRENDA:EC1.1.1.23

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IUBMB Comments

Also oxidizes L-histidinal. The Neurospora enzyme also catalyses the reactions of EC 3.5.4.19 (phosphoribosyl-AMP cyclohydrolase) and EC 3.6.1.31 (phosphoribosyl-ATP diphosphatase).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes

Synonyms
hdh, histidinol dehydrogenase, his4 protein, l-histidinol dehydrogenase, bshdh, l-histidinol:nad+ oxidoreductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
show the reaction diagram