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BRENDA support

Information on EC 1.1.1.274 - 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)

for references in articles please use BRENDA:EC1.1.1.274

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IUBMB Comments

The enzyme is involved in the catabolism of 2,5-didehydrogluconate. cf. EC 1.1.1.346, 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming).

The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

Synonyms
2,5-dkg reductase, 2,5-dkg, 2,5-dkgr, 2,5-diketo-d-gluconate reductase, beta-keto ester reductase, yqhe reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
ketogluconate metabolism, L-ascorbate biosynthesis VIII (engineered pathway)