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Information on EC 1.1.1.338 - (2R)-3-sulfolactate dehydrogenase (NADP+)

for references in articles please use BRENDA:EC1.1.1.338

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IUBMB Comments

The enzyme from the bacterium Chromohalobacter salexigens can only utilize NADP+. It functions both biosynthetically in coenzyme M biosynthesis and degradatively, in the degradation of sulfolactate. It can not use (S)-malate and (S)-lactate.

The enzyme appears in viruses and cellular organisms

Synonyms
(R)-sulfolactate dehydrogenase, (R)-sulfolactate:NAD+ oxidoreductase, (R)-sulfolactate:NADP+ oxidoreductase, ComC, L-sulfolactate dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2R)-3-sulfolactate + NADP+ = 3-sulfopyruvate + NADPH + H+
show the reaction diagram
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