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Information on EC 1.1.1.358 - 2-dehydropantolactone reductase

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IUBMB Comments
The enzyme participates in an alternative pathway for biosynthesis of (R)-pantothenate (vitamin B5). This entry covers enzymes whose stereo specificity for NADP+ is not known. cf. EC 1.1.1.168 2-dehydropantolactone reductase (Re-specific) and EC 1.1.1.214, 2-dehydropantolactone reductase (Si-specific).
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Word Map
The expected taxonomic range for this enzyme is: Saccharomycetales
Synonyms
cpr-01, corcpr, ketopantoyl-lactone reductase, cducpr, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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