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Information on EC 1.1.1.406 - galactitol 2-dehydrogenase (L-tagatose-forming)

for references in articles please use BRENDA:EC1.1.1.406

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IUBMB Comments

The enzyme, characterized in the bacterium Rhodobacter sphaeroides, has a wide subtrate specificity. In addition to galactitol, it primarily oxidizes D-threitol and xylitol, and in addition to L-tagatose, it primarily reduces L-erythrulose, D-ribulose and L-glyceraldehyde. It is specific for NAD+. The enzyme also shows activity with D-tagatose (cf. EC 1.1.1.16, galactitol 2-dehydrogenase).

The enzyme appears in viruses and cellular organisms

Synonyms
gatdh, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
galactitol + NAD+ = D-tagatose + NADH + H+
show the reaction diagram
galactitol + NAD+ = L-tagatose + NADH + H+
show the reaction diagram
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