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Information on EC 1.1.99.6 - D-lactate dehydrogenase (acceptor)

for references in articles please use BRENDA:EC1.1.99.6
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IUBMB Comments
The zinc flavoprotein (FAD) from the archaeon Archaeoglobus fulgidus cannot utilize NAD+, cytochrome c, methylene blue or dimethylnaphthoquinone as acceptors. In vitro it is active with artificial electron acceptors such as 2,6-dichlorophenolindophenol, but the physiological acceptor is not yet known.
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The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota
Synonyms
AF0394, APE_0487, D-2-hydroxy acid dehydrogenase, dehydrogenase, D-2-hydroxy acid, Dld enzyme, dye-linked D-lactate dehydrogenase, ST0649, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-lactate + acceptor = pyruvate + reduced acceptor
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PATHWAY SOURCE
PATHWAYS
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