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BRENDA support

Information on EC 1.1.99.6 - D-lactate dehydrogenase (acceptor)

for references in articles please use BRENDA:EC1.1.99.6

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IUBMB Comments

The zinc flavoprotein (FAD) from the archaeon Archaeoglobus fulgidus cannot utilize NAD+, cytochrome c, methylene blue or dimethylnaphthoquinone as acceptors. In vitro it is active with artificial electron acceptors such as 2,6-dichlorophenolindophenol, but the physiological acceptor is not yet known.

The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota

Synonyms
dye-dldh, d-2-hydroxy acid dehydrogenase, dye-linked d-lactate dehydrogenase, dld enzyme, af0394, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-lactate + acceptor = pyruvate + reduced acceptor
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS