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IUBMB CommentsHeme proteins with histidine as proximal ligand. The iron in the resting enzyme is Fe(III). They also peroxidize non-phenolic substrates such as 3,3',5,5'-tetramethylbenzidine (TMB) and 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS). Certain peroxidases (e.g. lactoperoxidase, SBP) oxidize bromide, iodide and thiocyanate.
Synonyms
horseradish peroxidase, horseradish peroxidase (hrp), rhepo, lactoperoxidase, eosinophil peroxidase, guaiacol peroxidase, heme peroxidase, rubrerythrin, cyp119, thiol peroxidase,
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anionic isoperoxidase
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anionic peroxidase A1
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black radish peroxidase A
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black radish peroxidase B
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cationic peroxidase Cs
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class III plant peroxidase
constitutive peroxidase
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-
donor: H2O2 oxidoreductase
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donor: hydrogen peroxide oxidoreductase
donor:hydrogen peroxide oxidoreductase
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extensin peroxidase
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-
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extracellular peroxidase
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-
guaiacol peroxidase
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-
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hemoglobin peroxidase
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as a hemoprotein, hemoglobin can, in the presence of H2O2, act as a peroxidase
hexacoordinate (class 1) non-symbiotic hemoglobin
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horseradisch peroxidase
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horseradish peroxidase (HRP)
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-
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horseradish peroxidase C
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HP
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acidic isoform, type A
HRP-C
isoenzyme C of horseradish peroxidase
HTHP
peroxidase and catalase activity
hydrogen donor oxidoreductase
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Japanese radish peroxidase
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-
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peroxidase isoenzyme E5
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protoheme peroxidase
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-
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pyrocatechol peroxidase
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-
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rhEPO
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recombinant human eosinophil peroxidase
rHRP1
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apo-horseradish peroxidase constituted with the artificial prostethic group heminD1
rHRP2
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apo-horseradish peroxidase constituted with the artificial prostethic group heminD2
royal palm tree peroxidase
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member of the class III peroxidases
scopoletin peroxidase
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-
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stigma-specific peroxidase
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thiocyanate peroxidase
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-
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tyrosine-coordinated heme protein
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vacuolar class III peroxidase
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versatile peroxidase VPL2
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BCcP
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cationic peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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class III plant peroxidase
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CmMnP
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cPOD-I
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isozyme
CYP119
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donor: hydrogen peroxide oxidoreductase
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donor: hydrogen peroxide oxidoreductase
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DtpA
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eosinophil peroxidase
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eosinophil peroxidase
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eosinophil peroxidase
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heme peroxidase
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horseradish peroxidase
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684412, 685761, 687940, 687953, 688317, 688465, 695576, 698432, 698475, 698486, 699011, 699769, 701263, 711160, 713517, 724400, 724412, 726432
horseradish peroxidase
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type VI
HRP
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659637, 684412, 685761, 687940, 688317, 688465, 695575, 695576, 696482, 696500, 698475, 698486, 699011, 699769, 701263, 711361, 712226, 713517, 724400, 724412, 726432, 741641
HRPC
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isoenzyme C
lactoperoxidase
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LPO
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MnP124076
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MnP13
gene name, UniProt
MnP13
gene name, UniProt
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MPO
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-
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myeloperoxidase
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-
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NGO_0994
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peroxidase
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POD
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Prx02
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isoform
Prx07
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isoform
Prx1
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isoform
Prx1
major class III peroxidase with anhydrovinblastine synthase activity
Prx60
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isoform
QPO
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quinol peroxidase
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rPOD-II
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isozyme
Saci_2081
locus name
SBP
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short PMnP
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thiol peroxidase
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Tpx
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Tpx
Tpx is an atypical 2-Cys peroxiredoxin
vascular peroxidase 1
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vascular peroxidase 1
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versatile peroxidase
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VPO1
isozyme
additional information
cf. EC 1.11.1.13
additional information
cf. EC 1.11.1.13
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phenolic donor:hydrogen-peroxide oxidoreductase
Heme proteins with histidine as proximal ligand. The iron in the resting enzyme is Fe(III). They also peroxidize non-phenolic substrates such as 3,3',5,5'-tetramethylbenzidine (TMB) and 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS). Certain peroxidases (e.g. lactoperoxidase, SBP) oxidize bromide, iodide and thiocyanate.
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(2Z)-2-(4-aminophenyl)-3-(1H-indol-2-yl)prop-2-enenitrile + H2O2
?
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-
-
-
?
(2Z)-2-(4-aminophenyl)-3-(4-hydroxyphenyl)prop-2-enenitrile + H2O2
?
-
-
-
-
?
(2Z)-2-(4-aminophenyl)-3-(9-ethyl-9H-carbazol-3-yl)prop-2-enenitrile + H2O2
?
-
-
-
-
?
(2Z)-2-(4-aminophenyl)-3-anthracen-9-ylprop-2-enenitrile + H2O2
?
-
-
-
-
?
(2Z)-2-(4-aminophenyl)-3-pyren-1-ylprop-2-enenitrile + H2O2
?
-
-
-
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?
(2Z)-2-(4-aminophenyl)-3-thiophen-2-ylprop-2-enenitrile + H2O2
?
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-
-
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?
(2Z)-3-(1H-indol-3-yl)-2-(4-nitrophenyl)prop-2-enenitrile + H2O2
?
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-
-
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?
(2Z)-3-(4-hydroxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile + H2O2
?
-
-
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?
(2Z)-3-[4-(dimethylamino)phenyl]-2-(4-nitrophenyl)prop-2-enenitrile + H2O2
?
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-
-
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?
(2Z,4E)-2-(4-aminophenyl)-5-[4-(dimethylamino)phenyl]penta-2,4-dienenitrile + H2O2
?
-
-
-
-
?
1-(1,3-dioxolan-2-ylmethyl)-4-[(E)-2-[4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]ethenyl]pyridinium bromide + H2O2
?
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-
-
-
?
1-(1,3-dioxolan-2-ylmethyl)-4-[(E)-2-[4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]ethenyl]pyridinium perchlorate + H2O2
?
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-
-
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?
1-butyl-4-[(E)-2-(1H-indol-3-yl)ethenyl]quinolinium perchlorate + H2O2
?
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-
-
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?
1-ethyl-4-[(E)-2-(1H-indol-3-yl)ethenyl]quinolinium iodide + H2O2
?
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-
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?
1-ethyl-4-[(E)-2-(1H-pyrrol-2-yl)ethenyl]quinolinium iodide + H2O2
?
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-
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?
1-ethyl-4-[(E)-2-thiophen-2-ylethenyl]quinolinium iodide + H2O2
?
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?
1-methyl-4-[(E)-2-(1H-pyrrol-2-yl)ethenyl]pyridinium iodide + H2O2
?
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-
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?
1-methyl-4-[(E)-2-thiophen-2-ylethenyl]pyridinium iodide + H2O2
?
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?
1-naphthol + H2O2
? + H2O
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peroxidase is inactived during oxidation
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?
2 guaiacol + H2O2
3,3'-dimethoxy-4,4'-biphenylquinone + H2O
2 K4[Fe(CN)6] + H2O2
K3[Fe(CN)6] + H2O + K2O
2 Mn(II) + 2 H+ + H2O2
2 Mn(III) + 2 H2O
2 phenol + 2 nitrite + H2O2
2 nitrophenol + H2O
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-
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?
2 pyrogallol + H2O2
? + H2O
2 veratryl alcohol + H2O2
2 veratraldehyde + H2O
2,2'-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) + H2O2
? + H2O
2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O2
?
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-
-
-
?
2,2'-azino-bis(3-ethylbenzthiazole-6-sulfonic acid) + H2O2
?
2,2'-azino-bis(3-ethylbenzthiazoline)-sulfonic acid + H2O2
?
2,2'-azino-bis-(3-ethyl-6-benzothiazolinsulfonate) + H2O2
?
100% activity
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?
2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) + (13S)-hydroperoxylinoleic acid
?
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-
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?
2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) + (5S)-hydroperoxyarachidonic acid
?
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-
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?
2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) + (8R)-hydroperoxyarachidonic acid
?
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-
-
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?
2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) + (9S)-hydroperoxylinoleic acid
?
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-
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?
2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) + cumene hydroperoxide
?
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-
-
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?
2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) + H2O2
?
2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) + tert-butyl hydroperoxide
?
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-
-
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?
2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) + H2O2
? + H2O
2,2'-methylene-bis[4-chlorophenol] + H2O2
4-chlorophenol-2,2'-methylene-1,4-benzoquinone + HCl
-
-
-
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?
2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt + H2O2
?
1.11.1.7 peroxidase
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