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Information on EC 1.12.2.1 - cytochrome-c3 hydrogenase

for references in articles please use BRENDA:EC1.12.2.1

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IUBMB Comments

An iron-sulfur protein. Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). Methylene blue and other acceptors can also be reduced.

The expected taxonomic range for this enzyme is: Bacteria, Archaea
Reaction Schemes

Synonyms
[nife] hydrogenase, [nife]-hydrogenase, [fefe] hydrogenase, [fe]-hydrogenase, [fe] hydrogenase, h2ase, fe-only hydrogenase, [nifese] hydrogenase, hydab, [nifese] hase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
H2 + 2 ferricytochrome c3 = 2 H+ + 2 ferrocytochrome c3
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
lactate fermentation to acetate, CO2 and hydrogen (Desulfovibrionales)