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IUBMB CommentsUses molecular hydrogen for the reduction of a variety of substances. Contains iron-sulfur clusters. The enzyme from some sources contains nickel.
The enzyme appears in viruses and cellular organisms
Synonyms
[fefe]-hydrogenase, uptake hydrogenase, hydrogenase 3, hyda1, hyd-1, fe-hydrogenase, hyd-2, hydrogenase 1, nife hydrogenase, hydrogenase 2,
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ECH
Megalodesulfovibrio gigas
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EchA
Megalodesulfovibrio gigas
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EchB
Megalodesulfovibrio gigas
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EchD
Megalodesulfovibrio gigas
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EchE
Megalodesulfovibrio gigas
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EchF
Megalodesulfovibrio gigas
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energy-converting hydrogenase
F420-reducing [NiFe] hydrogenase
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factor420 hydrogenase
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ferredoxin hydrogenase
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H2 producing hydrogenase [ambiguous]
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H2-sensing [NiFe] hydrogenase
HoxEFUYH type [NiFe] hydrogenase
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hydrogen dehydrogenase
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hydrogen uptake hydrogenase
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hydrogen-forming methylenetetrahydromethanopterin dehydrogenase
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hydrogen-lyase [ambiguous]
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hydrogen:ferredoxin oxidoreductase
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hydrogen:methylviologen oxidoreductase
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hydrogenase (ferredoxin)
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hydrogenase 1
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hydrogen uptake activity only
hydrogenase I (bidirectional)
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catalyzes H2 oxidation and reduction at similar rates
hydrogenase II (uptake)
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preferentially catalyzes H2 oxidation
hydrogenlyase [ambiguous]
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iron-sulfur-cluster-free hydrogenase
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membrane-bound [NiFe]-hydrogenase
methyl viologen-reducing hydrogenase
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methylviologen hydrogenase
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nickel-iron hydrogenase
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NiFe-hydrogenase
Solidesulfovibrio fructosivorans
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uptake hydrogenase [ambiguous]
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uptake [NiFe] hydrogenase:
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uptake [NiFe]-hydrogenase
[Fe]-hydA
Q2PWI0, Q2PWI3, Q2PWI4, Q2PWI5, Q2PWI6, Q2PWI7, Q2PWI9, Q2PWJ0, Q2PWJ8, Q38IH5, Q38IH6, Q38IH8, Q38IH9, Q38II3, Q38II4, Q38IJ1 -
[NiFe]H2ase
Megalodesulfovibrio gigas
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[NiFe]hydrogenase
Megalodesulfovibrio gigas
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endo-hydrogenase
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energy-converting hydrogenase
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energy-converting hydrogenase
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exo-hydrogenase
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H2-sensing [NiFe] hydrogenase
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H2-sensing [NiFe] hydrogenase
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HoxG
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HupB
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gene name, EC 1.12.99.6
HupB
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gene name, EC 1.12.99.6
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HupL
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HupL
Q84GM3; Q4G6A7
large subunit of uptake hydrogenase
HupL
Q84GM3; Q4G6A7
large subunit of uptake hydrogenase
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HupL
large subunit of uptake hydrogenase
HupL
large subunit of uptake hydrogenase
HupL
Thermosynechococcus vestitus
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HupS
Q84GM3; Q4G6A7
small subunit of uptake hydrogenase
HupS
Q84GM3; Q4G6A7
small subunit of uptake hydrogenase
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HupS
small subunit of uptake hydrogenase
HupS
small subunit of uptake hydrogenase
Hya
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HyC
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HycE
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Hyd-1
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Hyd-2
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Hyd-3
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Hyd-4
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hydA
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hydA
Q2PWI0, Q2PWI3, Q2PWI4, Q2PWI5, Q2PWI6, Q2PWI7, Q2PWI9, Q2PWJ0, Q2PWJ8, Q38IH5, Q38IH6, Q38IH8, Q38IH9, Q38II3, Q38II4, Q38IJ1 -
hydrogenase 2
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hydrogenase 2
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hydrogen uptake activity only
hydrogenase 3
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hydrogenase 3
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hydrogen uptake and synthesis activity
hydrogenase 3
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hydrogenase 3 is the large subunit of a [Ni-Fe]-type hydrogenase
hydrogenase 3
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hydrogenase 3 is the large subunit of a [Ni-Fe]-type hydrogenase
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hydrogenase II
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hydrogenase-1
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hydrogenase-2
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hydrogenases Hyd-1
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hydrogenases Hyd-2
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hyf
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Hyq
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Mbh
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membrane-bound [NiFe]-hydrogenase
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membrane-bound [NiFe]-hydrogenase
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Ni-Fe hydrogenase
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NiFe hydrogenase
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NiFe hydrogenase
Solidesulfovibrio fructosivorans
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NiFe(Se) hydrogenase
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NiFe(Se) hydrogenase
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NiFe(Se) hydrogenase
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regulatory hydrogenase
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regulatory hydrogenase
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respiratory hydrogenase
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respiratory hydrogenase
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respiratory hydrogenase
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respiratory hydrogenase
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SHI
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uptake hydrogenase
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uptake hydrogenase
Q84GM3; Q4G6A7
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uptake hydrogenase
Q84GM3; Q4G6A7
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uptake hydrogenase
Lyngbya sp.
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uptake hydrogenase
Thermosynechococcus vestitus
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uptake [NiFe]-hydrogenase
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uptake [NiFe]-hydrogenase
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[FeFe] hydrogenase
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[FeFe]-H2ase
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[FeFe]-hydrogenase
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[FeFe]H2ase
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[Fe]-hydrogenase
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[Fe]-hydrogenase
Q2PWI0, Q2PWI3, Q2PWI4, Q2PWI5, Q2PWI6, Q2PWI7, Q2PWI9, Q2PWJ0, Q2PWJ8, Q38IH5, Q38IH6, Q38IH8, Q38IH9, Q38II3, Q38II4, Q38IJ1 -
[Ni-Fe] hydrogenase
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[Ni-Fe] hydrogenase
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[NiFe] hydrogenase
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[NiFe] hydrogenase
Lyngbya sp.
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1.12.99.6 hydrogenase (acceptor)
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