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Information on EC 1.13.11.50 - acetylacetone-cleaving enzyme

for references in articles please use BRENDA:EC1.13.11.50

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IUBMB Comments

An iron(II)-dependent enzyme. Forms the first step in the acetylacetone degradation pathway of Acinetobacter johnsonii. While acetylacetone is by far the best substrate, heptane-3,5-dione, octane-2,4-dione, 2-acetylcyclohexanone and ethyl acetoacetate can also act as substrates.

The enzyme appears in viruses and cellular organisms

Synonyms
diketone cleaving enzyme, acetylacetone dioxygenase, diketone dioxygenase, acetylacetone-cleaving enzyme, diketone-cleaving dioxygenase, diketone cleaving dioxygenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
pentane-2,4-dione + O2 = acetate + 2-oxopropanal
show the reaction diagram
Highest Expressing Human Cell Lines
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