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Information on EC 1.13.11.66 - hydroquinone 1,2-dioxygenase

for references in articles please use BRENDA:EC1.13.11.66

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IUBMB Comments

The enzyme is an extradiol-type dioxygenase, and is a member of the nonheme-iron(II)-dependent dioxygenase family. It catalyses the ring cleavage of a wide range of hydroquinone substrates to produce the corresponding 4-hydroxymuconic semialdehydes.

The expected taxonomic range for this enzyme is: Bacteria, Archaea

Synonyms
pnpcd, hydroquinone dioxygenase, hydroquinone 1,2-dioxygenase, pdcde, two-subunit hydroquinone 1,2-dioxygenase, pnpc2, pnpc1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
benzene-1,4-diol + O2 = (2Z,4E)-4-hydroxy-6-oxohexa-2,4-dienoate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
4-hydroxyacetophenone degradation, 4-nitrophenol degradation I, pinoresinol degradation
Highest Expressing Human Cell Lines
Cell Line Links Gene Links