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Information on EC 1.13.11.72 - 2-hydroxyethylphosphonate dioxygenase

for references in articles please use BRENDA:EC1.13.11.72

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IUBMB Comments

Requires non-heme-Firon(II). Isolated from some bacteria including Streptomyces hygroscopicus and Streptomyces viridochromogenes. The pro-R hydrogen at C-2 of the ethyl group is retained by the formate ion. Any stereochemistry at C-1 of the ethyl group is lost. One atom from dioxygen is present in each product. Involved in phosphinothricin biosynthesis.

The enzyme appears in viruses and cellular organisms

Synonyms
hydroxyethylphosphonate dioxygenase, 2-hydroxyethylphosphonate dioxygenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-hydroxyethylphosphonate + O2 = hydroxymethylphosphonate + formate
show the reaction diagram
Highest Expressing Human Cell Lines
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