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Information on EC 1.14.11.35 - 1-deoxypentalenic acid 11beta-hydroxylase

for references in articles please use BRENDA:EC1.14.11.35

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IUBMB Comments

The enzyme requires Fe(II) and ascorbate. Isolated from the bacterium Streptomyces avermitilis. Part of the pathway for pentalenolactone biosynthesis.

The enzyme appears in viruses and cellular organisms

Synonyms
pntH, ptlH, sav2991, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1-deoxypentalenate + 2-oxoglutarate + O2 = 1-deoxy-11beta-hydroxypentalenate + succinate + CO2
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
neopentalenoketolactone and pentalenate biosynthesis, pentalenolactone biosynthesis
Highest Expressing Human Cell Lines
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