Reference on EC 1.14.11.68 - [histone H3]-trimethyl-L-lysine27 demethylase
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Na, J.; Lee, K.; Na, W.; Shin, J.; Lee, M.; Yune, T.; Lee, H.; Jung, H.; Kim, W.; Ju, B.
Histone H3K27 demethylase JMJD3 in cooperation with NF-kappaB regulates keratinocyte wound healing
J. Invest. Dermatol.
136
847-858
2016
Homo sapiens (O15054)
-
Shen, Y.; Guo, X.; Wang, Y.; Qiu, W.; Chang, Y.; Zhang, A.; Duan, X.
Expression and significance of histone H3K27 demethylases in renal cell carcinoma
BMC Cancer
12
470
2012
Homo sapiens (O15054), Homo sapiens (O15550)
De Santa, F.; Totaro, M.G.; Prosperini, E.; Notarbartolo, S.; Testa, G.; Natoli, G.
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
Cell
130
1083-1094
2007
Mus musculus (Q5NCY0)
Gao, J.; Gu, J.; Pan, X.; Gan, X.; Ju, Z.; Zhang, S.; Xia, Y.; Lu, L.; Wang, X.
Blockade of miR-142-3p promotes anti-apoptotic and suppressive function by inducing KDM6A-mediated H3K27me3 demethylation in induced regulatory T cells
Cell Death Dis.
10
332
2019
Homo sapiens (O15550), Homo sapiens
Burgold, T.; Voituron, N.; Caganova, M.; Tripathi, P.P.; Menuet, C.; Tusi, B.K.; Spreafico, F.; Bevengut, M.; Gestreau, C.; Buontempo, S.; Simeone, A.; Kruidenier, L.; Natoli, G.; Casola, S.; Hilaire, G.; Testa, G.
The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival
Cell Rep.
2
1244-1258
2012
Mus musculus (Q5NCY0)
Xiang, Y.; Zhu, Z.; Han, G.; Lin, H.; Xu, L.; Chen, C.D.
JMJD3 is a histone H3K27 demethylase
Cell Res.
17
850-857
2007
Homo sapiens (O15054)
Pan, D.; Huang, L.; Zhu, L.J.; Zou, T.; Ou, J.; Zhou, W.; Wang, Y.X2
Jmjd3-mediated H3K27me3 dynamics orchestrate brown fat development and regulate white fat plasticity
Dev. Cell
35
568-583
2015
Mus musculus (Q5NCY0)
Seenundun, S.; Rampalli, S.; Liu, Q.C.; Aziz, A.; Palii, C.; Hong, S.; Blais, A.; Brand, M.; Ge, K.; Dilworth, F.J.
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis
EMBO J.
29
1401-1411
2010
Mus musculus (O70546)
Svotelis, A.; Bianco, S.; Madore, J.; Huppe, G.; Nordell-Markovits, A.; Mes-Masson, A.M.; Gevry, N.
H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERalpha ligand dependency
EMBO J.
30
3947-3961
2011
Homo sapiens
Kamikawa, Y.F.; Donohoe, M.E.
The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated
Epigenetics
9
834-841
2014
Homo sapiens (O15054), Mus musculus (Q5NCY0)
Sengoku, T.; Yokoyama, S.
Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
Genes Dev.
25
2266-2277
2011
Homo sapiens (O15550)
Chen, S.; Ma, J.; Wu, F.; Xiong, L.J.; Ma, H.; Xu, W.; Lv, R.; Li, X.; Villen, J.; Gygi, S.P.; Liu, X.S.; Shi, Y.
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation
Genes Dev.
26
1364-1375
2012
Homo sapiens (O15054)
Chen, Y.; Liu, Z.; Pan, T.; Chen, E.; Mao, E.; Chen, Y.; Tan, R.; Wang, X.; Tian, R.; Liu, J.; Qu, H.
JMJD3 is involved in neutrophil membrane proteinase 3 overexpression during the hyperinflammatory response in early sepsis
Int. Immunopharmacol.
59
40-46
2018
Homo sapiens (O15054)
Kawaguchi, A.; Ochi, H.; Sudou, N.; Ogino, H.
Comparative expression analysis of the H3K27 demethylases, JMJD3 and UTX, with the H3K27 methylase, EZH2, in Xenopus
Int. J. Dev. Biol.
56
295-300
2012
Xenopus tropicalis (K9K8P2)
Li, Y.; Quan, X.; Li, X.; Pan, Y.; Zhang, T.; Liang, Z.; Wang, Y.
Kdm6A protects against hypoxia-induced cardiomyocyte apoptosis via H3K27me3 demethylation of Ncx gene
J. Cardiovasc. Transl. Res.
12
488-495
2019
Rattus norvegicus (A0A0G2K6D0)
Liu, Z.; Cao, W.; Xu, L.; Chen, X.; Zhan, Y.; Yang, Q.; Liu, S.; Chen, P.; Jiang, Y.; Sun, X.; Tao, Y.; Hu, Y.; Li, C.; Wang, Q.; Wang, Y.; Chen, C.D.; Shi, Y.; Zhang, X.
The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation
J. Mol. Cell Biol.
7
505-516
2015
Mus musculus (Q5NCY0)
Messer, H.G.; Jacobs, D.; Dhummakupt, A.; Bloom, D.C.
Inhibition of H3K27me3-specific histone demethylases JMJD3 and UTX blocks reactivation of herpes simplex virus 1 in trigeminal ganglion neurons
J. Virol.
89
3417-3420
2015
Mus musculus (O70546), Mus musculus (Q5NCY0)
Manna, S.; Kim, J.; Bauge, C.; Cam, M.; Zhao, Y.; Shetty, J.; Vacchio, M.; Castro, E.; Tran, B.; Tessarollo, L.; Bosselut, R.
Histone H3 lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation
Nat. Commun.
6
8152
2015
Mus musculus (Q5NCY0)
Lan, F.; Bayliss, P.E.; Rinn, J.L.; Whetstine, J.R.; Wang, J.K.; Chen, S.; Iwase, S.; Alpatov, R.; Issaeva, I.; Canaani, E.; Roberts, T.M.; Chang, H.Y.; Shi, Y.
A histone H3 lysine 27 demethylase regulates animal posterior development
Nature
449
689-694
2007
Danio rerio (A1L1S9), Homo sapiens (O15550)
Agger, K.; Cloos, P.A.; Christensen, J.; Pasini, D.; Rose, S.; Rappsilber, J.; Issaeva, I.; Canaani, E.; Salcini, A.E.; Helin, K.
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
Nature
449
731-734
2007
Homo sapiens (O15054), Homo sapiens (O15550), Homo sapiens, Caenorhabditis elegans (Q95QK3), Caenorhabditis elegans
Shpargel, K.B.; Starmer, J.; Yee, D.; Pohlers, M.; Magnuson, T.
KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development
PLoS Genet.
10
e1004507
2014
Mus musculus (O70546), Mus musculus (Q5NCY0)
Burgold, T.; Spreafico, F.; De Santa, F.; Totaro, M.; Prosperini, E.; Natoli, G.; Testa, G.
The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment
PLoS ONE
3
e3404
2008
Mus musculus (Q5NCY0)
Das, N.; Jung, K.; Chai, Y.
The role of NF-kappaB and H3K27me3 demethylase, Jmjd3, on the anthrax lethal toxin tolerance of RAW 264.7 cells
PLoS ONE
5
e9913
2010
Mus musculus (Q5NCY0)
Iwamori, N.; Iwamori, T.; Matzuk, M.M.
H3K27 demethylase, JMJD3, regulates fragmentation of spermatogonial cysts
PLoS One
8
e72689
2013
Mus musculus (Q5NCY0)
Hong, S.; Cho, Y.W.; Yu, L.R.; Yu, H.; Veenstra, T.D.; Ge, K.
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
Proc. Natl. Acad. Sci. USA
104
18439-18444
2007
Homo sapiens (O15550)
Lee, M.G.; Villa, R.; Trojer, P.; Norman, J.; Yan, K.P.; Reinberg, D.; Di Croce, L.; Shiekhattar, R.
Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
Science
318
447-450
2007
Homo sapiens (O15550)
Guo, X.; Zhang, Y.; Zhang, Q.; Fa, P.; Gui, Y.; Gao, G.; Cai, Z.
The regulatory role of nickel on H3K27 demethylase JMJD3 in kidney cancer cells
Toxicol. Ind. Health
32
1286-92
2016
Homo sapiens (O15054)
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