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Information on EC 1.14.13.166 - 4-nitrocatechol 4-monooxygenase

for references in articles please use BRENDA:EC1.14.13.166

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IUBMB Comments

Contains FAD. The enzyme catalyses the oxidation of 4-nitrocatechol with the concomitant removal of the nitro group as nitrite. Forms a two-component system with a flavoprotein reductase . The enzymes from the bacteria Lysinibacillus sphaericus JS905 and Rhodococcus sp. strain PN1 were shown to also catalyse EC 1.14.13.29, 4-nitrophenol 2-monooxygenase [1,2] while the enzyme from Pseudomonas sp. WBC-3 was shown to also catalyse EC 1.14.13.167, 4-nitrophenol 4-monooxygenase .

The enzyme appears in viruses and cellular organisms

Synonyms
pnp 4-monooxygenase, npda2, p-nitrophenol monooxygenase, para-nitrophenol 4-monooxygenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-nitrocatechol + NAD(P)H + H+ + O2 = 2-hydroxy-1,4-benzoquinone + nitrite + NAD(P)+ + H2O
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
4-nitrophenol degradation II
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