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Information on EC 1.14.13.215 - protoasukamycin 4-monooxygenase

for references in articles please use BRENDA:EC1.14.13.215
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IUBMB Comments
The enzyme, characterized from the bacterium Streptomyces nodosus subsp. asukaensis, is involved in the biosynthesis of the antibiotic asukamycin. Requires a flavin cofactor, with no preference among FMN, FAD or riboflavin. When flavin concentration is low, activity is enhanced by the presence of the NADH-dependent flavin-reductase AsuE2.
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The expected taxonomic range for this enzyme is: Streptomyces nodosus
Synonyms
asue1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
protoasukamycin + NADH + H+ + O2 = 4-hydroxyprotoasukamycin + NAD+ + H2O
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