Information on EC 1.14.14.50 - tabersonine 3-oxygenase

for references in articles please use BRENDA:EC1.14.14.50
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The expected taxonomic range for this enzyme is: Catharanthus roseus

EC NUMBER
COMMENTARY hide
1.14.14.50
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RECOMMENDED NAME
GeneOntology No.
tabersonine 3-oxygenase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
16-methoxytabersonine + [reduced NADPH-hemoprotein reductase] + O2 = (3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
(1)
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-
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tabersonine + [reduced NADPH-hemoprotein reductase] + O2 = (3R)-3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
(2)
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-
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
vindoline and vinblastine biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
16-methoxytabersonine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (3-hydroxylating)
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
cultivar Little Delicata
UniProt
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
16-methoxytabersonine + [reduced NADPH-hemoprotein reductase] + O2
(3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
tabersonine + [reduced NADPH-hemoprotein reductase] + O2
(3R)-3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE