Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 1.14.14.79 - docosahexaenoic acid omega-hydroxylase

for references in articles please use BRENDA:EC1.14.14.79

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

A cytochrome P-450 (heme-thiolate) protein isolated from human eye tissue. Defects in the enzyme are associated with Bietti crystalline corneoretinal dystrophy. The enzyme also produces some 21-hydroxydocosahexaenoate. Acts in a similar way on icosapentaenoic acid.

The enzyme appears in viruses and cellular organisms
  • 1.14.14.79
  • dystrophy
  • bietty
  • retinal
  • corneoretinal
  • fundus
  • acuity
  • chorioretinal
  • electroretinography
  • limbus
  • full-field
  • intraretinal
  • hyperreflective
  • glittering
  • serpinc1
  • perimetry
  • crystalline-like
  • choriocapillaris
  • crystal-like
  • cyp4z1

Synonyms
cyp4v2, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
docosahexaenoate + [reduced NADPH-hemoprotein reductase] + O2 = 22-hydroxydocosahexaenoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
-
Highest Expressing Human Cell Lines
Cell Line Links Gene Links