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Information on EC 1.14.14.86 - ent-kaurene monooxygenase

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IUBMB Comments
Requires cytochrome P-450. Catalyses three sucessive oxidations of the 4-methyl group of ent-kaurene giving kaurenoic acid.
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The enzyme appears in viruses and cellular organisms
Synonyms
ent-kaurene oxidase, p450-4, osko2, cyp701b1, cyp701a, kaurene oxidase, cyp701a26, psko1, cyp701, cyp701a6, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ent-kaur-16-en-19-al + [reduced NADPH-hemoprotein reductase] + O2 = ent-kaur-16-en-19-oate + [oxidized NADPH-hemoprotein reductase] + H2O
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(1c)
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ent-kaur-16-en-19-ol + [reduced NADPH-hemoprotein reductase] + O2 = ent-kaur-16-en-19-al + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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(1b)
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ent-kaur-16-ene + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 = ent-kaur-16-en-19-oate + 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O
show the reaction diagram
ent-kaur-16-ene + [reduced NADPH-hemoprotein reductase] + O2 = ent-kaur-16-en-19-ol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
(1a)
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