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Information on EC 1.14.14.89 - 4'-methoxyisoflavone 2'-hydroxylase

for references in articles please use BRENDA:EC1.14.14.89
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IUBMB Comments
A heme-thiolate protein (P-450). Acts on isoflavones with a 4'-methoxy group, such as formononetin and biochanin A. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. EC 1.14.13.89, isoflavone 2'-hydroxylase, is less specific and acts on other isoflavones as well as 4'-methoxyisoflavones.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
daidzein and genistein reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
formononetin + [reduced NADPH-hemoprotein reductase] + O2 = 2'-hydroxyformononetin + [oxidized NADPH-hemoprotein reductase] + H2O
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