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Information on EC 1.14.14.90 - isoflavone 2'-hydroxylase

for references in articles please use BRENDA:EC1.14.14.90
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IUBMB Comments
A heme-thiolate protein (P-450). Acts on daidzein, formononetin and genistein. EC 1.14.13.53, 4'-methoxyisoflavone 2'-hydroxylase, has the same reaction but is more specific as it requires a 4'-methoxyisoflavone.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
ami2'h, cyp81e1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an isoflavone + [reduced NADPH-hemoprotein reductase] + O2 = a 2'-hydroxyisoflavone + [oxidized NADPH-hemoprotein reductase] + H2O
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