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Information on EC 1.14.19.67 - salutaridine synthase

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IUBMB Comments
A heme-thiolate enzyme (P-450). Forms the morphinan alkaloid salutaridine by intramolecular phenol oxidation of reticuline without the incorporation of oxygen into the product.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
pssas, cyp719b1, salsyn, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 = salutaridine + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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