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Information on EC 1.18.1.3 - ferredoxin-NAD+ reductase

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IUBMB Comments
Contains FAD. Reaction (1) is written for a [2Fe-2S] ferredoxin, which is characteristic of some mono- and dioxygenase systems. The alternative reaction (2) is written for a 2[4Fe-4S] ferredoxin, which transfers two electrons, and occurs in metabolism of anaerobic bacteria.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
reduced 2[4Fe-4S] ferredoxin
+
+
=
oxidized 2[4Fe-4S] ferredoxin
+
Synonyms
bpha4, nadh-ferredoxin reductase, nadh-ferredoxin oxidoreductase, palustrisredoxin reductase, nadh-dependent ferredoxin reductase, ferredoxin-nad reductase, ferredoxin nadph reductase, ferredoxin-reductase, ferredoxin:nad+ oxidoreductase, ferredoxin-nadh oxidoreductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 reduced [2Fe-2S] ferredoxin + NAD+ + H+ = 2 oxidized [2Fe-2S] ferredoxin + NADH
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(1)
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reduced 2[4Fe-4S] ferredoxin + NAD+ + H+ = oxidized 2[4Fe-4S] ferredoxin + NADH
show the reaction diagram
(2)
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-
PATHWAY SOURCE
PATHWAYS
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