Reference on EC 1.2.1.104 - pyruvate dehydrogenase system
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Reed, L.J.; Yeaman, S.J.
Pyruvate dehydrogenase
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
18
77-95
1987
Bos taurus
-
Reed, L.J.; Damuni, Z.; Merryfield, M.L.
Regulation of mammalian pyruvate and branched-chain alpha-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation
Curr. Top. Cell. Regul.
27
41-49
1985
Bos taurus
Roche, T.E.; Cate, R.L.
Purification of porcine liver pyruvate dehydrogenase complex and characterization of its catalytic and regulatory properties
Arch. Biochem. Biophys.
183
664-677
1977
Sus scrofa
Linn, T.C.; Pelley, J.W.; Pettit, F.H.; Hucho, F.; Randall, D.D.; Reed, L.J.
alpha-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart
Arch. Biochem. Biophys.
148
327-342
1972
Bos taurus
Hiromasa, Y.; Aso, Y.; Yamashita, S.
Purification of pyruvate dehydrogenase complex from an extreme thermophile, Bacillus caldolyticus, and its thermal stability
Biosci. Biotechnol. Biochem.
57
1062-1066
1993
[Bacillus] caldolyticus
Yeaman, S.J.
The mammalian 2-oxoacid dehydrogenases: a complex family
Trends Biochem. Sci.
11
293-296
1986
Bos taurus, Sus scrofa
-
Severin, S.E.; Khailova, L.S.; Gomazkova, V.S.
Dehydrogenases of alpha-keto acids: essential groups of the active centers
Adv. Enzyme Regul.
25
347-375
1986
Pigeon
Randle, P.J.
Pyruvate dehydrogenase complex - meticulous regulator of glucose disposal in animals
Trends Biochem. Sci.
3
217-218
1978
Sus scrofa
-
Reed, L.J.; Cox, D.J.
Multienzyme complexes
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
1
213-240
1970
Bos taurus, Escherichia coli, Sus scrofa
-
Russell, G.C.; Guest, J.R.
Overexpression of restructured pyruvate dehydrogenase complexes and site-directed mutagenesis of a potential active-site histidine residue
Biochem. J.
269
443-450
1990
Escherichia coli
Budde, R.J.A.; Randall, D.D.
Pea leaf mitochondrial pyruvate dehydrogenase complex is inactivated in vivo in a light-dependent manner
Proc. Natl. Acad. Sci. USA
87
673-676
1990
Pisum sativum
Koike, K.; Urata, Y.; Koike, M.
Molecular cloning and characterization of human pyruvate dehydrogenase beta subunit gene
Proc. Natl. Acad. Sci. USA
87
5594-5597
1990
Homo sapiens
Flournoy, D.S.; Frey, P.A.
Inactivation of the pyruvate dehydrogenase complex of Escherichia coli by fluoropyruvate
Biochemistry
28
9594-9602
1989
Escherichia coli
Rapp, B.J.; Miernyk, J.A.; Randall, D.D.
Pyruvate dehydrogenase complexes from Ricinus communis endosperm
J. Plant Physiol.
127
293-306
1987
Bos taurus, Ricinus communis
-
Miernyk, J.A.; Randall, D.D.
Some kinetic and regulatory properties of the pea mitochondrial pyruvate dehydrogenase complex
Plant Physiol.
83
306-310
1987
Pisum sativum
Matuda, S.; Nakano, K.; Uraguchi, Y.; Matuo, S.; Saheki, T.
Immunological identification of a new component of Ascaris pyruvate dehydrogenase complex
Biochim. Biophys. Acta
926
54-60
1987
Ascaris sp.
Phelps, A.; Lindsay, J.G.
Mammalian pyruvate dehydrogenase complex binds tightly to the mitochondrial inner membrane
Biochem. Soc. Trans.
14
893
1986
Bos taurus
-
Treede, J.; Heise, K.P.
Purification of the chloroplast pyruvate dehydrogenase complex from spinach and maize mesophyll
Z. Naturforsch. C
41
1011-1017
1986
Pisum sativum, Spinacia oleracea, Zea mays
-
Gathercole, P.S.; Thiel, P.G.; Hofmeyr, H.S.
Inhibition of pyruvate dehydrogenase complex by moniliformin
Biochem. J.
233
719-723
1986
Bos taurus
Butler, M.H.; Mell, G.P.; Wright, B.E.
The pyruvate dehydrogenase complex in Dictyostelium discoideum
Curr. Top. Cell. Regul.
26
337-346
1985
Dictyostelium discoideum
De Kok, A.; Westphal, A.H.
Hybrid pyruvate dehydrogenase complexes reconstituted from components of the complexes from Escherichia coli and Azotobacter vinelandii
Eur. J. Biochem.
152
35-41
1985
Azotobacter vinelandii, Escherichia coli
Yang, H.; Hainfeld, J.F.; Wall, J.S.; Frey, P.A.
Quaternary structure of pyruvate dehydrogenase complex from Escherichia coli
J. Biol. Chem.
260
16049-16051
1985
Escherichia coli
CaJacob, C.A.; Gavino, G.R.; Frey, P.A.
Pyruvate dehydrogenase complex of Escherichia coli. Thiamin pyrophosphate and NADH-dependent hydrolysis of acetyl-CoA
J. Biol. Chem.
260
14610-14615
1985
Escherichia coli
Wu, T.L.; Reed, L.J.
Subunit binding in the pyruvate dehydrogenase complex from bovine kidney and heart
Biochemistry
23
221-226
1984
Bos taurus
Bosma, H.J.; de Kok, A.; Westphal, A.H.; Veeger, C.
The composition of the pyruvate dehydrogenase complex from Azotobacter vinelandii. Does a unifying model exist for the complexes from gram-negative bacteria?
Eur. J. Biochem.
142
541-549
1984
Azotobacter vinelandii
Matuda, S.; Shirahama, T.; Saheki, T.; Miura, S.; Mori, M.
Purification and immunochemical studies of pyruvate dehydrogenase complex from rat heart, and cell-free synthesis of lipoamide dehydrogenase, a component of the complex
Biochim. Biophys. Acta
741
86-93
1983
Rattus norvegicus
Lowe, P.N.; Hodgson, J.A.; Perham, R.N.
Dual role of a single multienzyme complex in the oxidative decarboxylation of pyruvate and branched-chain 2-oxo acids in Bacillus subtilis
Biochem. J.
215
133-140
1983
Bacillus subtilis
Horn, F.; Bisswanger, H.
Regulatory properties of the pyruvate dehydrogenase complex from Escherichia coli. Studies on the thiamine diphosphate-dependent lag phase
J. Biol. Chem.
258
6912-6919
1983
Escherichia coli
Hodgson, J.A.; Lowe, P.N.; Perham, R.N.
Wild-type and mutant forms of the pyruvate dehydrogenase multienzyme complex from Bacillus subtilis
Biochem. J.
211
463-472
1983
Bacillus subtilis
Jaenicke, R.; Perham, R.N.
Reconstitution of the pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus
Biochemistry
21
3378-3385
1982
Geobacillus stearothermophilus
Keha, E.E.; Ronft, H.; Kresze, G.B.
On the origin of mitochondria: a reexamination of the molecular structure and kinetic properties of pyruvate dehydrogenase complex from brewers yeast
FEBS Lett.
145
289-292
1982
Saccharomyces pastorianus
Seckler, R.; Binder, R.; Bisswanger, H.
Purification and properties of the pyruvate dehydrogenase complex from Salmonella typhimurium and formation of hybrids with the enzyme complex from Escherichia coli
Biochim. Biophys. Acta
705
210-217
1982
Salmonella enterica subsp. enterica serovar Typhimurium
Furuta, S.; Hashimoto, T.
Pyruvate dehydrogenase complex from pigeon breast muscle
Methods Enzymol.
89
414-420
1982
Pigeon
Visser, J.; Kester, H.; Jeyaseelan, K.; Topp, R.
Pyruvate dehydrogenase complex from Bacillus
Methods Enzymol.
89
399-407
1982
Geobacillus stearothermophilus, [Bacillus] caldolyticus, [Bacillus] caldotenax, Bacillus subtilis
Visser, J.; Sirating, M.
Pyruvate dehydrogenase complex from Escherichia coli
Methods Enzymol.
89
391-399
1982
Escherichia coli
Harding, R.W.; Caroline, D.F.; Wagner, R.P.
Pyruvate dehydrogenase complex from Neurospora
Methods Enzymol.
89
386-391
1982
Neurospora crassa
Bisswanger, H.
Substrate specificity of the pyruvate dehydrogenase complex from Escherichia coli
J. Biol. Chem.
256
815-822
1981
Escherichia coli
Reed, L.J.
Regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle
Curr. Top. Cell. Regul.
18
95-106
1981
Bos taurus
Kresze, G.B.; Ronft, H.
Pyruvate dehydrogenase complex from bakers yeast. 1. Purification and some kinetic and regulatory properties
Eur. J. Biochem.
119
573-579
1981
Saccharomyces cerevisiae
Kresze, G.B.; Ronft, H.
Pyruvate dehydrogenase complex from bakers yeast. 2. Molecular structure, dissociation, and implications for the origin of mitochondria
Eur. J. Biochem.
119
581-587
1981
Saccharomyces cerevisiae
Jeyaseelan, K.; Guest, J.R.; Visser, J.
The pyruvate dehydrogenase complex of Pseudomonas aeruginosa PAO. Purification, properties and characterization of mutants
J. Gen. Microbiol.
120
393-402
1980
Pseudomonas aeruginosa
Lazo, P.A.; Sols, A.
Pyruvate dehydrogenase complex of ascites tumour. Activation by AMP and other properties of potential significance in metabolic regulation
Biochem. J.
190
705-710
1980
Bos taurus, Homo sapiens, Mus musculus
Visser, J.; Kester, H.; Huigen, A.
Purification and some properties of the pyruvate dehydrogenase complex of Bacillus subtilis
FEMS Microbiol. Lett.
9
227-232
1980
Bacillus subtilis
-
Henderson, C.E.; Perham, R.N.
Purificaton of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus and resolution of its four component polypeptides
Biochem. J.
189
161-172
1980
Geobacillus stearothermophilus
Angelides, K.J.; Akiyama, S.K.; Hammes, G.C.
Subunit stoichiometry and molecular weight of the pyruvate dehydrogenase multienzyme complex from Escherichia coli
Proc. Natl. Acad. Sci. USA
76
3279-3283
1979
Escherichia coli
Danson, M.J.; Hale, G.; Johnson, P.; Perham, R.N.
Molecular weight and symmetry of the pyruvate dehydrogenase multienzyme complex of Escherichia coli
J. Mol. Biol.
129
603-617
1979
Escherichia coli
Rubin, P.M.; Zahler, W.L.; Randall, D.D.
Plant pyruvate dehydrogenase complex: analysis of the kinetic properties and metabolite regulation
Arch. Biochem. Biophys.
188
70-77
1978
Brassica oleracea
Rubin, P.M.; Randall, D.D.
Purification and characterization of pyruvate dehydrogenase complex from broccoli floral buds
Arch. Biochem. Biophys.
178
342-349
1977
Brassica oleracea
Luderitz, R.; Klemme, J.H.
Isolierung und Charakterisierung eines membrangebundenen Pyruvatdehydrogenase-Komplexes aus dem phototrophen Bakterium Rhodospirillum rubrum
Z. Naturforsch. C
32
351-361
1977
Rhodospirillum rubrum
Randall, D.D.; Rubin, P.M.; Fenko, M.
Plant pyruvate dehydrogenase complex purification, characterization and regulation by metabolites and phosphorylation
Biochim. Biophys. Acta
485
336-349
1977
Brassica oleracea
Bresters, T.W.; de Abreu, R.A.; de Kok, A.; Visser, J.; Veeger, C.
The pyruvate-dehydrogenase complex from Azotobacter vinelandii
Eur. J. Biochem.
59
335-345
1975
Azotobacter vinelandii, Escherichia coli, Sus scrofa
Wais, U.; Gillmann, U.; Ullrich, J.
Isolation and characterization of pyruvate dehydrogenase complex from brewer's yeast
Hoppe-Seyler's Z. Physiol. Chem.
345
1378-1388
1973
Saccharomyces pastorianus
Hirabayashi, T.; Harada, T.
Isolation and properties of a pyruvate dehydrogenase complex from the yeast Hansenula miso
J. Biochem.
71
797-804
1972
Hansenula miso
Harding, R.W.; Caroline, D.F.; Wagner, R.P.
The pyruvate dehydrogenase complex from the mitochondrial fraction of Neurospora crassa
Arch. Biochem. Biophys.
138
653-661
1970
Neurospora crassa
Guest, J.R.; Darlison, M.G.; Spencer, M.E.; Stephens, P.E.
Cloning and sequence analysis of the pyruvate and 2-oxoglutarate dehydrogenase complex genes of Escherichia coli
Biochem. Soc. Trans.
12
220-223
1984
Escherichia coli
Millar, A.H.; Knorpp, C.; Leaver, C.J.; Hill, S.A.
Plant mitochondrial pyruvate dehydrogenase complex: purification and identification of catalytic components in potato
Biochem. J.
334
571-576
1998
Solanum tuberosum (P52903)
Witzmann, S.; Bisswanger, H.
The pyruvate dehydrogenase complex from thermophilic organisms: thermal stability and re-association from the enzyme components
Biochim. Biophys. Acta
1385
341-352
1998
Geobacillus stearothermophilus, [Bacillus] caldolyticus, Thermus thermophilus
Neveling, U.; Klasen, R.; Bringer-Meyer, S.; Sahm, H.
Purification of the pyruvate dehydrogenase multienzyme complex of Zymomonas mobilis and identification and sequence analysis of the corresponding genes
J. Bacteriol.
180
1540-1548
1998
Zymomonas mobilis
Thelen, J.J.; Miernyk, J.A.; Randall, D.D.
Partial purification and characterization of the maize mitochondrial pyruvate dehydrogenase complex
Plant Physiol.
116
1443-1450
1998
Zea mays
Jones, D.D.; Horne, H.J.; Reche, P.A.; Perham, R.N.
Structural determinants of post-translational modification and catalytic specificity for the lipoyl domains of the pyruvate dehydrogenase multienzyme complex of Escherichia coli
J. Mol. Biol.
295
289-306
2000
Escherichia coli
Fast, N.M.; Keeling, P.J.
Alpha and beta subunits of pyruvate dehydrogenase E1 from the microsporidian Nosema locustae: mitochondrion-derived carbon metabolism in microsporidia
Mol. Biochem. Parasitol.
117
201-209
2001
Antonospora locustae
Liu, S.; Gong, X.; Yan, X.; Peng, T.; Baker, J.C.; Li, L.; Robben, P.M.; Ravindran, S.; Andersson, L.A.; Cole, A.B.; Roche, T.E.
Reaction Mechanism for Mammalian Pyruvate Dehydrogenase Using Natural Lipoyl Domain Substrates
Arch. Biochem. Biophys.
386
123-135
2001
Mammalia
Jung, H.I.; Cooper, A.; Perham, R.N.
Identification of key amino acid residues in the assembly of enzymes into the pyruvate dehydrogenase complex of Bacillus stearothermophilus: a kinetic and thermodynamic analysis
Biochemistry
41
10446-10453
2002
Geobacillus stearothermophilus
Jiang, X.R.; Dryhurst, G.
Inhibition of the alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase complexes by a putative aberrant metabolite of serotonin, tryptamine-4,5-dione
Chem. Res. Toxicol.
15
1242-1247
2002
Rattus norvegicus
Hiromasa, Y.; Fujisawa, T.; Aso, Y.; Roche, T.E.
Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components
J. Biol. Chem.
279
6921-6933
2004
Bos taurus
Strumilo, S.; Czygier, M.; Kondracikowska, J.; Dobrzyn, P.; Czerniecki, J.
Kinetic and spectral investigation of allosteric interaction of coenzymes with 2-oxo acid dehydrogenase complexes
J. Mol. Struct.
614
221-226
2002
Bos taurus
-
Sharma, N.; Okere, I.C.; Brunengraber, D.Z.; McElfresh, T.A.; King, K.L.; Sterk, J.P.; Huang, H.; Chandler, M.P.; Stanley, W.C.
Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation
J. Physiol.
562
593-603
2005
Sus scrofa
Jung, H.I.; Cooper, A.; Perham, R.N.
Interactions of the peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus
Eur. J. Biochem.
270
4488-4496
2003
Geobacillus stearothermophilus
Koukourakis, M.I.; Giatromanolaki, A.; Sivridis, E.; Gatter, K.C.; Harris, A.L.
Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma
Neoplasia
7
1-6
2005
Homo sapiens
Liu, X.; Bisswanger, H.
Interaction of thiamin diphosphate with phosphorylated and dephosphorylated mammalian pyruvate dehydrogenase complex
Biol. Chem.
386
11-18
2005
Bos taurus
Nemeria, N.S.; Korotchkina, L.G.; Chakraborty, S.; Patel, M.S.; Jordan, F.
Acetylphosphinate is the most potent mechanism-based substrate-like inhibitor of both the human and Escherichia coli pyruvate dehydrogenase components of the pyruvate dehydrogenase complex
Bioorg. Chem.
34
362-379
2006
Escherichia coli, Homo sapiens
Smolle, M.; Prior, A.E.; Brown, A.E.; Cooper, A.; Byron, O.; Lindsay, J.G.
A new level of architectural complexity in the human pyruvate dehydrogenase complex
J. Biol. Chem.
281
19772-19780
2006
Homo sapiens
Milne, J.L.; Wu, X.; Borgnia, M.J.; Lengyel, J.S.; Brooks, B.R.; Shi, D.; Perham, R.N.; Subramaniam, S.
Molecular structure of a 9-MDa icosahedral pyruvate dehydrogenase subcomplex containing the E2 and E3 enzymes using cryoelectron microscopy
J. Biol. Chem.
281
4364-4370
2006
Geobacillus stearothermophilus
Korotchkina, L.G.; Sidhu, S.; Patel, M.S.
Characterization of testis-specific isoenzyme of human pyruvate dehydrogenase
J. Biol. Chem.
281
9688-9696
2006
Homo sapiens
Foth, B.J.; Stimmler, L.M.; Handman, E.; Crabb, B.S.; Hodder, A.N.; McFadden, G.I.
The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast
Mol. Microbiol.
55
39-53
2005
Plasmodium falciparum
Jan, A.; Nakamura, H.; Handa, H.; Ichikawa, H.; Matsumoto, H.; Komatsu, S.
Gibberellin regulates mitochondrial pyruvate dehydrogenase activity in rice
Plant Cell Physiol.
47
244-253
2006
Oryza sativa
Bradley, N.S.; Heigenhauser, G.J.; Roy, B.D.; Staples, E.M.; Inglis, J.G.; LeBlanc, P.J.; Peters, S.J.
The acute effects of differential dietary fatty acids on human skeletal muscle pyruvate dehydrogenase activity
J. Appl. Physiol.
104
1-9
2008
Homo sapiens
McFate, T.; Mohyeldin, A.; Lu, H.; Thakar, J.; Henriques, J.; Halim, N.D.; Wu, H.; Schell, M.J.; Tsang, T.M.; Teahan, O.; Zhou, S.; Califano, J.A.; Jeoung, N.H.; Harris, R.A.; Verma, A.
Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells
J. Biol. Chem.
283
22700-22708
2008
Homo sapiens
Gey, U.; Czupalla, C.; Hoflack, B.; Roedel, G.; Krause-Buchholz, U.
Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases
J. Biol. Chem.
283
9759-9767
2008
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Yu, X.; Hiromasa, Y.; Tsen, H.; Stoops, J.K.; Roche, T.E.; Zhou, Z.H.
Structures of the human pyruvate dehydrogenase complex cores: a highly conserved catalytic center with flexible N-terminal domains
Structure
16
104-114
2008
Homo sapiens
Sidhu, S.; Gangasani, A.; Korotchkina, L.G.; Suzuki, G.; Fallavollita, J.A.; Canty, J.M.; Patel, M.S.
Tissue-specific pyruvate dehydrogenase complex deficiency causes cardiac hypertrophy and sudden death of weaned male mice
Am. J. Physiol. Heart Circ. Physiol.
295
H946-H952
2008
Mus musculus
Richards, J.G.; Sardella, B.A.; Schulte, P.M.
Regulation of pyruvate dehydrogenase in the common killifish, Fundulus heteroclitus, during hypoxia exposure
Am. J. Physiol. Regul. Integr. Comp. Physiol.
295
R979-R990
2008
Fundulus heteroclitus
Castro, M.E.; Molina, R.C.; Diaz, W.A.; Pradenas, G.A.; Vasquez, C.C.
Expression of Aeromonas caviae ST pyruvate dehydrogenase complex components mediate tellurite resistance in Escherichia coli
Biochem. Biophys. Res. Commun.
380
148-152
2009
Aeromonas caviae, Aeromonas caviae ST
Ostergaard, E.; Moller, L.B.; Kalkanoglu-Sivri, H.S.; Dursun, A.; Kibaek, M.; Thelle, T.; Christensen, E.; Duno, M.; Wibrand, F.
Four novel PDHA1 mutations in pyruvate dehydrogenase deficiency
J. Inherit. Metab. Dis.
32
S235-S239
2009
Homo sapiens
Guitart, M.; Andreu, A.L.; Garcia-Arumi, E.; Briones, P.; Quintana, E.; Gomez-Foix, A.M.; Garcia-Martinez, C.
FATP1 localizes to mitochondria and enhances pyruvate dehydrogenase activity in skeletal myotubes
Mitochondrion
9
266-272
2009
Homo sapiens
Uhrig, R.G.; OLeary, B.; Spang, H.E.; MacDonald, J.A.; She, Y.M.; Plaxton, W.C.
Coimmunopurification of phosphorylated bacterial- and plant-type phosphoenolpyruvate carboxylases with the plastidial pyruvate dehydrogenase complex from developing castor oil seeds
Plant Physiol.
146
1346-1357
2008
Ricinus communis
Pezzato, E.; Battaglia, V.; Brunati, A.; Agostinelli, E.; Toninello, A.
Ca2+-independent effects of spermine on pyruvate dehydrogenase complex activity in energized rat liver mitochondria incubated in the absence of exogenous Ca2+ and Mg2+
Amino Acids
36
449-456
2009
Rattus norvegicus
Contreras Ndel, P.; Vasquez, C.C.
Tellurite-induced carbonylation of the Escherichia coli pyruvate dehydrogenase multienzyme complex
Arch. Microbiol.
192
969-973
2010
Escherichia coli, Escherichia coli BW25113
Hong, W.K.; Kim, C.H.; Heo, S.Y.; Luo, L.H.; Oh, B.R.; Seo, J.W.
Enhanced production of ethanol from glycerol by engineered Hansenula polymorpha expressing pyruvate decarboxylase and aldehyde dehydrogenase genes from Zymomonas mobilis
Biotechnol. Lett.
32
1077-1082
2010
Zymomonas mobilis, Zymomonas mobilis ZM4
Zhou, Q.; Lam, P.Y.; Han, D.; Cadenas, E.
Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging
FEBS Lett.
583
1132-1140
2009
Rattus norvegicus
Patel, M.S.; Korotchkina, L.G.; Sidhu, S.
Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex
J. Mol. Catal. B
61
2-6
2009
Homo sapiens
Pei, Y.; Tarun, A.S.; Vaughan, A.M.; Herman, R.W.; Soliman, J.M.; Erickson-Wayman, A.; Kappe, S.H.
Plasmodium pyruvate dehydrogenase activity is only essential for the parasites progression from liver infection to blood infection
Mol. Microbiol.
75
957-971
2010
Plasmodium yoelii
Xing, G.; Ren, M.; Watson, W.A.; ONeill, J.T.; Verma, A.
Traumatic brain injury-induced expression and phosphorylation of pyruvate dehydrogenase: a mechanism of dysregulated glucose metabolism
Neurosci. Lett.
454
38-42
2009
Rattus norvegicus
Kannuchamy, S.; Mukund, N.; Saleena, L.M.
Genetic engineering of Clostridium thermocellum DSM1313 for enhanced ethanol production
BMC Biotechnol.
16
34
2016
Zymomonas mobilis (D9J047)
Cripps, R.E.; Eley, K.; Leak, D.J.; Rudd, B.; Taylor, M.; Todd, M.; Boakes, S.; Martin, S.; Atkinson, T.
Metabolic engineering of Geobacillus thermoglucosidasius for high yield ethanol production
Metab. Eng.
11
398-408
2009
Parageobacillus thermoglucosidasius, Parageobacillus thermoglucosidasius NCIMB 11955
Chandrasekhar, K.; Arjunan, P.; Sax, M.; Nemeria, N.; Jordan, F.; Furey, W.
Active-site changes in the pyruvate dehydrogenase multienzyme complex E1 apoenzyme component from Escherichia coli observed at 2.32 A resolution
Acta Crystallogr. Sect. D
62
1382-1386
2006
Escherichia coli (P0AFG8)
Buchholz, J.; Schwentner, A.; Brunnenkan, B.; Gabris, C.; Grimm, S.; Gerstmeir, R.; Takors, R.; Eikmanns, B.J.; Blombach, B.
Platform engineering of Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improved production of L-lysine, L-valine, and 2-ketoisovalerate
Appl. Environ. Microbiol.
79
5566-5575
2013
Corynebacterium glutamicum (Q8NNF6)
Jeng, J.; Huh, T.L.; Song, B.J.
Production of an enzymatically active E1 component of human pyruvate dehydrogenase complex in Escherichia coli supporting role of E1 beta subunit in E1 activity
Biochem. Biophys. Res. Commun.
203
225-230
1994
Homo sapiens (P08559 and P11177)
Park, Y.H.; Patel, M.S.
Characterization of interactions of dihydrolipoamide dehydrogenase with its binding protein in the human pyruvate dehydrogenase complex
Biochem. Biophys. Res. Commun.
395
416-419
2010
Homo sapiens (P09622)
Matuda, S.; Nakano, K.; Saheki, T.
Characterization and immunochemistry of pyruvate dehydrogenase complex of Ascaris muscle
Biochem. Int.
13
599-608
1986
Ascaris suum
Henderson, C.E.; Perham, R.N.
Purificaton of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus and resolution of its four component polypeptides
Biochem. J.
189
161-172
1980
Geobacillus stearothermophilus
Millar, A.; Knorpp, C.; Leaver, C.; Hill, S.
Plant mitochondrial pyruvate dehydrogenase complex Purification and identification of catalytic components in potato
Biochem. J.
334
571-576
1998
Solanum tuberosum (P52903 and P80503)
Guo, J.; Hezaveh, S.; Tatur, J.; Zeng, A.P.; Jandt, U.
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Escherichia coli
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Investigation of core structure and stability of human pyruvate dehydrogenase complex a coarse-grained approach
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Homo sapiens
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Synechocystis sp. PCC 6803 (P74490 and P73405)
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Sirtuin 3-mediated pyruvate dehydrogenase activity determines brown adipocytes phenotype under high-salt conditions
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Mus musculus (P35486)
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Thermochaetoides thermophila (G0SHF3 and G0RYE0), Thermochaetoides thermophila DSM 1495 (G0SHF3 and G0RYE0)
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Cricetulus griseus (G3H5K6)
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Homo sapiens
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Homo sapiens, Sus scrofa
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Neurospora crassa (P20285), Neurospora crassa DSM 1257 (P20285)
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Mus musculus
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