Reference on EC 1.2.1.3 - aldehyde dehydrogenase (NAD+)
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Van Ophem, P.W.; Duine, J.A.
Different types of formaldehyde-oxidizing dehydrogenases in Nocardia species 239: purification and characterization of an NAD-dependent aldehyde dehydrogenase
Arch. Biochem. Biophys.
282
248-253
1990
Nocardia sp., Nocardia sp. 239
Lindahl, R.; Evces, S.
Rat liver aldehyde dehydrogenase. II. Isolation and characterization of four inducible isozymes
J. Biol. Chem.
259
11991-11996
1984
Rattus norvegicus
Vandecasteele, J.P.; Guerrillot, L.
Aldehyde dehydrogenases from Pseudomonas aeruginosa
Methods Enzymol.
89
484-490
1982
Pseudomonas aeruginosa
Siew, C.; Deitrich, R.A.
Localization and characteristics of rat liver mitochondrial aldehyde dehydrogenases
Arch. Biochem. Biophys.
176
638-649
1976
Rattus norvegicus
Inoue, K.; Nishimukai, H.; Yamasawa, K.
Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes
Biochim. Biophys. Acta
569
117-123
1979
Homo sapiens
Coleman, M.; Vontas, J.G.; Hemingway, J.
Molecular characterization of the amplified aldehyde oxidase from insecticide resistant Culex quinquefasciatus
Eur. J. Biochem.
269
768-779
2002
Culex quinquefasciatus
Navarro-Avino, J.P.; Prasad, R.; Miralles, V.J.; Benito, R.M.; Serrano, R.
A proposal for nomenclature of aldehyde dehydrogenases in Saccharomyces cerevisiae and characterization of the stress-inducible ALD2 and ALD3 genes
Yeast
15
829-842
1999
Saccharomyces cerevisiae
Wei, B.; Ni, L.; Hurley, T.D.; Weiner, H.
Cooperativity in Nicotinamide Adenine Dinucleotide Binding Induced by Mutations of Arginine 475 Located at the Subunit Interface in the Human Liver Mitochondrial Class 2 Aldehyde Dehydrogenase
Biochemistry
39
5295-5302
2000
Homo sapiens
Fong, W.P.; Choy, K.F.
Purification and characterization of grass carp mitochondrial aldehyde dehydrogenase
Chem. Biol. Interact.
130-132
161-171
2001
Ctenopharyngodon idella
Rashkovetsky, L.G.; Maret, W.; Klyosov, A.A.
Human liver aldehyde dehydrogenases: new method of purification of the major mitochondrial and cytosolic enzymes and re-evaluation of their kinetic properties
Biochim. Biophys. Acta
1205
301-307
1994
Homo sapiens
Nosova, T.; Jokelainen, K.; Kaihovaara, P.; Heine, R.; Jousimies-Somer, H.; Salaspuro, M.
Characteristics of aldehyde dehydrogenases of certain aerobic bacteria representing human colonic flora
Alcohol Alcohol.
33
273-280
1998
Pseudomonas aeruginosa, Pseudomonas aeruginosa IH 35342
Farres, J.; Wang, X.; Takahashi, K.; Cunningham, S.J.; Wang, T.T.; Weiner, H.
Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase
J. Biol. Chem.
269
13854-13860
1994
Homo sapiens, Rattus norvegicus
Martini, R.; Murray, M.
Characterization of the in vivo inhibition of rat hepatic microsomal aldehyde dehydrogenase activity by metyrapone
Biochem. Pharmacol.
51
1187-1193
1996
Rattus norvegicus
Kikonyogo, A.; Pietruszko, R.
Aldehyde dehydrogenase from adult human brain that dehydrogenates gamma-aminobutyraldehyde: purification, characterization, cloning and distribution
Biochem. J.
316
317-324
1996
Homo sapiens
Izaguirre, G.; Kikonyogo, A.; Pietruszko, R.
Methylglyoxal as substrate and inhibitor of human aldehyde dehydrogenase: comparison of kinetic properties among the three isoenzymes
Comp. Biochem. Physiol. B
119
747-754
1998
Homo sapiens
Klyosov, A.A.
Kinetics and specificity of human liver aldehyde dehydrogenases toward aliphatic, aromatic, and fused polycyclic aldehydes
Biochemistry
35
4457-4467
1996
Homo sapiens
Rout, U.K.; Weiner, H.
Involvement of Serine 74 in the Enzyme-Coenzyme Interaction of Rat Liver Mitochondrial Aldehyde Dehydrogenase
Biochemistry
33
8955-8961
1994
Rattus norvegicus
Izaguirre, G.; Pietruszko, R.; Cho, S.; MacKerell, A.D., Jr.
Human aldehyde dehydrogenase catalytic activity and structural interactions with coenzyme analogs
J. Biomol. Struct. Dyn.
19
429-447
2001
Homo sapiens
von Bahr-Lindstroem, H.; Jeck, R.; Woenckhaus, C.; Sohn, S.; Hempel, J.; Joernvall, H.
Characterization of the coenzyme binding site of liver aldehyde dehydrogenase: differential reactivity of coenzyme analogues
Biochemistry
24
5847-5851
1985
Equus caballus
Hill, J.P.; Buckley, P.D.; Blackwell, L.F.; Motion, R.L.
Effect of pyrophosphate ions and alkaline pH on the kinetics of propionaldehyde oxidation by sheep liver cytosolic aldehyde dehydrogenase
Biochem. J.
273
691-693
1991
Ovis aries
Dickinson, F.M.
Aldehyde dehydrogenase: kinetics and mechanism
Biochem. Soc. Trans.
17
299-300
1989
Ovis aries
Poole, R.C.; Halestrap, A.P.
Purification of aldehyde dehydrogenase from rat liver mitochondria by alpha-cyanocinnamate affinity chromatography
Biochem. J.
259
105-110
1989
Rattus norvegicus
Kurys, G.; Ambroziak, W.; Pietruszko, R.
Human aldehyde dehydrogenase. Purification and characterization of a third isozyme with low Km for gamma-aminobutyraldehyde
J. Biol. Chem.
264
4715-4721
1989
Homo sapiens
Kitson, T.M.
Kinetics of p-nitrophenyl pivalate hydrolysis catalysed by cytoplasmic aldehyde dehydrogenase
Biochem. J.
257
573-578
1989
Ovis aries
Hill, J.P.; Dickinson, F.M.
Pre-steady-state kinetics of aldehyde oxidation by pig liver cytosolic aldehyde dehydrogenase
Biochem. Soc. Trans.
16
856-857
1988
Sus scrofa
-
Hill, J.P.; Dickinson, F.M.
Steady-state kinetics of aldehyde by pig liver cytosolic aldehyde dehydrogenase
Biochem. Soc. Trans.
16
857-858
1988
Ovis aries, Sus scrofa
-
Ryzlak, M.T.; Pietruszko, R.
Purification and characterization of aldehyde dehydrogenase from human brain
Arch. Biochem. Biophys.
255
409-418
1987
Homo sapiens
Ichihara, K.; Noda, Y.; Tanaka, C.; Kusunose, M.
Purification of aldehyde dehydrogenase reconstitutively active in fatty alcohol oxidation from rabbit intestinal microsomes
Biochim. Biophys. Acta
878
419-425
1986
Oryctolagus cuniculus
Bedino, S.; Testore, G.; Obert, F.
Initial characterization of aldehyde dehydrogenase from rat testis cytosol
Biol. Chem. Hoppe-Seyler
371
95-101
1990
Rattus norvegicus
Ting, H.H.; Crabbe, M.J.C.
Bovine lens aldehyde dehydrogenase. Kinetics and mechanism
Biochem. J.
215
361-368
1983
Bos taurus
Ting, H.H.; Crabbe, M.J.C.
Bovine lens aldehyde dehydrogenase. Purification and preliminary characterization
Biochem. J.
215
351-359
1983
Bos taurus
Ikawa, M.; Impraim, C.C.; Wang, G.; Yoshida, A.
Isolation and characterization of aldehyde dehydrogenase isozymes from usual and atypical human livers
J. Biol. Chem.
258
6282-6287
1983
Homo sapiens
Hart, G.J.; Dickinson, F.M.
Kinetic properties of highly purified preparations of sheep liver cytoplasmic aldehyde dehydrogenase
Biochem. J.
203
617-627
1982
Ovis aries
MacGibbon, A.K.H.; Motion, R.L.
Purification and properties of sheep-liver aldehyde dehydrogenases
Eur. J. Biochem.
96
585-595
1979
Ovis aries
Hart, G.J.; Dickinson, F.M.
Kinetic properties of aldehyde dehydrogenase from sheep liver mitochondria
Biochem. J.
175
899-908
1978
Ovis aries
Hart, G.J.; Dickinson, F.M.
Some properties of aldehyde dehydrogenase from sheep liver mitochondria
Biochem. J.
163
261-267
1977
Ovis aries
Han, I.O.; Joo, C.N.
Purification and characterization of the rat liver mitochondrial aldehyde dehydrogenase
Hanguk Saenghwahakhoe Chi
24
353-360
1991
Rattus norvegicus
-
Nakayasu, H.; Mihara, K.; Sato, R.
Purification and properties of a membrane-bound aldehyde dehydrogenase from rat liver microsomes
Biochem. Biophys. Res. Commun.
83
697-703
1978
Rattus norvegicus
Koivula, T.; Koivusalo, M.
Partial purification and properties of a phenobarbital-induced aldehyde dehydrogenase of rat liver
Biochim. Biophys. Acta
410
1-11
1975
Rattus norvegicus
Pietruszko, R.; Yonetani, T.
Aldehyde dehydrogenases from liver
Methods Enzymol.
71
772-781
1981
Equus caballus, Homo sapiens, Ovis aries
Vallari, R.C.; Pietruszko, R.
Kinetic mechanism of the human cytoplasmic aldehyde dehydrogenase E1
Arch. Biochem. Biophys.
212
9-19
1981
Homo sapiens
Greenfield, N.J.; Pietruszko, R.
Two aldehyde dehydrogenases from human liver. Isolation via affinity chromatography and characterization of the isozymes
Biochim. Biophys. Acta
483
35-45
1977
Homo sapiens
Sidhu, R.S.; Blair, A.H.
Human liver aldehyde dehydrogenase. Kinetics of aldehyde oxidation
J. Biol. Chem.
250
7899-7904
1975
Homo sapiens
Takeuchi, A.; Uritani, I.
Partial purification and characterization of aldehyde dehydrogenase from sweet potato roots
Agric. Biol. Chem.
45
1753-1759
1981
Ipomoea batatas
-
Leicht, W.; Heinz, F.; Freimueller, B.
Purification and characterization of aldehyde dehydrogenase from bovine liver
Eur. J. Biochem.
83
189-196
1978
Bos taurus
Bostian, K.A.; Betts, G.F.
Rapid purification and properties of potassium-activated aldehyde dehydrogenase from Saccharomyces cerevisiae
Biochem. J.
173
773-786
1978
Saccharomyces cerevisiae
Guerrillot, L.; Vandecasteele, J.P.
Purification and characterization of two aldehyde dehydrogenases from Pseudomonas aeruginosa
Eur. J. Biochem.
81
185-192
1977
Pseudomonas aeruginosa
Lindahl, R.; Evces, S.
Rat liver aldehyde dehydrogenase. I. Isolation and characterization of four high Km normal liver isozymes
J. Biol. Chem.
259
11986-11990
1984
Rattus norvegicus
Lee, K.H.; Kim, H.S.; Jeong, H.S.; Lee, Y.S.
Chaperonin GroESL mediates the protein folding of human liver mitochondrial aldehyde dehydrogenase in Escherichia coli
Biochem. Biophys. Res. Commun.
298
216-224
2002
Homo sapiens
Quash, G.; Fournet, G.; Chantepie, J.; Gore, J.; Ardiet, C.; Ardail, D.; Michal, Y.; Reichert, U.
Novel competitive irreversible inhibitors of aldehyde dehydrogenase (ALDH1): restoration of chemosensitivity of L1210 cells overexpressing ALDH1 and induction of apoptosis in BAF(3) cells overexpressing bcl(2)
Biochem. Pharmacol.
64
1279-1292
2002
Saccharomyces cerevisiae
Rodriguez-Zavala, J.S.; Weiner, H.
Structural aspects of aldehyde dehydrogenase that influence dimer-tetramer formation
Biochemistry
41
8229-8237
2002
Homo sapiens
Fong, W.P.; Cheng, C.H.K.; Tang, W.K.
Purification and characterization of two distinct aldehyde oxidizing enzymes from the liver of black seabream
Chem. -Biol. Interact.
143-144
159-167
2003
Acanthopagrus schlegelii
Manzer, R.; Qamar, L.; Estey, T.; Pappa, A.; Petersen, D.R.; Vasiliou, V.
Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA
DNA Cell Biol.
22
329-338
2003
Oryctolagus cuniculus, Homo sapiens
Kuznetsova, E.; Proudfoot, M.; Sanders, S.A.; Reinking, J.; Savchenko, A.; Arrowsmith, C.H.; Edwards, A.M.; Yakunin, A.F.
Enzyme genomics: Application of general enzymatic screens to discover new enzymes
FEMS Microbiol. Rev.
29
263-279
2005
Escherichia coli (P76217)
Sladek, N.E.
Human aldehyde dehydrogenases: Potential pathological, pharmacological, and toxicological impact
J. Biochem. Mol. Toxicol.
17
7-23
2003
Homo sapiens
diFabio, J.; Ji, Y.; Vasiliou, V.; Thatcher, G.R.; Bennett, B.M.
Role of mitochondrial aldehyde dehydrogenase in nitrate tolerance
Mol. Pharmacol.
64
1109-1116
2003
Rattus norvegicus
Sapag, A.; Tampier, L.; Valle-Prieto, A.; Quintanilla, M.E.; Moncada, C.; Israel, Y.
Mutations in mitochondrial aldehyde dehydrogenase (ALDH2) change cofactor affinity and segregate with voluntary alcohol consumption in rats
Pharmacogenetics
13
509-515
2003
Rattus norvegicus
Peng, X.; Shindo, K.; Kanoh, K.; Inomata, Y.; Choi, S.K.; Misawa, N.
Characterization of Sphingomonas aldehyde dehydrogenase catalyzing the conversion of various aromatic aldehydes to their carboxylic acids
Appl. Microbiol. Biotechnol.
69
141-150
2005
Sphingomonas sp. (Q402C7), Sphingomonas sp. 14DN-61 (Q402C7)
Jaureguibeitia, A.; Saa, L.; Llama, M.J.; Serra, J.L.
Purification, characterization and cloning of aldehyde dehydrogenase from Rhodococcus erythropolis UPV-1
Appl. Microbiol. Biotechnol.
73
1073-1086
2007
Rhodococcus erythropolis (Q4F895), Rhodococcus erythropolis UPV-1 (Q4F895), Rhodococcus erythropolis UPV-1
Ho, K.K.; Allali-Hassani, A.; Hurley, T.D.; Weiner, H.
Differential effects of Mg2+ ions on the individual kinetic steps of human cytosolic and mitochondrial aldehyde dehydrogenases
Biochemistry
44
8022-8029
2005
Homo sapiens (P05091), Homo sapiens
Ho, K.K.; Hurley, T.D.; Weiner, H.
Selective alteration of the rate-limiting step in cytosolic aldehyde dehydrogenase through random mutagenesis
Biochemistry
45
9445-9453
2006
Homo sapiens (P05091), Homo sapiens
Hess, D.A.; Wirthlin, L.; Craft, T.P.; Herrbrich, P.E.; Hohm, S.A.; Lahey, R.; Eades, W.C.; Creer, M.H.; Nolta, J.A.
Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells
Blood
107
2162-2169
2006
Homo sapiens
Lioznov, M.V.; Freiberger, P.; Kroeger, N.; Zander, A.R.; Fehse, B.
Aldehyde dehydrogenase activity as a marker for the quality of hematopoietic stem cell transplants
Bone Marrow Transplant.
35
909-914
2005
Homo sapiens
Doorn, J.A.; Hurley, T.D.; Petersen, D.R.
Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal
Chem. Res. Toxicol.
19
102-110
2006
Homo sapiens
Lassen, N.; Estey, T.; Tanguay, R.L.; Pappa, A.; Reimers, M.J.; Vasiliou, V.
Molecular cloning, baculovirus expression, and tissue distribution of the zebrafish aldehyde dehydrogenase 2
Drug Metab. Dispos.
33
649-656
2005
Danio rerio, Homo sapiens (P05091), Homo sapiens
Quintanilla, M.E.; Tampier, L.; Valle-Prieto, A.; Sapag, A.; Israel, Y.
Complex I regulates mutant mitochondrial aldehyde dehydrogenase activity and voluntary ethanol consumption in rats
FASEB J.
19
36-42
2005
Rattus norvegicus (P11884)
Rodriguez-Zavala, J.S.; Ortiz-Cruz, M.A.; Moreno-Sanchez, R.
Characterization of an aldehyde dehydrogenase from Euglena gracilis
J. Eukaryot. Microbiol.
53
36-42
2006
Euglena gracilis
Kim, H.J.; Joo, W.A.; Cho, C.W.; Kim, C.W.
Halophile aldehyde dehydrogenase from Halobacterium salinarum
J. Proteome Res.
5
192-195
2006
Halobacterium salinarum
Panoutsopoulos, G.I.; Beedham, C.
Metabolism of isovanillin by aldehyde oxidase, xanthine oxidase, aldehyde dehydrogenase and liver slices
Pharmacology
73
199-208
2005
Cavia porcellus
Yoon, M.; Madden, M.C.; Barton, H.A.
Developmental expression of aldehyde dehydrogenase in rat: a comparison of liver and lung development
Toxicol. Sci.
89
386-398
2006
Rattus norvegicus
McLeish, M.J.; Kneen, M.M.; Gopalakrishna, K.N.; Koo, C.W.; Babbitt, P.C.; Gerlt, J.A.; Kenyon, G.L.
Identification and characterization of a mandelamide hydrolase and an NAD(P)+dependent benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633
J. Bacteriol.
185
2451-2456
2003
Pseudomonas putida
Glatt, H.; Rost, K.; Frank, H.; Seidel, A.; Kollock, R.
Detoxification of promutagenic aldehydes derived from methylpyrenes by human aldehyde dehydrogenases ALDH2 and ALDH3A1
Arch. Biochem. Biophys.
477
196-205
2008
Homo sapiens, Homo sapiens (P05091)
Jelski, W.; Zalewski, B.; Szmitkowski, M.
The activity of class I, II, III, and IV alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) in liver cancer
Digest. Dis. Sci.
53
2550-2555
2008
Homo sapiens
Quash, G.; Fournet, G.; Courvoisier, C.; Martinez, R.M.; Chantepie, J.; Paret, M.J.; Pharaboz, J.; Joly-Pharaboz, M.O.; Gore, J.; Andre, J.; Reichert, U.
Aldehyde dehydrogenase inhibitors: alpha,beta-acetylenic N-substituted aminothiolesters are reversible growth inhibitors of normal epithelial but irreversible apoptogens for cancer epithelial cells from human prostate in culture
Eur. J. Med. Chem.
43
906-916
2008
Homo sapiens
Jelski, W.; Chrostek, L.; Szmitkowski, M.
The activity of class I, II, III, and IV of alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in pancreatic cancer
Pancreas
35
142-146
2007
Homo sapiens
Marchitti, S.A.; Deitrich, R.A.; Vasiliou, V.
Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase
Pharmacol. Rev.
59
125-150
2007
Homo sapiens, Homo sapiens (P05091), Homo sapiens (P30837), Homo sapiens (Q9H2A2)
Alnouti, Y.; Klaassen, C.D.
Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice
Toxicol. Sci.
101
51-64
2008
Mus musculus (O35945), Mus musculus (P47738), Mus musculus (P47740), Mus musculus (Q8BH00), Mus musculus (Q9CZS1)
Jo, J.E.; Mohan Raj, S.; Rathnasingh, C.; Selvakumar, E.; Jung, W.C.; Park, S.
Cloning, expression, and characterization of an aldehyde dehydrogenase from Escherichia coli K-12 that utilizes 3-hydroxypropionaldehyde as a substrate
Appl. Microbiol. Biotechnol.
81
51-60
2008
Escherichia coli
Wymore, T.; Deerfield, D.W.; Hempel, J.
Mechanistic implications of the cysteine-nicotinamide adduct in aldehyde dehydrogenase based on quantum mechanical/molecular mechanical simulations
Biochemistry
46
9495-9506
2007
Homo sapiens (P05091), Homo sapiens
Brodeur, H.; Parisotto, M.; Chagnon, S.; Mader, S.; Bhat, P.V.
Isomer-specific retinoic acid biosynthesis in HeLa cells expressing recombinant class I aldehyde dehydrogenases
Biochim. Biophys. Acta
1770
1548-1556
2007
Homo sapiens
Visus, C.; Ito, D.; Amoscato, A.; Maciejewska-Franczak, M.; Abdelsalem, A.; Dhir, R.; Shin, D.M.; Donnenberg, V.S.; Whiteside, T.L.; DeLeo, A.B.
Identification of human aldehyde dehydrogenase 1 family member A1 as a novel CD8+ T-cell-defined tumor antigen in squamous cell carcinoma of the head and neck
Cancer Res.
67
10538-10545
2007
Homo sapiens
Brichac, J.; Ho, K.K.; Honzatko, A.; Wang, R.; Lu, X.; Weiner, H.; Picklo, M.J.
Enantioselective oxidation of trans-4-hydroxy-2-nonenal is aldehyde dehydrogenase isozyme and Mg2+ dependent
Chem. Res. Toxicol.
20
887-895
2007
Rattus norvegicus (P11884), Rattus norvegicus (P51650)
Jelski, W.; Szmitkowski, M.
Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in the cancer diseases
Clin. Chim. Acta
395
1-5
2008
Homo sapiens
Gentry, T.; Foster, S.; Winstead, L.; Deibert, E.; Fiordalisi, M.; Balber, A.
Simultaneous isolation of human BM hematopoietic, endothelial and mesenchymal progenitor cells by flow sorting based on aldehyde dehydrogenase activity: implications for cell therapy
Cytotherapy
9
259-274
2007
Homo sapiens
Pearce, D.J.; Bonnet, D.
The combined use of Hoechst efflux ability and aldehyde dehydrogenase activity to identify murine and human hematopoietic stem cells
Exp. Hematol.
35
1437-1446
2007
Homo sapiens, Mus musculus
Westerlund, M.; Belin, A.C.; Felder, M.R.; Olson, L.; Galter, D.
High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract: implications for Parkinsons disease
FEBS J.
274
1212-1223
2007
Mus musculus, Rattus norvegicus
Moon, K.H.; Abdelmegeed, M.A.; Song, B.J.
Inactivation of cytosolic aldehyde dehydrogenase via S-nitrosylation in ethanol-exposed rat liver
FEBS Lett.
581
3967-3972
2007
Rattus norvegicus
Christ, O.; Lucke, K.; Imren, S.; Leung, K.; Hamilton, M.; Eaves, A.; Smith, C.; Eaves, C.
Improved purification of hematopoietic stem cells based on their elevated aldehyde dehydrogenase activity
Haematologica
92
1165-1172
2007
Homo sapiens
Hui, P.; Nakayama, T.; Morita, A.; Sato, N.; Hishiki, M.; Saito, K.; Yoshikawa, Y.; Tamura, M.; Sato, I.; Takahashi, T.; Soma, M.; Izumi, Y.; Ozawa, Y.; Cheng, Z.
Common single nucleotide polymorphisms in Japanese patients with essential hypertension: aldehyde dehydrogenase 2 gene as a risk factor independent of alcohol consumption
Hypertens. Res.
30
585-592
2007
Homo sapiens
Badawy, A.A.; Morgan, C.J.
Tryptophan metabolites as potent inhibitors of aldehyde dehydrogenase activity and potential alcoholism-aversion therapeutic agents
Int. Congr. Ser.
1304
344-351
2007
Saccharomyces cerevisiae, Rattus norvegicus
-
Hink, U.; Daiber, A.; Kayhan, N.; Trischler, J.; Kraatz, C.; Oelze, M.; Mollnau, H.; Wenzel, P.; Vahl, C.F.; Ho, K.K.; Weiner, H.; Munzel, T.
Oxidative inhibition of the mitochondrial aldehyde dehydrogenase promotes nitroglycerin tolerance in human blood vessels
J. Am. Coll. Cardiol.
50
2226-2232
2007
Homo sapiens (P05091), Homo sapiens
Povsic, T.J.; Zavodni, K.L.; Kelly, F.L.; Zhu, S.; Goldschmidt-Clermont, P.J.; Dong, C.; Peterson, E.D.
Circulating progenitor cells can be reliably identified on the basis of aldehyde dehydrogenase activity
J. Am. Coll. Cardiol.
50
2243-2248
2007
Homo sapiens
Larson, H.N.; Zhou, J.; Chen, Z.; Stamler, J.S.; Weiner, H.; Hurley, T.D.
Structural and functional consequences of coenzyme binding to the inactive Asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487
J. Biol. Chem.
282
12940-12950
2007
Homo sapiens (P05091)
Shoeb, M.; Xiao, T.L.; Hodge, R.P.; Ansari, N.H.
A specific and sensitive enzyme activity assay for aldehyde dehydrogenase 1A1 (ALDH1A1)
J. Cell Tissue Res.
8
1203-1209
2008
Bos taurus, Rattus norvegicus
-
Cahill, M.A.; Vogt, J.A.; Servos, J.; Wozny, W.; Schwall, G.P.; Groebe, K.; Schrattenholz, A.; Stegmann, W.
Metabolically stable isotope labeling prior to electrophoretic protein separation reveals differences in fractional synthesis rates between mitochondrial aldehyde dehydrogenase isoforms
J. Chromatogr. A
1161
67-70
2007
Mus musculus (P47738)
Ohsawa, I.; Nishimaki, K.; Murakami, Y.; Suzuki, Y.; Ishikawa, M.; Ohta, S.
Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity
J. Neurosci.
28
6239-6249
2008
Mus musculus (P47738), Mus musculus
Cheung, A.M.; Wan, T.S.; Leung, J.C.; Chan, L.Y.; Huang, H.; Kwong, Y.L.; Liang, R.; Leung, A.Y.
Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential
Leukemia
21
1423-1430
2007
Homo sapiens
Ma, S.; Chan, K.W.; Lee, T.K.; Tang, K.H.; Wo, J.Y.; Zheng, B.J.; Guan, X.Y.
Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations
Mol. Cancer Res.
6
1146-1153
2008
Homo sapiens
Chen, H.W.; Kuo, H.T.; Hwang, L.C.; Kuo, M.F.; Yang, R.C.
Proteomic alteration of mitochondrial aldehyde dehydrogenase 2 in sepsis regulated by heat shock response
Shock
28
710-716
2007
Rattus norvegicus
Wierzchowski, J.; Pietrzak, M.; Szelag, M.; Wroczynski, P.
Salivary aldehyde dehydrogenase-Reversible oxidation of the enzyme and its inhibition by caffeine, investigated using fluorimetric method
Arch. Oral Biol.
53
423-428
2008
Homo sapiens
Mirabelli, P.; Di Noto, R.; Lo Pardo, C.; Morabito, P.; Abate, G.; Gorrese, M.; Raia, M.; Pascariello, C.; Scalia, G.; Gemei, M.; Mariotti, E.; Del Vecchio, L.
Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies
BMC Physiol.
8
13
2008
Homo sapiens
Morimoto, K.; Kim, S.J.; Tanei, T.; Shimazu, K.; Tanji, Y.; Taguchi, T.; Tamaki, Y.; Terada, N.; Noguchi, S.
Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression
Cancer Sci.
100
1062-1068
2009
Homo sapiens
Daiber, A.; Wenzel, P.; Oelze, M.; Schuhmacher, S.; Jansen, T.; Muenzel, T.
Mitochondrial aldehyde dehydrogenase (ALDH-2)--maker of and marker for nitrate tolerance in response to nitroglycerin treatment
Chem. Biol. Interact.
178
40-47
2009
Homo sapiens
Jelski, W.; Chrostek, L.; Zalewski, B.; Szmitkowski, M.
Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with gastric cancer
Digest. Dis. Sci.
53
2101-2105
2008
Homo sapiens
Jelski, W.; Kozlowski, M.; Laudanski, J.; Niklinski, J.; Szmitkowski, M.
The activity of class I, II, III, and IV alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) in esophageal cancer
Digest. Dis. Sci.
54
725-730
2009
Homo sapiens
Jelski, W.; Orywal, K.; Panek, B.; Gacko, M.; Mroczko, B.; Szmitkowski, M.
The activity of class I, II, III and IV of alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) in the wall of abdominal aortic aneurysms
Exp. Mol. Pathol.
87
59-62
2009
Homo sapiens
Kato, T.; Miyanaga, A.; Kanaya, S.; Morikawa, M.
Gene cloning and characterization of an aldehyde dehydrogenase from long-chain alkane-degrading Geobacillus thermoleovorans B23
Extremophiles
14
33-39
2009
Geobacillus thermoleovorans, Geobacillus thermoleovorans B23
Huellner, M.W.; Schrepfer, S.; Weyand, M.; Weiner, H.; Wimplinger, I.; Eschenhagen, T.; Rau, T.
Inhibition of aldehyde dehydrogenase type 2 attenuates vasodilatory action of nitroglycerin in human veins
FASEB J.
22
2561-2568
2008
Homo sapiens
Maninang, J.; Lizada, M.; Gemma, H.
Inhibition of aldehyde dehydrogenase enzyme by Durian (Durio zibethinus Murray) fruit extract
Food Chem.
117
352-355
2009
Saccharomyces cerevisiae
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Davis, J.; Davis, D.; Norman, B.; Piatigorsky, J.
Gene expression of the mouse corneal crystallin Aldh3a1: activation by Pax6, Oct1, and p300
Invest. Ophthalmol. Vis. Sci.
49
1814-1826
2008
Mus musculus
Beretta, M.; Gruber, K.; Kollau, A.; Russwurm, M.; Koesling, D.; Goessler, W.; Keung, W.M.; Schmidt, K.; Mayer, B.
Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases
J. Biol. Chem.
283
17873-17880
2008
Homo sapiens
Giebultowicz, J.; Wolinowska, R.; Sztybor, A.; Pietrzak, M.; Wroczy?ski, P.; Wierzchowski, J.
Salivary aldehyde dehydrogenase: activity towards aromatic aldehydes and comparison with recombinant ALDH3A1
Molecules
14
2363-2372
2009
Homo sapiens
Chiang, C.P.; Wu, C.W.; Lee, S.P.; Chung, C.C.; Wang, C.W.; Lee, S.L.; Nieh, S.; Yin, S.J.
Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human pancreas: implications for pathogenesis of alcohol-induced pancreatic injury
Alcohol. Clin. Exp. Res.
33
1059-1068
2009
Homo sapiens
Lopez-Sanchez, A.; Floriano, B.; Andujar, E.; Hernaez, M.J.; Santero, E.
Tetralin-induced and ThnR-regulated aldehyde dehydrogenase and beta-oxidation genes in Sphingomonas macrogolitabida strain TFA
Appl. Environ. Microbiol.
76
110-118
2010
Sphingopyxis macrogoltabida, Sphingopyxis macrogoltabida TFA
Nakamura, T.; Ichinose, H.; Wariishi, H.
Cloning and heterologous expression of two aryl-aldehyde dehydrogenases from the white-rot basidiomycete Phanerochaete chrysosporium
Biochem. Biophys. Res. Commun.
394
470-475
2010
Phanerodontia chrysosporium, Phanerodontia chrysosporium ATCC 34541
Raj, S.; Rathnasingh, C.; Jung, W.; Selvakumar, E.; Park, S.
A novel NAD+-dependent aldehyde dehydrogenase encoded by the puuC gene of Klebsiella pneumoniae DSM 2026 that utilizes 3-hydroxypropionaldehyde as a substrate
Biotechnol. Bioprocess Eng.
15
131-138
2010
Klebsiella pneumoniae, Klebsiella pneumoniae DSM 2026
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Wei, Y.; Lin, M.; Oliver, D.
The roles of aldehyde dehydrogenases (ALDHs) in the PDH bypass of Arabidopsis
BMC Biochem.
10
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2009
Arabidopsis thaliana
Wenzl, M.V.; Woelkart, G.; Stessel, H.; Beretta, M.; Schmidt, K.; Mayer, B.
Different effects of ascorbate deprivation and classical vascular nitrate tolerance on aldehyde dehydrogenase-catalysed bioactivation of nitroglycerin
Br. J. Pharmacol.
156
1248-1255
2009
Cavia porcellus
Stagos, D.; Chen, Y.; Cantore, M.; Jester, J.V.; Vasiliou, V.
Corneal aldehyde dehydrogenases: multiple functions and novel nuclear localization
Brain Res. Bull.
81
211-218
2010
Oryctolagus cuniculus, Mus musculus (P47738), Mus musculus (Q3UNF5), Mus musculus (Q9CZS1), Mus musculus (Q9DBF1), Mus musculus
Soloveva, A.G.; Zimin, Y.V.; Razmakhov, A.M.
Kinetic parameters of liver aldehyde dehydrogenase in rats with cold injury
Bull. Exp. Biol. Med.
148
191-192
2009
Rattus norvegicus
Chen, C.H.; Sun, L.; Mochly-Rosen, D.
Mitochondrial aldehyde dehydrogenase and cardiac diseases
Cardiovasc. Res.
88
51-57
2010
Homo sapiens
Allen, E.M.; Anderson, D.G.; Florang, V.R.; Khanna, M.; Hurley, T.D.; Doorn, J.A.
Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition
Chem. Res. Toxicol.
23
1843-1850
2010
Homo sapiens
Hu, Y.; Willett, K.L.; Khan, I.A.; Scheffler, B.E.; Dasmahapatra, A.K.
Ethanol disrupts chondrification of the neurocranial cartilages in medaka embryos without affecting aldehyde dehydrogenase 1A2 (Aldh1A2) promoter methylation
Comp. Biochem. Physiol. C
150
495-502
2009
Oryzias latipes
Stagos, D.; Chen, Y.; Brocker, C.; Donald, E.; Jackson, B.C.; Orlicky, D.J.; Thompson, D.C.; Vasiliou, V.
Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme
Drug Metab. Dispos.
38
1679-1687
2010
Homo sapiens
Zhang, X.J.; Chang, L.; Zhang, Y.M.; Deng, S.; Li, Y.J.; Peng, J.
Comparing the role of glutathione-S-transferase and mitochondrial aldehyde dehydrogenase in nitroglycerin biotransformation and the correlation with calcitonin gene-related peptide
Eur. J. Pharmacol.
617
97-101
2009
Rattus norvegicus
Moon, K.H.; Lee, Y.M.; Song, B.J.
Inhibition of hepatic mitochondrial aldehyde dehydrogenase by carbon tetrachloride through JNK-mediated phosphorylation
Free Radic. Biol. Med.
48
391-398
2010
Rattus norvegicus (P11884)
Wenzl, M.V.; Beretta, M.; Gorren, A.C.; Zeller, A.; Baral, P.K.; Gruber, K.; Russwurm, M.; Koesling, D.; Schmidt, K.; Mayer, B.
Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2
J. Biol. Chem.
284
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2009
Homo sapiens (P05091)
Brocker, C.; Lassen, N.; Estey, T.; Pappa, A.; Cantore, M.; Orlova, V.V.; Chavakis, T.; Kavanagh, K.L.; Oppermann, U.; Vasiliou, V.
Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress
J. Biol. Chem.
285
18452-18463
2010
Homo sapiens, Mus musculus
Beretta, M.; Gorren, A.C.; Wenzl, M.V.; Weis, R.; Russwurm, M.; Koesling, D.; Schmidt, K.; Mayer, B.
Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1
J. Biol. Chem.
285
943-952
2010
Homo sapiens
Li, X.; Li, Y.; Wei, D.; Li, P.; Wang, L.; Feng, L.
Characterization of a broad-range aldehyde dehydrogenase involved in alkane degradation in Geobacillus thermodenitrificans NG80-2
Microbiol. Res.
165
706-712
2010
Geobacillus thermodenitrificans, Geobacillus thermodenitrificans NG80-2
Yao, L.; Fan, P.; Arolfo, M.; Jiang, Z.; Olive, M.F.; Zablocki, J.; Sun, H.L.; Chu, N.; Lee, J.; Kim, H.Y.; Leung, K.; Shryock, J.; Blackburn, B.; Diamond, I.
Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis
Nat. Med.
16
1024-1028
2010
Rattus norvegicus
Shin, J.; Kim, S.; An, G.
Rice aldehyde dehydrogenase7 is needed for seed maturation and viability
Plant Physiol.
149
905-915
2009
Oryza sativa (Q9FPK6), Oryza sativa
Kotchoni, S.O.; Jimenez-Lopez, J.C.; Gao, D.; Edwards, V.; Gachomo, E.W.; Margam, V.M.; Seufferheld, M.J.
Modeling-dependent protein characterization of the rice aldehyde dehydrogenase (ALDH) superfamily reveals distinct functional and structural features
PLoS ONE
5
e11516
2010
Oryza sativa
Kollock, R.; Rost, K.; Batke, M.; Glatt, H.
Effect of pentachlorophenol and 2,6-dichloro-4-nitrophenol on the activity of cDNA-expressed human alcohol and aldehyde dehydrogenases
Toxicol. Lett.
191
360-364
2009
Homo sapiens
Borisova, S.A.; Christman, H.D.; Metcalf, M.E.; Zulkepli, N.A.; Zhang, J.K.; van der Donk, W.A.; Metcalf, W.W.
Genetic and biochemical characterization of a pathway for the degradation of 2-aminoethylphosphonate in Sinorhizobium meliloti 1021
J. Biol. Chem.
286
22283-22290
2011
Sinorhizobium meliloti
Liu, T.; Hao, L.; Wang, R.; Liu, B.
Molecular characterization of a thermostable aldehyde dehydrogenase (ALDH) from the hyperthermophilic archaeon Sulfolobus tokodaii strain 7
Extremophiles
17
181-190
2013
Sulfurisphaera tokodaii, Sulfurisphaera tokodaii 7
Ngo, H.P.; Hong, S.H.; Oh, D.K.; Kang, L.W.
Expression, crystallization and preliminary X-ray crystallographic analysis of aldehyde dehydrogenase (ALDH) from Bacillus cereus
Acta Crystallogr. Sect. F
69
528-531
2013
Bacillus cereus, Bacillus cereus ATCC 10876
Eggert, M.W.; Byrne, M.E.; Chambers, R.P.
Kinetic involvement of acetaldehyde substrate inhibition on the rate equation of yeast aldehyde dehydrogenase
Appl. Biochem. Biotechnol.
168
824-833
2012
Saccharomyces cerevisiae
Stiti, N.; Adewale, I.O.; Petersen, J.; Bartels, D.; Kirch, H.H.
Engineering the nucleotide coenzyme specificity and sulfhydryl redox sensitivity of two stress-responsive aldehyde dehydrogenase isoenzymes of Arabidopsis thaliana
Biochem. J.
434
459-471
2011
Arabidopsis thaliana
Lee, Y.C.; Lin, D.T.; Ong, P.L.; Chen, H.L.; Lo, H.F.; Lin, L.L.
Contribution of conserved Glu255 and Cys289 residues to catalytic activity of recombinant aldehyde dehydrogenase from Bacillus licheniformis
Biochemistry
76
1233-1241
2011
Bacillus licheniformis
Mukhopadhyay, A.; Wei, B.; Weiner, H.
Mitochondrial NAD dependent aldehyde dehydrogenase either from yeast or human replaces yeast cytoplasmic NADP dependent aldehyde dehydrogenase for the aerobic growth of yeast on ethanol
Biochim. Biophys. Acta
1830
3391-3398
2013
Homo sapiens, Saccharomyces cerevisiae
Li, Y.; Su, M.; Ge, X.; Tian, P.
Enhanced aldehyde dehydrogenase activity by regenerating NAD+ in Klebsiella pneumoniae and implications for the glycerol dissimilation pathways
Biotechnol. Lett.
35
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2013
Saccharomyces cerevisiae, Klebsiella pneumoniae
Saw, Y.T.; Yang, J.; Ng, S.K.; Liu, S.; Singh, S.; Singh, M.; Welch, W.R.; Tsuda, H.; Fong, W.P.; Thompson, D.; Vasiliou, V.; Berkowitz, R.S.; Ng, S.W.
Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures
BMC Cancer
12
329
2012
Homo sapiens
Moreb, J.S.; Ucar, D.; Han, S.; Amory, J.K.; Goldstein, A.S.; Ostmark, B.; Chang, L.J.
The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance
Chem. Biol. Interact.
195
52-60
2012
Homo sapiens (P05091), Homo sapiens
Khanna, M.; Chen, C.H.; Kimble-Hill, A.; Parajuli, B.; Perez-Miller, S.; Baskaran, S.; Kim, J.; Dria, K.; Vasiliou, V.; Mochly-Rosen, D.; Hurley, T.D.
Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases
J. Biol. Chem.
286
43486-43494
2011
Homo sapiens
Yoval-Sanchez, B.; Pardo, J.P.; Rodriguez-Zavala, J.S.
New insights into the half-of-the-sites reactivity of human aldehyde dehydrogenase 1A1
Proteins
81
1330-1339
2013
Homo sapiens
Agarwal, V.; Peck, S.C.; Chen, J.H.; Borisova, S.A.; Chekan, J.R.; van der Donk, W.A.; Nair, S.K.
Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation
Chem. Biol.
21
125-135
2014
Sinorhizobium meliloti (Q92UV7)
Cao, Y.; Liao, L.; Xu, X.W.; Oren, A.; Wu, M.
Aldehyde dehydrogenase of the haloalkaliphilic archaeon Natronomonas pharaonis and its function in ethanol metabolism
Extremophiles
12
849-854
2008
Natronomonas pharaonis (A0A1U7EWW7), Natronomonas pharaonis
Lin, Y.R.; Hung, H.C.; Leu, J.H.; Wang, H.C.; Kou, G.H.; Lo, C.F.
The role of aldehyde dehydrogenase and hsp70 in suppression of white spot syndrome virus replication at high temperature
J. Virol.
85
3517-3525
2011
Penaeus vannamei
Zheng, T.; Olson, D.G.; Tian, L.; Bomble, Y.J.; Himmel, M.E.; Lo, J.; Hon, S.; Shaw, A.J.; van Dijken, J.P.; Lynd, L.R.
Cofactor specificity of the bifunctional alcohol and aldehyde dehydrogenase (AdhE) in wild-type and mutant Clostridium thermocellum and Thermoanaerobacterium saccharolyticum
J. Bacteriol.
197
2610-2619
2015
Acetivibrio thermocellus, Thermoanaerobacterium saccharolyticum, Acetivibrio thermocellus DSM 1313, Thermoanaerobacterium saccharolyticum JW/SL-YS485
Zimmerling, J.; Tischler, D.; Gromann, C.; Schlmann, M.; Oelschlgel, M.
Characterization of aldehyde dehydrogenases applying an enzyme assay with in situ formation of phenylacetaldehydes
Appl. Biochem. Biotechnol.
182
1095-1107
2017
Escherichia coli
Luo, M.; Tanner, J.J.
Structural basis of substrate recognition by aldehyde dehydrogenase 7A1
Biochemistry
54
5513-5522
2015
Homo sapiens (P49419), Homo sapiens
Stiti, N.; Podgorska, K.; Bartels, D.
Aldehyde dehydrogenase enzyme ALDH3H1 from Arabidopsis thaliana: Identification of amino acid residues critical for cofactor specificity
Biochim. Biophys. Acta
1844
681-693
2014
Arabidopsis thaliana (Q70DU8), Arabidopsis thaliana
Luo, L.H.; Seo, J.W.; Heo, S.Y.; Oh, B.R.; Kim, D.H.; Kim, C.H.
Identification and characterization of Klebsiella pneumoniae aldehyde dehydrogenases increasing production of 3-hydroxypropionic acid from glycerol
Bioprocess Biosyst. Eng.
36
1319-1326
2013
Klebsiella pneumoniae (A6T8Z5), Klebsiella pneumoniae MCG 78578 (A6T8Z5)
Sodhi, J.K.; Wong, S.; Kirkpatrick, D.S.; Liu, L.; Khojasteh, S.C.; Hop, C.E.; Barr, J.T.; Jones, J.P.; Halladay, J.S.
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
Drug Metab. Dispos.
43
908-915
2015
Homo sapiens (P05091)
Belmont-Diaz, J.A.; Yoval-Sanchez, B.; Calleja-Castaneda, L.F.; Pardo Vazquez, J.P.; Rodriguez-Zavala, J.S.
Alda-1 modulates the kinetic properties of mitochondrial aldehyde dehydrogenase (ALDH2)
FEBS J.
283
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2016
Homo sapiens
Goldstein, D.S.; Sullivan, P.; Cooney, A.; Jinsmaa, Y.; Kopin, I.J.; Sharabi, Y.
Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinsons disease
J. Neurochem.
133
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2015
Rattus norvegicus
Xu, X.; Guo, R.; Cheng, C.; Zhang, H.; Zhang, Y.; Wang, X.
Overexpression of ALDH2B8, an aldehyde dehydrogenase gene from grapevine, sustains Arabidopsis growth upon salt stress and protects plants against oxidative stress
Plant Cell
114
187-196
2013
Vitis labrusca (K9N4H5), Vitis quinquangularis (K9N4H5)
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Tuck, L.R.; Altenbach, K.; Ang, T.F.; Crawshaw, A.D.; Campopiano, D.J.; Clarke, D.J.; Marles-Wright, J.
Insight into coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans
Sci. Rep.
6
22108
2016
Lachnoclostridium phytofermentans (A9KN57)
Moretti, A.; Li, J.; Donini, S.; Sobol, R.W.; Rizzi, M.; Garavaglia, S.
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid
Sci. Rep.
6
35710
2016
Homo sapiens
van Staalduinen, L.M.; McSorley, F.R.; Schiessl, K.; Seguin, J.; Wyatt, P.B.; Hammerschmidt, F.; Zechel, D.L.; Jia, Z.
Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates
Proc. Natl. Acad. Sci. USA
111
5171-5176
2014
Sinorhizobium meliloti (Q92UV7)
Korasick, D.A.; Wyatt, J.W.; Luo, M.; Laciak, A.R.; Ruddraraju, K.; Gates, K.S.; Henzl, M.T.; Tanner, J.J.
Importance of the C-terminus of aldehyde dehydrogenase 7A1 for oligomerization and catalytic activity
Biochemistry
56
5910-5919
2017
Homo sapiens
Lim, H.G.; Noh, M.H.; Jeong, J.H.; Park, S.; Jung, G.Y.
Optimum rebalancing of the 3-hydroxypropionic acid production pathway from glycerol in Escherichia coli
ACS Synth. Biol.
5
1247-1255
2016
Azospirillum brasilense
Park, E.S.; Park, S.; Shin, J.S.
Spectrophotometric assay for sensitive detection of glycerol dehydratase activity using aldehyde dehydrogenase
J. Biosci. Bioeng.
123
528-533
2017
Klebsiella pneumoniae, Klebsiella pneumoniae DSM 2026
Sankaranarayanan, M.; Seol, E.; Kim, Y.; Chauhan, A.S.; Park, S.
Measurement of crude-cell-extract glycerol dehydratase activity in recombinant Escherichia coli using coupled-enzyme reactions
J. Ind. Microbiol. Biotechnol.
44
477-488
2017
Azospirillum brasilense
Ma, Z.; Jiang, L.; Li, G.; Liang, D.; Li, L.; Liu, L.; Jiang, C.
Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity
Bioorg. Chem.
101
103971
2020
Homo sapiens (P05091)
Lee, T.; Min, W.; Kim, H.; Seo, J.
Improved production of 3-hydroxypropionic acid in engineered Escherichia coli by rebalancing heterologous and endogenous synthetic pathways
Biores. Technol.
299
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2020
Escherichia coli
Wu, S.; Zhao, P.; Li, Q.; Tian, P.
Intensifying niacin-based biosynthesis of NAD+ to enhance 3-hydroxypropionic acid production in Klebsiella pneumoniae
Biotechnol. Lett.
43
223-234
2021
Klebsiella pneumoniae subsp. pneumoniae (A6T782), Klebsiella pneumoniae subsp. pneumoniae ATCC 700721 (A6T782)
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Li, X.; Chen, L.; Wang, X.; Tian, P.
Physiological investigations of the influences of byproduct pathways on 3-hydroxypropionic acid production in Klebsiella pneumoniae
J. Basic Microbiol.
59
1195-1207
2019
Klebsiella pneumoniae
Buchman, C.D.; Hurley, T.D.
Inhibition of the aldehyde dehydrogenase 1/2 family by psoralen and coumarin derivatives
J. Med. Chem.
60
2439-2455
2017
Homo sapiens (P05091), Homo sapiens (P30837)
Liu, L.K.; Tanner, J.J.
Crystal structure of aldehyde dehydrogenase 16 reveals trans-hierarchical structural similarity and a new dimer
J. Mol. Biol.
431
524-541
2019
Homo sapiens (Q8IZ83), Homo sapiens, Loktanella sp.
Lee, S.; Park, D.J.; Yoon, J.; Bang, S.H.; Kim, Y.H.; Min, J.
Formaldehyde treatment using overexpressed aldehyde dehydrogenase 6 from recombinant Saccharomyces cerevisiae
J. Nanosci. Nanotechnol.
18
2979-2985
2018
Saccharomyces cerevisiae (P54115), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (P54115)
Hayes, K.; Noor, M.; Djeghader, A.; Armshaw, P.; Pembroke, T.; Tofail, S.; Soulimane, T.
The quaternary structure of Thermus thermophilus aldehyde dehydrogenase is stabilized by an evolutionary distinct C-terminal arm extension
Sci. Rep.
8
13327
2018
Thermus thermophilus (Q72KD3), Thermus thermophilus, Thermus thermophilus DSM 7039 (Q72KD3), Thermus thermophilus ATCC BAA-163 (Q72KD3)
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