Information on EC 1.2.1.B23 - 4,4'-diaponeurosporen-aldehyde dehydrogenase

for references in articles please use BRENDA:EC1.2.1.B23
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The expected taxonomic range for this enzyme is: Staphylococcus aureus

EC NUMBER
COMMENTARY hide
1.2.1.B23
preliminary BRENDA-supplied EC number
RECOMMENDED NAME
GeneOntology No.
4,4'-diaponeurosporen-aldehyde dehydrogenase
-
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4,4'-diaponeurosporen-4-al + NAD(P)+ = 4,4'-diaponeurosporenoic acid + NAD(P)H + H+
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
A6QIE8
-
redox reaction
A6QIE8
-
reduction
A6QIE8
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
A6QIE8
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
A6QIE8
final enzyme in the biosynthetic pathway for staphyloxanthin, a C30 carotenoid biosynthesized by Staphylococcus aureus. Deletion of the gene abolishes staphyloxanthin biosynthesis and causes accumulation of 4,4'-diaponeurosporen-4-al. When the complete staphyloxanthin biosynthetic pathway is expressed using an artificial synthetic operon in Escherichia coli, staphyloxanthin-like compounds, which contain altered fatty acid acyl chains, and novel carotenoid compounds aere produced, indicating functional expression and coordination of the six staphyloxanthin pathway enzymes
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
4,4'-diapolycopen-4'-al-4-oic acid + NAD(P)+
4,4'-diapolycopen-4,4'-dioic acid + NAD(P)H + H+
show the reaction diagram
A6QIE8
-
-
-
?
4,4'-diapolycopen-4-al + NAD(P)+
4,4'-diapolycopenoic acid + NAD(P)H + H+
show the reaction diagram
A6QIE8
-
-
-
?
4,4'-diapolycopenedial + NAD(P)+
4,4'-diapolycopen-4'-al-4-oic acid + NAD(P)H + H+
show the reaction diagram
A6QIE8
-
-
-
?
4,4'-diaponeurosporen-4-al + NAD(P)+
4,4'-diaponeurosporenoic acid + NAD(P)H + H+
show the reaction diagram
A6QIE8
-
-
-
?