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Information on EC - enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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IUBMB Comments
One of the activities of EC, fatty-acyl-CoA synthase system, an enzyme found in yeasts (Ascomycota and Basidiomycota). Catalyses the reduction of enoyl-acyl-[acyl-carrier protein] derivatives of carbon chain length from 4 to 16. The yeast enzyme is Si-specific with respect to NADP+. cf. EC, enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) and EC, enoyl-[acyl-carrier-protein] reductase (NADPH), which describes enzymes whose stereo-specificity towards NADPH is not known. See also EC, enoyl-[acyl-carrier-protein] reductase (NADH).
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The enzyme appears in viruses and cellular organisms
enoyl reductase, enoyl-acp reductase, enoyl-acyl carrier protein reductase, etr1p, mrf1p, enoyl acyl-carrier-protein reductase, enoyl-[acyl-carrier-protein] reductase, 2-enoyl thioester reductase, 2-trans-enoyl-acp reductase, enoyl thioester reductase, more
an acyl-[acyl-carrier protein] + NADP+ = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+
show the reaction diagram
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