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Information on EC 1.3.1.110 - lactate dehydrogenase (NAD+, ferredoxin)

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IUBMB Comments
The enzyme, isolated from the bacterium Acetobacterium woodii, uses flavin-based electron confurcation to drive endergonic lactate oxidation with NAD+ as oxidant at the expense of simultaneous exergonic electron flow from reduced ferredoxin to NAD+.
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The expected taxonomic range for this enzyme is: Acetobacterium woodii
Reaction Schemes
+
2
+
2
reduced ferredoxin [iron-sulfur] cluster
=
+
2
+
2
oxidized ferredoxin [iron-sulfur] cluster
Synonyms
ldh/etf complex, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
lactate + 2 NAD+ + 2 reduced ferredoxin [iron-sulfur] cluster = pyruvate + 2 NADH + 2 oxidized ferredoxin [iron-sulfur] cluster
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