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Information on EC 1.3.1.45 - 2'-hydroxyisoflavone reductase

for references in articles please use BRENDA:EC1.3.1.45
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IUBMB Comments
In the reverse reaction, a 2'-hydroxyisoflavone is reduced to an isoflavanone; 2'-hydroxypseudobaptigenin also acts. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain.
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The enzyme appears in viruses and cellular organisms
Synonyms
CaIRL, GbIRL1, GmIFR, IFR, IRL, isoflavone reductase, isoflavone reductase-like protein, LOC100786578, More, NADPH:2'-hydroxyisoflavone oxidoreductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+
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