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Information on EC 1.3.4.1 - fumarate reductase (CoM/CoB)

for references in articles please use BRENDA:EC1.3.4.1

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IUBMB Comments

The enzyme, isolated from the archaeon Methanobacterium thermoautotrophicum, is very oxygen sensitive. It cannot use reduced flavins, reduced coenzyme F420, or NAD(P)H as an electron donor. Distinct from EC 1.3.1.6 [fumarate reductase (NADH)], EC 1.3.5.1 [succinate dehydrogenase (ubiquinone)], and EC 1.3.5.4 [fumarate reductase (quinol)].

The expected taxonomic range for this enzyme is: Bacteria, Archaea
Reaction Schemes

Synonyms
thiol:fumarate reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
fumarate + CoM + CoB = succinate + CoM-S-S-CoB
show the reaction diagram
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