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Information on EC 1.3.8.16 - 2-amino-4-deoxychorismate dehydrogenase

for references in articles please use BRENDA:EC1.3.8.16

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IUBMB Comments

The sequential action of EC 2.6.1.86, 2-amino-4-deoxychorismate synthase and this enzyme leads to the formation of the benzoxazolinate moiety of the enediyne antitumour antibiotic C-1027 [1,2].

The expected taxonomic range for this enzyme is: Streptomyces globisporus

Synonyms
ADIC dehydrogenase, EC 1.3.99.24, SgcG, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2S)-2-amino-4-deoxychorismate + FMN = 3-(1-carboxyvinyloxy)anthranilate + FMNH2
show the reaction diagram
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