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Information on EC 1.3.99.32 - glutaryl-CoA dehydrogenase (acceptor)

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IUBMB Comments
The enzyme contains FAD. The anaerobic, sulfate-reducing bacterium Desulfococcus multivorans contains two glutaryl-CoA dehydrogenases: a decarboxylating enzyme (EC 1.3.8.6), and a nondecarboxylating enzyme (this entry). The two enzymes cause different structural changes around the glutaconyl carboxylate group, primarily due to the presence of either a tyrosine or a valine residue, respectively, at the active site.
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The enzyme appears in viruses and cellular organisms
Synonyms
gdhdes, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
glutaryl-CoA + acceptor = (E)-glutaconyl-CoA + reduced acceptor
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