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Reference on EC 1.4.1.1 - alanine dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Crow, V.L.
Properties of alanine dehydrogenase and aspartase from Propionibacterium freudenreichii subsp. shermanii
Appl. Environ. Microbiol.
53
1885-1892
1987
Propionibacterium freudenreichii
Manually annotated by BRENDA team
Nitta, Y.; Yasuda, Y.; Tochikubo, K.; Hachisuka, Y.
L-Amino acid dehydrogenases in Bacillus subtilis spores
J. Bacteriol.
117
588-592
1974
Bacillus subtilis
Manually annotated by BRENDA team
Sakamoto, Y.; Nagata, S.; Esaki, N.; Tanaka, H.; Soda, K.
Gene cloning, purification and characterization of thermostable alanine dehydrogenase of bacillus stearothermophilus
J. Ferment. Bioeng.
69
154-158
1990
Geobacillus stearothermophilus
-
Manually annotated by BRENDA team
Ohshima, T.; Sakane, M.; Yamazaki, T.; Soda, K.
Thermostable alanine dehydrogenase from thermophilic Bacillus sphaericus DSM 462. Purification, characterization and kinetic mechanism
Eur. J. Biochem.
191
715-720
1990
Lysinibacillus sphaericus
Manually annotated by BRENDA team
Glasfeld, A.; Leanz, G.F.; Benner, S.A.
The stereospecificities of seven dehydrogenases from Acholeplasma laidlawii. The simplest historical model that explains dehydrogenase stereospecificity
J. Biol. Chem.
265
11692-11699
1990
Acholeplasma laidlawii
Manually annotated by BRENDA team
Honorat, A.; Monot, F.; Ballerini, D.
Synthesis of L-alanine and L-valine by enzyme systems from Bacillus megaterium
Enzyme Microb. Technol.
12
515-520
1990
Priestia megaterium
-
Manually annotated by BRENDA team
Schultz, N.A.; Benson, D.R.
Enzymes of ammonia assimilation in hyphae and vesicles of Frankia sp. strain CpI1
J. Bacteriol.
172
1380-1384
1990
Frankia sp.
Manually annotated by BRENDA team
El-Awamry, Z.A.; El-Rahmany, T.A.
Partial purification and properties of Cunninghamella elegans L-alanine dehydrogenase
Zentralbl. Mikrobiol.
144
231-240
1989
Cunninghamella elegans
Manually annotated by BRENDA team
Flores, M.E.; Sanchez, S.
Ammonium-assimilating enzymes and erythromycin formation in Saccharolypospora erythrea
J. Gen. Appl. Microbiol.
35
203-211
1989
Saccharopolyspora erythraea
-
Manually annotated by BRENDA team
Kuroda, S.; Tanizawa, K.; Sakamoto, Y.; Tanaka, H.; Soda, K.
Alanine dehydrogenases from two Bacillus species with distinct thermostabilities: molecular cloning, DNA and protein sequence determination, and structural comparison with other NAD(P)(+)-dependent dehydrogenases
Biochemistry
29
1009-1015
1990
Geobacillus stearothermophilus, Lysinibacillus sphaericus
Manually annotated by BRENDA team
Ohshima, T.; Wandrey, C.; Conrad, D.
Continous production of 3-fluoro-L-alanine dehydrogenase
Biotechnol. Bioeng.
34
394-397
1989
Lysinibacillus sphaericus
Manually annotated by BRENDA team
Caballero, F.J.; Cardenas, J.; Castillo, F.
Purification and properties of L-alanine dehydrogenase of the phototrophic bacterium Rhodobacter capsulatus E1F1
J. Bacteriol.
171
3205-3210
1989
Rhodobacter capsulatus
Manually annotated by BRENDA team
Vancurova, I.; Vancura, A.; Volc, J.; Neuzil, J.; Behal, V.
A further characterization of alanine dehydrogenase from Streptomyces aureofaciens
J. Basic Microbiol.
29
185-189
1989
Kitasatospora aureofaciens
Manually annotated by BRENDA team
Vancura, A.; Vancurova, I.; Volc, J.; Jones, S.K.T.; Flieger, M.; Basarova, G.; Behal, V.
Alanine dehydrogenase from Streptomyces fradiae. Purification and properties
Eur. J. Biochem.
179
221-227
1989
Streptomyces fradiae
Manually annotated by BRENDA team
Vancurova, I.; Vancura, A.; Volc, J.; Neuzil, J.; Flieger, M.; Basarova, G.; Behal, V.
Purification and partial characterization of alanine dehydrogenase from Streptomyces aureofaciens
Arch. Microbiol.
150
438-440
1988
Kitasatospora aureofaciens
-
Manually annotated by BRENDA team
Weiss, P.M.; Chen, C.Y.; Cleland, W.W.; Cook, P.F.
Use of primary deuterium and 15N isotope effects to deduce the relative rates of steps in the mechanisms of alanine and glutamate dehydrogenases
Biochemistry
27
4814-4822
1988
Bacillus subtilis
Manually annotated by BRENDA team
Bellion, E.; Tan, F.
An NAD+-dependent alanine dehydrogenase from a methylotrophic bacterium
Biochem. J.
244
565-570
1987
Pseudomonas sp., Pseudomonas sp. MA
Manually annotated by BRENDA team
Porumb, H.; Vancea, D.; Muresan, L.; Presecan, E.; Lascu, I.; Petrescu, I.; Porumb, T.; Pop, R.; Barzu, O.
Structural and catalytic properties of L-alanine dehydrogenase from Bacillus cereus
J. Biol. Chem.
262
4610-4615
1987
Bacillus cereus
Manually annotated by BRENDA team
Stams, A.J.M.; Hansen, T.A.
Metabolism of L-alanine in Desulfotomaculum ruminis and two marine Desulfovibrio strains
Arch. Microbiol.
145
277-279
1986
Desulforamulus ruminis, Desulfovibrio sp.
-
Manually annotated by BRENDA team
Ohshima, T.; Wandrey, C.; Sugiura, M.; Soda, K.
Screening of thermostable leucine and alanine dehydrogenases in thermophilic Bacillus strains
Biotechnol. Lett.
7
871-876
1985
Geobacillus stearothermophilus, Weizmannia coagulans, Bacillus sp. (in: Bacteria), Lysinibacillus sphaericus
-
Manually annotated by BRENDA team
Yoshida, A.; Freese, E.
Enzymic properties of Alanine dehydrogenase of Bacillus subtilis
Biochim. Biophys. Acta
96
248-262
1965
Bacillus subtilis
Manually annotated by BRENDA team
Itoh, N.; Morikawa, R.; Itoh, N.; Morikawa, R.
Crystallization and properties of L-alanine dehydrogenase from Streptomyces phaeochromogenes
Agric. Biol. Chem.
47
2511-2519
1983
Streptomyces phaeochromogenes, Bacillus subtilis, Lysinibacillus sphaericus, Streptomyces flaveus, Micromonospora melanosporea, Streptomyces bobili, Streptomyces olivochromogenes, Streptomyces roseochromogenus, Kitasatospora albolonga, Streptomyces albus, Streptomyces aureus, Streptomyces caespitosus, Streptomyces clavuligerus, Streptomyces coelicolor, Streptomyces griseoluteus, Streptomyces griseus, Streptomyces hygroscopicus, Streptomyces lydicus, Streptomyces roseus, Streptomyces ruber
-
Manually annotated by BRENDA team
Bellion, E.; Bolbot, J.A.
Nitrogen assimilation in facultative methylotrophic bacteria
Curr. Microbiol.
9
37-44
1983
Pseudomonas sp., Pseudomonas sp. MA, Pseudomonas sp. AM1
-
Manually annotated by BRENDA team
Lauwers, A.M.; Heinen, W.
Thermal properties of enzymes from Bacillus flavothermus, grown between 34 and 70C
Antonie van Leeuwenhoek
49
191-201
1983
[Bacillus] caldolyticus, Anoxybacillus flavithermus
Manually annotated by BRENDA team
Grimshaw, C.E.; Cleland, W.W.
Kinetic mechanism of Bacillus subtilis L-alanine dehydrogenase
Biochemistry
20
5650-5655
1981
Bacillus subtilis
Manually annotated by BRENDA team
Grimshaw, C.E.; Cook, P.F.; Cleland, W.W.
Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase
Biochemistry
20
5655-5661
1981
Bacillus subtilis
Manually annotated by BRENDA team
Germano, G.J.; Anderson, K.E.
Purification and properties of L-alanine dehydrogenase from Desulfovibrio desulfuricans
J. Bacteriol.
96
55-60
1968
Desulfovibrio desulfuricans
Manually annotated by BRENDA team
Alizade, M.A.; Bressler, R.; Brendel, K.
Stereochemistry of the hydrogen transfer to NAD catalyzed by (S)alanine dehydrogenase from Bacillus subtilis
Biochim. Biophys. Acta
397
5-8
1975
Bacillus subtilis
Manually annotated by BRENDA team
Sawa, Y.; Tani, M.; Murata, K.; Shibata, H.; Ochiai, H.
Purification and characterization of alanine dehydrogenase from a cyanobacterium, Phormidium lapideum
J. Biochem.
116
995-1000
1994
Bacillus subtilis, Phormidium lapideum
Manually annotated by BRENDA team
Sulzman, F.M.; Edmunds, L.N.
Characterization of circadian oscillations in alanine dehydrogenase activity in non-dividing populations of Euglena gracilis (Z)
Biochim. Biophys. Acta
320
594-609
1973
Euglena gracilis, Euglena gracilis Z
Manually annotated by BRENDA team
Muresan, L.; Vancea, D.; Presecan, E.; Porumb, H.; Lascu, I.; Oarga, M.; Matinca, D.; Abrudan, I.; Barzu, O.
Catalytic properties of Sepharose-bound L-alanine dehydrogenase from Bacillus cereus
Biochim. Biophys. Acta
742
617-622
1983
Bacillus cereus
Manually annotated by BRENDA team
Mueller, P.; Werner, D.
Alanine dehydrogenase from bacteroids and free living cells of Rhizobium japonicum
Z. Naturforsch. C
37
927-936
1982
Anabaena cylindrica, Bradyrhizobium japonicum
-
Manually annotated by BRENDA team
Tolxdorff-Neutzling, R.; Klemme, J.H.
Metabolic role and regulation of L-alanine dehydrogenase in Rhodopseudomonas capsulata
FEMS Microbiol. Lett.
13
155-159
1982
Rhodobacter capsulatus
-
Manually annotated by BRENDA team
Vali, Z.; Kilar, F.; Lakatos, S.; Venyaminov, S.A.; Zavodszky, P.
L-Alanine dehydrogenase from Thermus thermophilus
Biochim. Biophys. Acta
615
34-47
1980
Bacillus subtilis, Thermus thermophilus
Manually annotated by BRENDA team
Keradjopoulos, D.; Holldorf, A.W.
Salt-dependent conformational changes of alanine dehydrogenase from Halobacterium salinarium
FEBS Lett.
112
183-185
1980
Halobacterium salinarum
Manually annotated by BRENDA team
Aharonowitz, Y.; Friedrich, C.G.
Alanine dehydrogenase of the beta-lactam antibiotic producer Streptomyces clavuligerus
Arch. Microbiol.
125
137-142
1980
Streptomyces clavuligerus
Manually annotated by BRENDA team
Keradjopoulos, D.; Holldorf, A.W.
Purification and properties of alanine dehydrogenase from Halobacterium salinarium
Biochim. Biophys. Acta
570
1-10
1979
Halobacterium salinarum
Manually annotated by BRENDA team
Ohashima, T.; Soda, K.
Purification and properties of alanine dehydrogenase from Bacillus sphaericus
Eur. J. Biochem.
100
29-39
1979
Lysinibacillus sphaericus
Manually annotated by BRENDA team
Kim, E.K.; Fitt, P.S.
Partial purification and properties of Halobacterium cutirubrum L-alanine dehydrogenase
Biochem. J.
161
313-320
1977
Halobacterium salinarum
Manually annotated by BRENDA team
Rowell, P.; Stewart, W.D.P.
Alanine dehydrogenase of the N2-fixing blue-green alga, Anbabaena cylindrica
Arch. Microbiol.
107
115-124
1976
Anabaena cylindrica
Manually annotated by BRENDA team
Keradjopoulos, D.; Wulff, K.
Thermophilic alanine dehydrogenase from Halobacterium salinarium
Can. J. Biochem.
52
1033-1037
1974
Halobacterium salinarum
Manually annotated by BRENDA team
McCowen, S.M.; Phibbs, P.V.
Regulation of alanine dehydrogenase in Bacillus (licheniformis)
J. Bacteriol.
118
590-597
1974
Bacillus licheniformis
Manually annotated by BRENDA team
Graefe, U.; Bocker, H.; Reinhardt, G.; Tkocz, H.; Thrum, H.
Activity of alanine dehydrogenase and production of antibiotic in cultures of Streptomyces hygroscopicus JA 6599
Z. Allg. Mikrobiol.
14
181-192
1974
Streptomyces hygroscopicus
Manually annotated by BRENDA team
Borris, D.P.; Aronson, J.N.
Relationship of L-alanine and L-glutamate dehydrogenases of Bacillus thuringienses
Biochim. Biophys. Acta
191
716-718
1969
Bacillus thuringiensis
Manually annotated by BRENDA team
Keradjopoulos, D.; Holldorf, A.W.
Thermophilic character of enzymes from extreme halophilic bacteria
FEMS Microbiol. Lett.
1
179-182
1977
Bacillus cereus, Bacillus subtilis, Halobacterium salinarum, Bacillus cereus T
-
Manually annotated by BRENDA team
Laue, H.; Cook, A.M.
Purification, properties and primary structure of alanine dehydrogenase involved in taurine metabolism in the anaerobe Bilophila wadsworthia
Arch. Microbiol.
174
162-167
2000
Bilophila wadsworthia (Q9AIK2), Bilophila wadsworthia
Manually annotated by BRENDA team
Hutter, B.; Singh, M.
Host vector system for high-level expression and purification of recombinant, enzymically active alanine dehydrogenase of Mycobacterium tuberculosis
Gene
212
21-29
1998
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Allaway, D.; Lodwig, E.M.; Crompton, L.A.; Wood, M.; Parsons, R.; Wheeler, T.R.; Poole, P.S.
Identification of alanine dehydrogenase and its role in mixed secretion of ammonium and alanine by pea bacteroids
Mol. Microbiol.
36
508-515
2000
Rhizobium leguminosarum
Manually annotated by BRENDA team
Irwin, J.A.; Gudmundsson, H.M.; Marteinsson, V.T.; Hreggvidsson, G.O.; Lanzetti, A.J.; Alfredsson, G.A.; Engel, P.C.
Characterization of alanine and malate dehydrogenases from a marine psychrophile strain PA-43
Extremophiles
5
199-211
2001
Bacteria, Phormidium lapideum, Shewanella sp., Vibrio proteolyticus
Manually annotated by BRENDA team
Williamson, D.H.
L-Alanin
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
2
1724-1727
1974
Bacillus subtilis
-
Manually annotated by BRENDA team
Smith, M.T.; Emerich, D.W.
Alanine dehydrogenase from soybean nodule bacteroids: purification and properties
Arch. Biochem. Biophys.
304
379-385
1993
Rhizobium sp.
Manually annotated by BRENDA team
Delforge, D.; Devreese, B.; Dieu, M.; Delaive, E.; Van Beeumen, J.; Remacle, J.
Identification of lysine 74 in the pyruvate binding site of alanine dehydrogenase from Bacillus subtilis. Chemical modification with 2,4,6-trinitrobenzenesulfonic acid, n-succinimidyl 3-(2-pyridyldithio)propionate, and 5'-(p-(fluorosulfonyl)benzoyl)adenosine
J. Biol. Chem.
272
2276-2284
1997
Bacillus subtilis
Manually annotated by BRENDA team
Hutter, B.; Singh, M.
Properties of the 40 kDa antigen of Mycobacterium tuberculosis, a functional L-alanine dehydrogenase
Biochem. J.
343
669-672
1999
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Sedelnikova, S.; Rice, D.W.; Shibata, H.; Sawa, Y.; Baker, P.J.
Crystallization of the alanine dehydrogenase from Phormidium lapideum
Acta Crystallogr. Sect. D
54
407-408
1998
Phormidium lapideum
Manually annotated by BRENDA team
Kim, S.J.; Lee, W.Y.; Kim, K.H.
Unusual allosteric property of L-alanine dehydrogenase from Bacillus subtilis
J. Biochem. Mol. Biol.
31
25-30
1998
Bacillus subtilis
-
Manually annotated by BRENDA team
Feng, Z.; Caceres, N.E.; Sarath, G.; Barletta, R.G.
Mycobacterium smegmatis L-Alanine Dehydrogenase (Ald) Is Required for Proficient Utilization of Alanine as a Sole Nitrogen Source and Sustained Anaerobic Growth
J. Bacteriol.
184
5001-5010
2002
Mycolicibacterium smegmatis
Manually annotated by BRENDA team
Vadas, A.J.; Schroder, I.; Monbouquette, H.G.
Room-temperature synthesis of L-alanine using the alanine dehydrogenase of the hyperthermophilic archaeon archaeoglobusfulgidus
Biotechnol. Prog.
18
909-911
2002
Archaeoglobus fulgidus
Manually annotated by BRENDA team
Galkin, A.; Kulakova, L.; Ashida, H.; Sawa, Y.; Esaki, N.
Cold-adapted alanine dehydrogenases from two antarctic bacterial strains: gene cloning, protein characterization, and comparison with mesophilic and thermophilic counterparts
Appl. Environ. Microbiol.
65
4014-4020
1999
Vibrio proteolyticus, Geobacillus stearothermophilus, Bacillus subtilis, Carnobacterium sp., Shewanella sp., Carnobacterium sp. St2, Shewanella sp. Ac10
Manually annotated by BRENDA team
Usha, V.; Jayaraman, R.; Toro, J.C.; Hoffner, S.E.; Das, K.S.
Glycine and alanine dehydrogenase activities are catalyzed by the same protein in Mycobacterium smegmatis: upregulation of both activities under microaerophilic adaptation
Can. J. Microbiol.
48
7-13
2002
Mycolicibacterium smegmatis
Manually annotated by BRENDA team
Chowdhury, E.K.; Saitoh, T.; Nagata, S.; Ashiuchi, M.; Misono, H.
Alanine dehydrogenase from Enterobacter aerogenes: purification, characterization, and primary structure
Biosci. Biotechnol. Biochem.
62
2357-2363
1998
Klebsiella aerogenes
Manually annotated by BRENDA team
Hutter B; Dick T
Increased alanine dehydrogenase activity during dormancy in Mycobacterium smegmatis
FEMS Microbiol. Lett.
167
7-11
1989
Mycolicibacterium smegmatis
Manually annotated by BRENDA team
Siranosian, Kathryn Jaacks; Ireton, Keith; Grossman, Alan D.
Alanine dehydrogenase (ald) is required for normal sporulation in Bacillus subtilis
J. Bacteriol.
175
6789-6796
1993
Bacillus subtilis
Manually annotated by BRENDA team
Berberich, Robert; Kaback, Michael; Freese, Ernst.
D-Amino acids as inducers of L-alanine dehydrogenase in Bacillus subtilis
J. Biol. Chem.
243
1008-1013
1968
Bacillus subtilis
-
Manually annotated by BRENDA team
Brunhuber, N.M.W.; Blanchard, J.S.
The biochemistry and enzymology of amino acid dehydrogenases
Crit. Rev. Biochem. Mol. Biol.
29
415-467
1994
Anabaena cylindrica, Geobacillus stearothermophilus, Bacillus cereus, Bacillus subtilis, Bacillus japonicum, Bacillus licheniformis, Lysinibacillus sphaericus, Thermus thermophilus, Halobacterium salinarum, Mycobacterium tuberculosis, Pseudomonas sp., Kitasatospora aureofaciens
Manually annotated by BRENDA team
Smith, N.; Mayhew, M.; Robinson, H.; Heroux, A.; Charlton, D.; Holden, M.J.; Gallagher, D.T.
Crystallization and phasing of alanine dehydrogenase from Archaeoglobus fulgidus
Acta Crystallogr. Sect. D
59
2328-2331
2003
Archaeoglobus fulgidus
Manually annotated by BRENDA team
Irwin, J.A.; Lynch, S.V.; Coughlan, S.; Baker, P.J.; Gudmundsson, H.M.; Alfredsson, G.A.; Rice, D.W.; Engel, P.C.
Alanine dehydrogenase from the psychrophilic bacterium strain PA-43: overexpression, molecular characterization, and sequence analysis
Extremophiles
7
135-143
2003
Shewanella sp. (Q8RLH6), Shewanella sp. PA-43 (Q8RLH6)
Manually annotated by BRENDA team
Schrder, I.; Vadas, A.; Johnson, E.; Lim, S.; Monbouquette, H.G.
A novel archaeal alanine dehydrogenase homologous to ornithine cyclodeaminase and mu-crystallin
J. Bacteriol.
186
7680-7689
2004
Archaeoglobus fulgidus
Manually annotated by BRENDA team
Lodwig, E.; Kumar, S.; Allaway, D.; Bourdes, A.; Prell, J.; Priefer, U.; Poole, P.
Regulation of L-alanine dehydrogenase in Rhizobium leguminosarum bv. viciae and its role in pea nodules
J. Bacteriol.
186
842-849
2004
Rhizobium leguminosarum (Q9RLB2), Rhizobium leguminosarum (Q9RLB3)
Manually annotated by BRENDA team
Moore, B.C.; Leigh, J.A.
Markerless mutagenesis in Methanococcus maripaludis demonstrates roles for alanine dehydrogenase, alanine racemase, and alanine permease
J. Bacteriol.
187
972-979
2005
Methanococcus maripaludis
Manually annotated by BRENDA team
Bae, J.D.; Cho, Y.J.; Kim, D.I.; Lee, D.S.; Shin, H.J.
Purification and biochemical characterization of recombinant alanine dehydrogenase from Thermus caldophilus GK24
J. Microbiol. Biotechnol.
13
628-631
2003
Thermus caldophilus, Thermus caldophilus GK24
-
Manually annotated by BRENDA team
Gallagher, D.T.; Monbouquette, H.G.; Schroder, I.; Robinson, H.; Holden, M.J.; Smith, N.N.
Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and mammalian mu crystallin
J. Mol. Biol.
342
119-130
2004
Archaeoglobus fulgidus (O28608), Archaeoglobus fulgidus
Manually annotated by BRENDA team
Kato, S.i.; Ohshima, T.; Galkin, A.; Kulakova, L.; Yoshimura, T.; Esaki, N.
Purification and characterization of alanine dehydrogenase from a marine bacterium,Vibrio proteolyticus
J. Mol. Catal. B
23
373-378
2003
Vibrio proteolyticus (O85596)
-
Manually annotated by BRENDA team
Ashida, H.; Galkin, A.; Kulakova, L.; Sawa, Y.; Nakajima, N.; Esaki, N.
Conversion of cofactor specificities of alanine dehydrogenases by site-directed mutagenesis
J. Mol. Catal. B
30
173-176
2004
Shewanella sp., Phormidium lapideum (O52942), Phormidium lapideum Ac10 (O52942), Shewanella sp. Ac10
-
Manually annotated by BRENDA team
Baysal, S.H.; Yasa, I.; Uslan, A.H.
Screening and simple purification of alanine dehydrogenase in Bacillus strains
Prep. Biochem. Biotechnol.
32
277-285
2002
Priestia megaterium, Priestia megaterium LA 199
Manually annotated by BRENDA team
Forde, J.; Oakey, L.; Jennings, L.; Mulcahy, P.
Fundamental differences in bioaffinity of amino acid dehydrogenases for N6- and S6-linked immobilized cofactors using kinetic-based enzyme-capture strategies
Anal. Biochem.
338
102-112
2005
Bacillus subtilis
Manually annotated by BRENDA team
Lahmi, R.; Sendersky, E.; Perelman, A.; Hagemann, M.; Forchhammer, K.; Schwarz, R.
Alanine dehydrogenase activity is required for adequate progression of phycobilisome degradation during nitrogen starvation in Synechococcus elongatus PCC 7942
J. Bacteriol.
188
5258-5265
2006
Synechococcus elongatus
Manually annotated by BRENDA team
Scandurra, G.M.; Ryan, A.A.; Pinto, R.; Britton, W.J.; Triccas, J.A.
Contribution of L-alanine dehydrogenase to in vivo persistence and protective efficacy of the BCG vaccine
Microbiol. Immunol.
50
805-810
2006
Mycobacterium tuberculosis, no activity in Mycobacterium bovis BCG
Manually annotated by BRENDA team
Wada, M.; Narita, K.; Yokota, A.
Alanine production in an H+-ATPase- and lactate dehydrogenase-defective mutant of Escherichia coli expressing alanine dehydrogenase
Appl. Microbiol. Biotechnol.
76
819-825
2007
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Zhang, X.; Jantama, K.; Moore, J.C.; Shanmugam, K.T.; Ingram, L.O.
Production of L-alanine by metabolically engineered Escherichia coli
Appl. Microbiol. Biotechnol.
77
355-366
2007
Geobacillus stearothermophilus (A8QVZ6), Geobacillus stearothermophilus, Geobacillus stearothermophilus XL-65-6 (A8QVZ6)
Manually annotated by BRENDA team
Baysal, S.H.; Uslan, A.H.; Pala, H.H.; Tuncoku, O.
Encapsulation of PEG-urease/PEG-AlaDH within sheep erythrocytes and determination of the systems activity in lowering blood levels of urea in animal models
Artif. Cells Blood Substit. Immobil. Biotechnol.
35
391-403
2007
Bacillus subtilis
Manually annotated by BRENDA team
Agren, D.; Stehr, M.; Berthold, C.L.; Kapoor, S.; Oehlmann, W.; Singh, M.; Schneider, G.
Three-dimensional structures of apo- and holo-L-alanine dehydrogenase from Mycobacterium tuberculosis reveal conformational changes upon coenzyme binding
J. Mol. Biol.
377
1161-1173
2008
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Gorzynska, A.K.; Denger, K.; Cook, A.M.; Smits, T.H.
Inducible transcription of genes involved in taurine uptake and dissimilation by Silicibacter pomeroyi DSS-3T
Arch. Microbiol.
185
402-406
2006
Ruegeria pomeroyi (Q5LX18)
Manually annotated by BRENDA team
Ye, W.; Huo, G.; Chen, J.; Liu, F.; Yin, J.; Yang, L.; Ma, X.
Heterologous expression of the Bacillus subtilis (natto) alanine dehydrogenase in Escherichia coli and Lactococcus lactis
Microbiol. Res.
165
268-275
2009
Bacillus subtilis, Bacillus subtilis natto, no activity in Lactococcus lactis
Manually annotated by BRENDA team
Ye, W.; Huo, G.; Chen, J.; Liu, F.; Yin, J.; Yang, L.; Ma, X.
Heterologous expression of the Bacillus subtilis (natto) alanine dehydrogenase in Escherichia coli and Lactococcus lactis
Microbiol. Res.
165
268-775
2009
Bacillus subtilis (Q08352), Bacillus subtilis
Manually annotated by BRENDA team
Tripathi, S.; Ramachandran, R.
Crystal structures of the Mycobacterium tuberculosis secretory antigen alanine dehydrogenase (Rv2780) in apo and ternary complex forms captures "open" and "closed" enzyme conformations
Proteins Struct. Funct. Genet.
72
1089-1095
2008
Mycobacterium tuberculosis (P9WQB1), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQB1)
Manually annotated by BRENDA team
Nakane, K.; Suye, S.; Ueno, T.; Ohno, Y.; Ishikawa, T.; Ogihara, T.; Ogata, N.
Coimmobilization of malic enzyme and alanine dehydrogenase on organic-inorganic hybrid gel fibers and the production of L-alanine from malic acid using the fibers with coenzyme regeneration
J. Appl. Polym. Sci.
116
2901-2905
2010
Geobacillus stearothermophilus
-
Manually annotated by BRENDA team
Pernil, R.; Herrero, A.; Flores, E.
Catabolic function of compartmentalized alanine dehydrogenase in the heterocyst-forming cyanobacterium Anabaena sp. strain PCC 7120
J. Bacteriol.
192
5165-5172
2010
Anabaena sp., Anabaena sp. PCC 7120
Manually annotated by BRENDA team
Lu, X.; Yi, Q.; Zhang, G.; Zhu, X.; Zhou, H.; Dong, H.
Crystallization and preliminary X-ray analysis of an alanine dehydrogenase from Bacillus megaterium WSH-002
Acta Crystallogr. Sect. F
69
934-936
2013
Priestia megaterium (A0A0L1M9S8), Priestia megaterium WSH-002 (A0A0L1M9S8), Priestia megaterium WSH-002
Manually annotated by BRENDA team
Al-Onazi, M.; Al-Dahain, S.; El-Ansary, A.; Marraiki, N.
Isolation and characterization of Thielaviopsis paradoxa L-alanine dehydrogenase
Asian J. Appl. Sci.
4
702-711
2011
Thielaviopsis paradoxa
-
Manually annotated by BRENDA team
Giffin, M.M.; Modesti, L.; Raab, R.W.; Wayne, L.G.; Sohaskey, C.D.
ald of Mycobacterium tuberculosis encodes both the alanine dehydrogenase and the putative glycine dehydrogenase
J. Bacteriol.
194
1045-1054
2012
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Wen, J.; Li, Z.; He, G.; Xu, S.; Zhao, B.; Zhu, X.; Dong, H.; Ju, J.
Crystallization and preliminary X-ray study of alanine dehydrogenase from Bacillus pseudofirmus OF4
Acta Crystallogr. Sect. F
69
1227-1230
2013
Alkalihalophilus pseudofirmus (D3FSP2), Alkalihalophilus pseudofirmus OF4 (D3FSP2)
Manually annotated by BRENDA team
Szymanska-Majchrzak, J.; Palka, K.; Kanska, M.
Isotopic effects in mechanistic studies of biotransformations of fluorine derivatives of L-alanine catalysed by L-alanine dehydrogenase
Appl. Radiat. Isot.
123
21-25
2017
Bacillus subtilis
Manually annotated by BRENDA team
Reshma, R.S.; Saxena, S.; Bobesh, K.A.; Jeankumar, V.U.; Gunda, S.; Yogeeswari, P.; Sriram, D.
Design and development of new class of Mycobacterium tuberculosis L-alanine dehydrogenase inhibitors
Bioorg. Med. Chem.
24
4499-4508
2016
Mycobacterium tuberculosis (P9WQB1), Mycobacterium tuberculosis H37Rv (P9WQB1)
Manually annotated by BRENDA team
Lerchner, A.; Jarasch, A.; Skerra, A.
Engineering of alanine dehydrogenase from Bacillus subtilis for novel cofactor specificity
Biotechnol. Appl. Biochem.
63
616-624
2016
Bacillus subtilis
Manually annotated by BRENDA team
Saxena, S.; Samala, G.; Sridevi, J.P.; Devi, P.B.; Yogeeswari, P.; Sriram, D.
Design and development of novel Mycobacterium tuberculosis L-alanine dehydrogenase inhibitors
Eur. J. Med. Chem.
92
401-414
2015
Mycobacterium tuberculosis (P9WQB1), Mycobacterium tuberculosis H37Rv (P9WQB1)
Manually annotated by BRENDA team
Li, X.Y.; Zhang, J.C.; Zhu, Y.Y.; Su, J.G.
Domain motions and functionally-key residues of L-alanine dehydrogenase revealed by an elastic network model
Int. J. Mol. Sci.
16
29383-29397
2015
Mycobacterium tuberculosis (P9WQB1), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQB1)
Manually annotated by BRENDA team
Jeong, J.A.; Baek, E.Y.; Kim, S.W.; Choi, J.S.; Oh, J.I.
Regulation of the ald gene encoding alanine dehydrogenase by AldR in Mycobacterium smegmatis
J. Bacteriol.
195
3610-3620
2013
Mycolicibacterium smegmatis
Manually annotated by BRENDA team
Ling, B.; Bi, S.; Sun, M.; Jing, Z.; Li, X.; Zhang, R.
Molecular dynamics simulations of mutated Mycobacterium tuberculosis L-alanine dehydrogenase to illuminate the role of key residues
J. Mol. Graph. Model.
50
61-70
2014
Mycobacterium tuberculosis (P9WQB1), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQB1)
Manually annotated by BRENDA team
Giffin, M.M.; Shi, L.; Gennaro, M.L.; Sohaskey, C.D.
Role of alanine dehydrogenase of Mycobacterium tuberculosis during recovery from hypoxic nonreplicating persistence
PLoS ONE
11
e0155522
2016
Mycobacterium tuberculosis (P9WQB1), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQB1)
Manually annotated by BRENDA team
Fernandes, P.; Aldeborgh, H.; Carlucci, L.; Walsh, L.; Wasserman, J.; Zhou, E.; Lefurgy, S.; Mundorff, E.
Alteration of substrate specificity of alanine dehydrogenase
Protein Eng. Des. Sel.
28
29-35
2015
Mycobacterium tuberculosis (P9WQB1), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQB1)
Manually annotated by BRENDA team
Zech, H.; Hensler, M.; Kossmehl, S.; Drueppel, K.; Woehlbrand, L.; Trautwein, K.; Colby, T.; Schmidt, J.; Reinhardt, R.; Schmidt-Hohagen, K.; Schomburg, D.; Rabus, R.
Dynamics of amino acid utilization in Phaeobacter inhibens DSM 17395
Proteomics
13
2869-2885
2013
Phaeobacter inhibens (I7E4I1), Phaeobacter inhibens DSM 17395 (I7E4I1), Phaeobacter inhibens DSM 17395
Manually annotated by BRENDA team
Han, S.; Shin, J.
One-pot preparation of D-amino acids through biocatalytic deracemization using alanine dehydrogenase and omega-transaminase
Catal. Lett.
148
3678-3684
2018
Bacillus subtilis (Q08352), Bacillus subtilis 168 (Q08352)
-
Manually annotated by BRENDA team
Phogosee, S.; Hibino, T.; Kageyama, H.; Waditee-Sirisattha, R.
Bifunctional alanine dehydrogenase from the halotolerant cyanobacterium Aphanothece halophytica characterization and molecular properties
Arch. Microbiol.
200
719-727
2018
Aphanothece halophytica (A0A3G4YK61), Aphanothece halophytica, Aphanothece halophytica CM1 (A0A3G4YK61)
Manually annotated by BRENDA team
Ashida, H.; Sawa, Y.; Yoshimura, T.
Enzymatic determination of D-alanine with L-alanine dehydrogenase and alanine racemase
Biosci. Biotechnol. Biochem.
85
2221-2223
2021
Phormidium lapideum (O52942)
Manually annotated by BRENDA team
He, G.; Xu, S.; Wang, S.; Zhang, Q.; Liu, D.; Chen, Y.; Ju, J.; Zhao, B.
A conserved residue of L-alanine dehydrogenase from Bacillus pseudofirmus, Lys-73, participates in the catalytic reaction through hydrogen bonding
Enzyme Microb. Technol.
110
61-68
2018
Alkalihalophilus pseudofirmus (D3FSP2), Alkalihalophilus pseudofirmus OF4 (D3FSP2), Alkalihalophilus pseudofirmus ATCC BAA-2126 (D3FSP2), Alkalihalophilus pseudofirmus JCM 17055 (D3FSP2)
Manually annotated by BRENDA team
Hu, X.; Bai, Y.; Fan, T.P.; Zheng, X.; Cai, Y.
A novel type alanine dehydrogenase from Helicobacter aurati molecular characterization and application
Int. J. Biol. Macromol.
161
636-642
2020
Helicobacter aurati (A0A3D8J648), Helicobacter aurati (A0A3D8J924), Helicobacter aurati
Manually annotated by BRENDA team
Jeong, J.A.; Park, S.W.; Yoon, D.; Kim, S.; Kang, H.Y.; Oh, J.I.
Roles of alanine dehydrogenase and induction of its gene in Mycobacterium smegmatis under respiration-inhibitory conditions
J. Bacteriol.
200
e00152-18
2018
Mycolicibacterium smegmatis (A0QVQ8), Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 700084 (A0QVQ8), Mycolicibacterium smegmatis mc(2)155 (A0QVQ8)
Manually annotated by BRENDA team
Jeong, J.A.; Oh, J.I.
Alanine dehydrogenases in mycobacteria
J. Microbiol.
57
81-92
2019
no activity in Mycobacterium bovis, no activity in Mycobacterium africanum, no activity in Mycobacterium microti, Mycobacterium sp. HE5, Mycolicibacterium smegmatis (A0QVQ8), Mycolicibacterium smegmatis, Mycobacterium marinum (B2HKV6), Mycobacterium tuberculosis (P9WQB1), Mycobacterium tuberculosis, Mycobacterium marinum ATCC BAA-535 (B2HKV6), Mycolicibacterium smegmatis ATCC 700084 (A0QVQ8), Mycobacterium tuberculosis H37Rv (P9WQB1), Mycobacterium tuberculosis ATCC 25618 (P9WQB1), Mycolicibacterium smegmatis mc(2)155 (A0QVQ8)
Manually annotated by BRENDA team
Van Wieren, A.; Cook, R.; Majumdar, S.
Characterization of alanine dehydrogenase and its effect on Streptomyces coelicolorA3(2) development in liquid culture
J. Mol. Microbiol. Biotechnol.
29
57-65
2019
Streptomyces coelicolor (Q9S227), Streptomyces coelicolor, Streptomyces coelicolor A3(2) (Q9S227), Streptomyces coelicolor A3(2), Streptomyces coelicolor ATCC BAA-471 (Q9S227), Streptomyces coelicolor M145 (Q9S227)
Manually annotated by BRENDA team
da Silva, E.; Gomez-Vallejo, V.; Llop, J.; Lopez-Gallego, F.
Structural, kinetic and operational characterization of an immobilized L-aminoacid dehydrogenase
Process Biochem.
57
80-86
2017
Bacillus subtilis (Q08352), Bacillus subtilis 168 (Q08352)
-
Manually annotated by BRENDA team
Dave, U.; Kadeppagari, R.
Purification and characterization of alanine dehydrogenase from Streptomyces anulatus for its application as a bioreceptor in biosensor
Process Biochem.
68
73-82
2018
Streptomyces anulatus (A0A6G3T2F2), Streptomyces anulatus MTCC 2528 (A0A6G3T2F2)
-
Manually annotated by BRENDA team
Aktas, F.
Heterologous expression and partial characterization of a new alanine dehydrogenase from Amycolatopsis sulphurea
Protein J.
40
342-347
2021
Amycolatopsis sulphurea (A0A2A9FGJ5), Amycolatopsis sulphurea
Manually annotated by BRENDA team