show all | hide all No of entries

Information on EC 1.4.1.18 - lysine 6-dehydrogenase

for references in articles please use BRENDA:EC1.4.1.18
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
The enzyme is highly specific for L-lysine as substrate, although S-(2-aminoethyl)-L-cysteine can act as a substrate, but more slowly. While the enzyme from Agrobacterium tumefaciens can use only NAD+, that from the thermophilic bacterium Geobacillus stearothermophilus can also use NADP+, but more slowly [1,4].
Specify your search results
Select one or more organisms in this record:
Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
l-lysine 6-dehydrogenase, l-lysine epsilon-dehydrogenase, lys 6-dh, l-lysine 6-dehydrogenase (deaminating), more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-lysine + NAD+ + H2O = (S)-2-amino-6-oxohexanoate + NADH + H+ + NH3
show the reaction diagram
Select items on the left to see more content.