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Information on EC 1.6.1.4 - NAD(P)+ transhydrogenase (ferredoxin)

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IUBMB Comments
The iron-sulfur flavoprotein complex, isolated from the bacterium Clostridium kluyveri, couples the exergonic reduction of NADP+ with reduced ferredoxin and the endergonic reduction of NADP+ with NADH.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Reaction Schemes
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+
2
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2
reduced ferredoxin [iron-sulfur] cluster
=
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2
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2
oxidized ferredoxin [iron-sulfur] cluster
Synonyms
ferredoxin: NAD(P)H oxidoreductase, ferredoxin:NADP+ oxidoreductase, FprA, NADH-dependent ferredoxin NADP+ oxidoreductase I, NADH-dependent reduced ferredoxin:NADP oxidoreductase, NADH-dependent reduced ferredoxin:NADP+ oxidoreductase, NADPH:ferredoxin oxidoreductase, Nfn1, NfnAB, NfnI, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NADH + H+ + 2 NADP+ + 2 reduced ferredoxin [iron-sulfur] cluster = NAD+ + 2 NADPH + 2 oxidized ferredoxin [iron-sulfur] cluster
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