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Disease on EC 1.6.3.5 - renalase

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DISEASE
TITLE OF PUBLICATION
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Acute Kidney Injury
Human renalase: a review of its biology, function, and implications for hypertension.
Identification of a receptor for extracellular renalase.
Novel biomarkers of acute kidney injury following living donor liver transplantation.
Renalase and Biomarkers of Contrast-Induced Acute Kidney Injury.
Renalase attenuates mitochondrial fission in cisplatin-induced acute kidney injury via modulating sirtuin-3.
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Renalase, kidney and cardiovascular disease: Are they related or just coincidentally associated?
Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography.
Adenocarcinoma
Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer.
Albuminuria
A protective role of renalase in diabetic nephropathy.
Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats.
Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy.
Angina, Unstable
Association of Serum Renalase Levels and Renalase rs10887800 Polymorphism with Unstable Angina Pectoris Patients Having Metabolic Syndrome.
Aortic Coarctation
DNA synthesis in isolated arteries of normotensive and hypertensive rats: effects of the endothelium.
Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aorta.
Aortic Valve Stenosis
Functional polymorphism of the renalase gene is associated with cardiac hypertrophy in female patients with aortic stenosis.
Atherosclerosis
Association of Imaging Classification of Intracranial Cerebral Atherosclerotic Vascular Stenosis in Ischemic Stroke and Renalase Gene Polymorphisms.
Plasma Renalase is Not Associated with Blood Pressure and Brachial-Ankle Pulse Wave Velocity in Chinese Adults With Normal Renal Function.
Valsartan Promoting Atherosclerotic Plaque Stabilization by Upregulating Renalase: A Potential-Related Gene of Atherosclerosis.
Atrial Fibrillation
Renalase is associated with adverse left atrial remodelling and disease burden in patients with atrial fibrillation undergoing pulmonary vein isolation.
Breast Neoplasms
Renalase overexpression in ER-positive breast cancer.
Cardio-Renal Syndrome
Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats.
Renalase and Biomarkers of Contrast-Induced Acute Kidney Injury.
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Cardiomegaly
A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study.
Castration has antihypertensive and organoprotective effects in male but not in female heterozygous Ren-2 rats.
Catecholamines regulate the activity, secretion, and synthesis of renalase.
Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Functional polymorphism of the renalase gene is associated with cardiac hypertrophy in female patients with aortic stenosis.
Human renalase: a review of its biology, function, and implications for hypertension.
Inhibition of Angiotensin-Converting Enzyme 2 Exacerbates Cardiac Hypertrophy and Fibrosis in Ren-2 Hypertensive Rats.
Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension.
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade.
The partnership between renalase and ejection fraction as a risk factor for increased cardiac remodeling biomarkers in chronic heart failure patients.
Unchanged sarcoplasmic reticulum Ca2+-ATPase activity, reduced Ca2+ sensitivity, and negative force-frequency relationship in transgenic rats overexpressing the mouse renin gene.
Cardiovascular Diseases
Age influence on renalase and catecholamines concentration in hypertensive patients, including maintained dialysis.
Associations between renalase concentration and the occurrence of selected diseases.
Increased serum renalase in peritoneal dialysis patients: Is it related to cardiovascular disease risk?
Is renalase a novel player in catecholaminergic signaling? The mystery of the catalytic activity of an intriguing new flavoenzyme.
Relationship between renalase and N-terminal pro-B-type natriuretic peptide (NT pro-BNP) in haemodialysis patients.
Renalase - new marker or just bystander in cardiovascular disease-clinical and experimental data.
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Renalase in Children with Glomerular Kidney Diseases.
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Renalase, kidney and cardiovascular disease: Are they related or just coincidentally associated?
Roles and mechanisms of renalase in cardiovascular disease: A promising therapeutic target.
Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.
The Effect of Bilateral Nephrectomy on Renalase and Catecholamines in Hemodialysis Patients.
Coronary Artery Disease
A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study.
Age influence on renalase and catecholamines concentration in hypertensive patients, including maintained dialysis.
Atorvastatin and losartan may upregulate renalase activity in hypertension but not coronary artery diseases: The role of gene polymorphism.
Circulating renalase, catecholamines, and vascular adhesion protein 1 in hypertensive patients.
Correlation between plasma renalase level and coronary artery disease.
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
Rs10887800 renalase gene polymorphism is associated with an increased risk of coronary artery disease in hemodialyzed patients.
Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease ? a cross-sectional study.
Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography.
Coronary Disease
Renalase gene polymorphism in patients with hypertension and concomitant coronary heart disease.
Coronary Stenosis
Correlation between plasma renalase level and coronary artery disease.
COVID-19
Decreased plasma levels of the survival factor renalase are associated with worse outcomes in COVID-19.
Cysts
Renalase: Another puzzle piece between hypertension and simple renal cysts?
Diabetes Mellitus
Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease.
Renal redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic nephropathy: paying homage to the podocyte.
Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus.
Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes.
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Diabetes Mellitus, Type 1
Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes.
Renalase: its role as a cytokine, and an update on its association with type 1 diabetes and ischemic stroke.
Diabetes Mellitus, Type 2
Polymorphism of the renalase gene in gestational diabetes mellitus.
Renal redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic nephropathy: paying homage to the podocyte.
Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus.
Renalase gene polymorphisms in patients with type 2 diabetes, hypertension and stroke.
Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes.
Diabetes, Gestational
Polymorphism of the renalase gene in gestational diabetes mellitus.
Diabetic Cardiomyopathies
FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy.
FT23, an orally active antifibrotic compound, attenuates structural and functional abnormalities in an experimental model of diabetic cardiomyopathy.
Functional, structural and molecular aspects of diastolic heart failure in the diabetic (mRen-2)27 rat.
Diabetic Nephropathies
A protective role of renalase in diabetic nephropathy.
Effects of low-dose and early versus late perindopril treatment on the progression of severe diabetic nephropathy in (mREN-2)27 rats.
Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenic Ren-2 rats.
Progressive diabetic nephropathy in the Ren-2 rat.
Renal injury in streptozotocin-diabetic Ren2-transgenic rats is mainly dependent on hypertension, not on diabetes.
Diabetic Retinopathy
Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus.
Valsartan but not atenolol improves vascular pathology in diabetic Ren-2 rat retina.
Essential Hypertension
A genetic model of malignant phase hypertension in rats.
Identification of a receptor for extracellular renalase.
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Regulation of blood pressure and cardiovascular function by renalase.
Renalase gene is a novel susceptibility gene for essential hypertension: a two-stage association study in northern Han Chinese population.
Renalase, a new renal hormone: its role in health and disease.
Transcriptional regulation of the novel monoamine oxidase renalase: Crucial roles of transcription factors Sp1, STAT3, and ZBP89.
Fatty Liver
Renalase Attenuates Mouse Fatty Liver Ischemia/Reperfusion Injury through Mitigating Oxidative Stress and Mitochondrial Damage via Activating SIRT1.
Fibroadenoma
Renalase overexpression in ER-positive breast cancer.
Gastrointestinal Diseases
Renalase: A Multi-Functional Signaling Molecule with Roles in Gastrointestinal Disease.
Glomerulonephritis, IGA
Renalase in Children with Glomerular Kidney Diseases.
[OP.6A.01] RENALASE IN CHILDREN WITH GLOMERULAR KIDNEY DISEASES.
Heart Diseases
An association study on renalase polymorphisms and ischemic stroke in a Chinese population.
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Roles and mechanisms of renalase in cardiovascular disease: A promising therapeutic target.
Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta.
Heart Failure
Association of Plasma Renalase and Left Ventricle Mass Index in Heart Failure Patients Stratified to the Category of the Ejection Fraction: A Pilot Study.
Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat.
Effect of angiotensin-converting enzyme blockade, alone or combined with blockade of soluble epoxide hydrolase, on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula.
Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation.
Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats.
Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula.
Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats.
Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula.
Renalase deficiency in heart failure model of rats--a potential mechanism underlying circulating norepinephrine accumulation.
Renalase improves pressure overload-induced heart failure in rats by regulating extracellular signal-regulated protein kinase 1/2 signaling.
Sex-linked differences in the course of chronic kidney disease and congestive heart failure: a study in 5/6 nephrectomized Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula.
Sex-linked differences in the mortality in Ren-2 transgenic hypertensive rats with aorto-caval fistula: effects of treatment with angiotensin converting enzyme alone and combined with inhibitor of soluble epoxide hydrolase.
The Discriminatory Ability of Renalase and Biomarkers of Cardiac Remodeling for the Prediction of Ischemia in Chronic Heart Failure Patients With the Regard to the Ejection Fraction.
The partnership between renalase and ejection fraction as a risk factor for increased cardiac remodeling biomarkers in chronic heart failure patients.
Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure.
Hypertension
A novel marker in pregnant with preeclampsia: renalase.
Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse ren-2 gene.
Activation and function of prorenin: different viewpoints.
Alterations in coronary artery vascular reactivity of hypertensive Ren-2 transgenic rats.
Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure.
An association study on renalase polymorphisms and ischemic stroke in a Chinese population.
Angiotensin and bradykinin peptides in the TGR(mRen-2)27 rat.
Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions.
Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.
Association of Imaging Classification of Intracranial Cerebral Atherosclerotic Vascular Stenosis in Ischemic Stroke and Renalase Gene Polymorphisms.
Association of Renalase SNPs rs2296545 and rs2576178 with the Risk of Hypertension: A Meta-Analysis.
AT1 receptor antisense therapy transiently lowers blood pressure in Ren-2 transgenic rats.
Atorvastatin and losartan may upregulate renalase activity in hypertension but not coronary artery diseases: The role of gene polymorphism.
Basal and Activated Calcium Sensitization Mediated by RhoA/Rho Kinase Pathway in Rats with Genetic and Salt Hypertension.
Blockade of endothelin receptors attenuates end-organ damage in homozygous hypertensive ren-2 transgenic rats.
Cardiorenal protective effects of vasopeptidase inhibition with omapatrilat in hypertensive transgenic (mREN-2)27 rats.
Cardiovascular end-organ damage in Ren-2 transgenic rats compared to spontaneously hypertensive rats.
Catecholamines regulate the activity, secretion, and synthesis of renalase.
Changes of blood pressure and aortic strip contractile responses to ET-1 of heterozygous female transgenic rats, TGR(mRen2)27.
Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27.
Chronic endothelin receptor blockade reduces end-organ damage independently of blood pressure effects in salt-loaded heterozygous Ren-2 transgenic rats.
Circadian rhythms in renal function in hypertensive TGR(mRen-2)27 rats and their normotensive controls.
Circulating renalase, catecholamines, and vascular adhesion protein 1 in hypertensive patients.
Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.
Combined suppression of the intrarenal and circulating vasoconstrictor renin-ACE-ANG II axis and augmentation of the vasodilator ACE2-ANG 1-7-Mas axis attenuates the systemic hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat.
Differential gene expression of renin and angiotensinogen in the TGR(mREN-2)27 transgenic rat.
Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats.
Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats.
Effects of anesthesia on plasma and kidney ANG II levels in normotensive and ANG II-dependent hypertensive rats.
Effects of angiotensin-converting enzyme inhibitor and angiotensin type 1 receptor antagonist in deoxycorticosterone acetate-salt hypertensive mice lacking Ren-2 gene.
Effects of changes in sodium balance on plasma and kidney angiotensin II levels in anesthetized and conscious Ren-2 transgenic rats.
Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats.
Effects of combined endothelin a receptor and renin-angiotensin system blockade on the course of end-organ damage in 5/6 nephrectomized Ren-2 hypertensive rats.
Effects of dietary salt load and salt depletion on the course of hypertension and angiotensin II levels in male and female heterozygous Ren-2 transgenic rats.
Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation.
Effects of salt intake and potassium supplementation on renalase expression in the kidneys of Dahl salt-sensitive rats.
Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Enalapril and pressure-diuresis in hypertensive rats transgenic for mouse renin gene.
End-organ damage in hypertensive transgenic Ren-2 rats: influence of early and late endothelin receptor blockade.
Endothelial dysfunction in the aorta of transgenic rats harboring the mouse Ren-2 gene.
Endothelial injury in transgenic (mRen-2)27 hypertensive rats.
Endothelial vasoconstrictor prostanoids modulate contractions to acetylcholine and ANG II in Ren-2 rats.
Endothelin receptor blockade does not affect blood pressure or angiotensin II levels in CYP1A1-Ren-2 transgenic rats with acutely induced hypertension.
Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats.
Estrogen augments the contribution of nitric oxide to blood pressure regulation in transgenic hypertensive rats expressing the mouse Ren-2 gene.
Exercise training prevents development of cardiac contractile dysfunction in hypertensive TG (mREN-2)27 rats.
FT011, a Novel Cardiorenal Protective Drug, Reduces Inflammation, Gliosis and Vascular Injury in Rats with Diabetic Retinopathy.
Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene.
Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models.
High-performance Liquid Chromatography Measured Metabolites of Endogenous Catecholamines and Their Relations to Chronic Kidney Disease and High Blood Pressure in Heart Transplant Recipients.
Human renalase: a review of its biology, function, and implications for hypertension.
Hypertension and kidney disease: is renalase a new player or an innocent bystander?
Hypertension in dialysis.
Hypertension in the (mRen-2)27 rat is not explained by enhanced kinetics of transgenic Ren-2 renin.
Hypertension in the transgenic rat TGR(mRen-2)27 may be due to enhanced kinetics of the reaction between mouse renin and rat angiotensinogen.
Impact of renal denervation on renalase expression in adult rats with spontaneous hypertension.
Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats.
Increased vascular angiotensin formation in female rats harboring the mouse Ren-2 gene.
Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula.
Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats.
Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension.
Local hormonal factors (intracrine, autocrine, and paracrine) in hypertension.
Long-term prevention of hypertension and end-organ damage in Ren-2 transgenic rats is achieved only with persistent but not transient AT1 receptor blockade.
Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aorta.
Mechanisms of hypertension in transgenic rats expressing the mouse Ren-2 gene.
Morphology and function of the adrenal zona glomerulosa of transgenic rats TGR [mREN2] 27: effects of prolonged sodium restriction.
Myocardial remodeling in hypertensive Ren-2 transgenic rats.
Nifedipine-sensitive blood pressure component in hypertensive models characterized by high activity of either sympathetic nervous system or renin-angiotensin system.
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Omega-3 polyunsaturated fatty acid supplementation reduces hypertension in TGR(mRen-2)27 rats.
Ontogenetic regulation of mouse Ren-2d renin gene in transgenic hypertensive rats, TGR(mREN2)27.
Plasma renalase concentration before and after radiofrequency renal denervation in patients with resistant hypertension.
Plasma Renalase is Not Associated with Blood Pressure and Brachial-Ankle Pulse Wave Velocity in Chinese Adults With Normal Renal Function.
Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension.
Recent insights on circulating catecholamines in hypertension.
Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade.
Reduction of oxidative stress does not attenuate the development of angiotensin II-dependent hypertension in Ren-2 transgenic rats.
Regulation of blood pressure and cardiovascular function by renalase.
Regulation of renalase expression by D5 dopamine receptors in rat renal proximal tubule cells.
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Renal function in hypertensive rats transgenic for mouse renin gene.
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula.
Renalase - new marker or just bystander in cardiovascular disease-clinical and experimental data.
Renalase and hypertension-demographic and clinical correlates in obstructive sleep apnea.
Renalase Assessment With Regard to Kidney Function, Lipid Disturbances, and Endothelial Dysfunction Parameters in Stable Renal Transplant Recipients.
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Renalase deficiency aggravates ischemic myocardial damage.
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Renalase gene polymorphism and epinephrine level in chronic kidney disease.
Renalase gene polymorphism in patients with hypertension and concomitant coronary heart disease.
Renalase gene polymorphisms in patients with type 2 diabetes, hypertension and stroke.
Renalase Gene rs2576178 Polymorphism in Hemodialysis Patients: Study in Bosnia and Herzegovina.
Renalase improves pressure overload-induced heart failure in rats by regulating extracellular signal-regulated protein kinase 1/2 signaling.
Renalase in Haemodialysis Patients with Chronic Kidney Disease.
Renalase in hypertension and kidney disease.
Renalase is Removed by Kidneys and During Dialysis - Excess Related to CKD Complications?
Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes.
Renalase mRNA levels in the brain, heart, and kidneys of spontaneously hypertensive rats with moderate and high hypertension.
Renalase rs10887800 polymorphism is associated with severe pre-eclampsia in southeast Iranian women.
Renalase, a new renal hormone: its role in health and disease.
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Renalase, a Novel Enzyme Involved in Blood Pressure Regulation, Is Related to Kidney Function but Not to Blood Pressure in Hemodialysis Patients.
Renalase, Catecholamine and Nitric Oxide Changes Before and After Sodium Nitroprusside Administration to Patients who Develop Post-Coronary Artery By-Pass (CABG) Hypertension.
Renalase, Hypertension, and Kidney -- The Discussion Continues.
Renalase, kidney and cardiovascular disease: Are they related or just coincidentally associated?
Renalase, stroke, and hypertension in hemodialyzed patients.
Renalase: Another puzzle piece between hypertension and simple renal cysts?
Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
Role of renalase in the regulation of blood pressure and the renal dopamine system.
Roles of AT1 and AT2 receptors in the hypertensive Ren-2 gene transgenic rat kidney.
Roles of nitric oxide and oxidative stress in the regulation of blood pressure and renal function in prehypertensive Ren-2 transgenic rats.
Serum Renalase Levels in Adolescents with Primary Hypertension.
Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.
Sex-linked differences in the course of chronic kidney disease and congestive heart failure: a study in 5/6 nephrectomized Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula.
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independents effects?
Sodium-dependent modulation of systemic and urinary renalase expression and activity in the rat remnant kidney.
Spontaneous development of malignant phase hypertension in transgenic Ren-2 rats.
Studies on blood pressure regulation in hypertensive ren-2 transgenic rats.
Synthesis of human renalase1 in Escherichia coli and its purification as a FAD-containing holoprotein.
The absence of sympathoexcitation during the development of hypertension in Cyp1a1 Ren-2 transgenic rats.
The association study on renalase polymorphism and hypertension: a meta-analysis.
The Effect of Bilateral Nephrectomy on Renalase and Catecholamines in Hemodialysis Patients.
The effects of repeated delivery of angiotensin II AT(1) receptor antisense on distinct vasoactive systems in Ren-2 transgenic rats: young vs. adult animals.
The hypertensive Ren-2 transgenic rat TGR (mREN2)27 in hypertension research. Characteristics and functional aspects.
The Relationship between Sleep Bruxism Intensity and Renalase Concentration-An Enzyme Involved in Hypertension Development.
The Renalase Asp37Glu polymorphism is not associated with hypertension and cardiovascular events in an urban-based prospective cohort: the Malmö Diet and cancer study.
The renin-angiotensin system in transgenic rats.
The role of intrarenal angiotensin II in the development of hypertension in Ren-2 transgenic rats.
The role of urinary renalase on early-stage renal damage in Chinese adults with primary hypertension.
Therapeutic perspectives in hypertension: novel means for renin-angiotensin-aldosterone system modulation and emerging device-based approaches.
Transgenic rats carrying the mouse renin gene--morphological characterization of a low-renin hypertension model.
Transgenic rats: tools to study the function of the renin-angiotensin system.
Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.
Zona glomerulosa of the adrenal gland in a transgenic strain of rat: a morphologic and functional study.
Zonal distribution and regulation of adrenal renin in a transgenic model of hypertension in the rat.
[Morphological characteristic of renal injury in hypertensive rat strain transgenic for the mouse Ren-2 renin gene (TGR [mRen2] 27]
[OP.6A.01] RENALASE IN CHILDREN WITH GLOMERULAR KIDNEY DISEASES.
[Renalase and its role in the development of hypertension in patients with chronic renal failure].
Hypertension, Malignant
Endothelin receptor blockade does not affect blood pressure or angiotensin II levels in CYP1A1-Ren-2 transgenic rats with acutely induced hypertension.
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Hypertension, Pulmonary
Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Hypertrophy, Left Ventricular
Functional polymorphism of the renalase gene is associated with cardiac hypertrophy in female patients with aortic stenosis.
Hypophosphatemia
Renalase regulates renal dopamine and phosphate metabolism.
Hypophosphatemia, Familial
Renalase, Hypertension, and Kidney -- The Discussion Continues.
Hypotension
Online Haemodiafiltration Improves Inflammatory State in Dialysis Patients: A Longitudinal Study.
Infertility
Single nucleotide polymorphisms in Renalase and KCNQ1 genes and female infertility: A cross-sectional study in Pakistan.
Infertility, Female
Associations between renalase concentration and the occurrence of selected diseases.
Single nucleotide polymorphisms in Renalase and KCNQ1 genes and female infertility: A cross-sectional study in Pakistan.
Insulin Resistance
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression.
Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes.
Ischemic Stroke
An association study on renalase polymorphisms and ischemic stroke in a Chinese population.
Association of Imaging Classification of Intracranial Cerebral Atherosclerotic Vascular Stenosis in Ischemic Stroke and Renalase Gene Polymorphisms.
Associations between renalase concentration and the occurrence of selected diseases.
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Renalase: its role as a cytokine, and an update on its association with type 1 diabetes and ischemic stroke.
Kidney Diseases
A new method for quantitative determination of renalase based on mass spectrometric determination of a proteotypic peptide labelled with stable isotopes.
Associations between renalase concentration and the occurrence of selected diseases.
Hypertension and kidney disease: is renalase a new player or an innocent bystander?
Is renalase a novel player in catecholaminergic signaling? The mystery of the catalytic activity of an intriguing new flavoenzyme.
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Renalase in Children with Glomerular Kidney Diseases.
Renalase in hypertension and kidney disease.
Renalase, a Novel Enzyme Involved in Blood Pressure Regulation, Is Related to Kidney Function but Not to Blood Pressure in Hemodialysis Patients.
[OP.6A.01] RENALASE IN CHILDREN WITH GLOMERULAR KIDNEY DISEASES.
Kidney Failure, Chronic
Human renalase: a review of its biology, function, and implications for hypertension.
Hypertension in dialysis.
Identification, expression and tissue distribution of a renalase homologue from mouse.
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients.
Plasma renalase in chronic kidney disease: differences and similarities between humans and rats.
Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension.
Regulation of blood pressure and cardiovascular function by renalase.
Relationship between renalase and N-terminal pro-B-type natriuretic peptide (NT pro-BNP) in haemodialysis patients.
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Renalase gene polymorphism and epinephrine level in chronic kidney disease.
Renalase is a novel renal hormone that regulates cardiovascular function.
Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure.
Renalase Secreted by Human Kidney HEK293T Cells Lacks its N-Terminal Peptide: Implications for Putative Mechanisms of Renalase Action.
Rs10887800 renalase gene polymorphism is associated with an increased risk of coronary artery disease in hemodialyzed patients.
Liver Cirrhosis
Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model.
Lupus Nephritis
Serum Renalase Levels Correlate with Disease Activity in Lupus Nephritis.
Melanoma
Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism.
Metabolic Diseases
Post-Transcriptional Regulation of Renalase Gene by miR-29 and miR-146 MicroRNAs: Implications for Cardiometabolic Disorders.
Metabolic Syndrome
Association of Serum Renalase Levels and Renalase rs10887800 Polymorphism with Unstable Angina Pectoris Patients Having Metabolic Syndrome.
Muscular Atrophy
Denervation-induced muscle atrophy suppression in renalase-deficient mice via increased protein synthesis.
Myocardial Infarction
Serum Renalase Levels Are Predicted by Brain-Derived Neurotrophic Factor and Associated with Cardiovascular Events and Mortality after Percutaneous Coronary Intervention.
Myocardial Ischemia
Renalase protects the cardiomyocytes of Sprague-Dawley rats against ischemia and reperfusion injury by reducing myocardial cell necrosis and apoptosis.
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Neoplasms
Elevated renalase levels in patients with acute coronary microvascular dysfunction - A possible biomarker for ischemia.
Expression of murine renin genes in subcutaneous connective tissue.
Extracellular renalase protects cells and organs by outside-in signalling.
Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer.
Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism.
Renalase overexpression in ER-positive breast cancer.
The Renalase Asp37Glu polymorphism is not associated with hypertension and cardiovascular events in an urban-based prospective cohort: the Malmö Diet and cancer study.
Nephritis
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Nephrosclerosis
Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats.
Nephrotic Syndrome
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Renalase in Children with Glomerular Kidney Diseases.
[OP.6A.01] RENALASE IN CHILDREN WITH GLOMERULAR KIDNEY DISEASES.
Non-alcoholic Fatty Liver Disease
Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model.
Obesity
Elevated renalase levels in patients with acute coronary microvascular dysfunction - A possible biomarker for ischemia.
Normal values for urine renalase excretion in children.
Pancreatic Neoplasms
Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer.
Pancreatitis
The serum protein renalase reduces injury in experimental pancreatitis.
Paraganglioma
Can cerebellin and renalase measurements contribute to the elimination of false positive results in pheochromocytoma and paraganglioma diagnoses?
Pheochromocytoma
Can cerebellin and renalase measurements contribute to the elimination of false positive results in pheochromocytoma and paraganglioma diagnoses?
Polycystic Ovary Syndrome
Single nucleotide polymorphisms in Renalase and KCNQ1 genes and female infertility: A cross-sectional study in Pakistan.
Pre-Eclampsia
A novel marker in pregnant with preeclampsia: renalase.
Renalase gene polymorphism is associated with increased blood pressure in preeclampsia.
Renalase rs10887800 polymorphism is associated with severe pre-eclampsia in southeast Iranian women.
Serum anti mullerian hormone and renalase levels in predicting the risk of preeclampsia.
Proteinuria
Castration has antihypertensive and organoprotective effects in male but not in female heterozygous Ren-2 rats.
Effects of Renin-Angiotensin System Inhibitors on Renal Expression of Renalase in Sprague-Dawley Rats Fed With High Salt Diet.
Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension.
Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats.
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Renalase in Children with Glomerular Kidney Diseases.
Renoprotective effects of ET(A) receptor antagonists therapy in experimental non-diabetic chronic kidney disease: Is there still hope for the future?
Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes.
Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.
[OP.6A.01] RENALASE IN CHILDREN WITH GLOMERULAR KIDNEY DISEASES.
Renal Insufficiency
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Renal Insufficiency, Chronic
Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats.
Cardioprotective Effect of Renalase in 5/6 Nephrectomized Rats.
Catecholamines regulate the activity, secretion, and synthesis of renalase.
Chronic kidney disease is associated with increased levels of renalase in serum and decreased in erythrocytes.
Circulating Levels of Renalase, Norepinephrine, and Dopamine in Dialysis Patients.
Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease.
Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease.
High-performance Liquid Chromatography Measured Metabolites of Endogenous Catecholamines and Their Relations to Chronic Kidney Disease and High Blood Pressure in Heart Transplant Recipients.
Human renalase: a review of its biology, function, and implications for hypertension.
Increased serum renalase in peritoneal dialysis patients: Is it related to cardiovascular disease risk?
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Plasma renalase in chronic kidney disease: differences and similarities between humans and rats.
Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension.
Regulation of blood pressure and cardiovascular function by renalase.
Relationship between renalase and N-terminal pro-B-type natriuretic peptide (NT pro-BNP) in haemodialysis patients.
Renalase - new marker or just bystander in cardiovascular disease-clinical and experimental data.
Renalase Assessment With Regard to Kidney Function, Lipid Disturbances, and Endothelial Dysfunction Parameters in Stable Renal Transplant Recipients.
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Renalase gene polymorphism and epinephrine level in chronic kidney disease.
Renalase in children with chronic kidney disease.
Renalase in chronic kidney disease: the evolving story.
Renalase in chronic kidney disease: the evolving story. Authors' reply.
Renalase in Haemodialysis Patients with Chronic Kidney Disease.
Renalase is a novel renal hormone that regulates cardiovascular function.
Renalase, a new renal hormone: its role in health and disease.
Renalase-specific polyclonal antibody and its application in the detection of renalase's expression.
Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ETA Blockade.
Role of renalase in the regulation of blood pressure and the renal dopamine system.
Serum renalase is related to catecholamine levels and renal function.
Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.
Sex-linked differences in the course of chronic kidney disease and congestive heart failure: a study in 5/6 nephrectomized Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula.
Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease ? a cross-sectional study.
[Renalase and its role in the development of hypertension in patients with chronic renal failure].
renalase deficiency
Denervation-induced muscle atrophy suppression in renalase-deficient mice via increased protein synthesis.
Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model.
Human renalase: a review of its biology, function, and implications for hypertension.
Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aorta.
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Plasma renalase in chronic kidney disease: differences and similarities between humans and rats.
Renalase deficiency aggravates ischemic myocardial damage.
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Renalase deficiency in heart failure model of rats--a potential mechanism underlying circulating norepinephrine accumulation.
Renalase gene polymorphism and epinephrine level in chronic kidney disease.
Renalase is Removed by Kidneys and During Dialysis - Excess Related to CKD Complications?
Renalase regulates peripheral and central dopaminergic activities.
Renalase regulates renal dopamine and phosphate metabolism.
Renalase, a new renal hormone: its role in health and disease.
Role of renalase in the regulation of blood pressure and the renal dopamine system.
[Renalase and its role in the development of hypertension in patients with chronic renal failure].
Reperfusion Injury
Renalase as a Novel Biomarker for Evaluating the Severity of Hepatic Ischemia-Reperfusion Injury.
Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1?.
Renalase Protects against Ischemic AKI.
Renalase protects the cardiomyocytes of Sprague-Dawley rats against ischemia and reperfusion injury by reducing myocardial cell necrosis and apoptosis.
Sleep Apnea Syndromes
Renalase and hypertension-demographic and clinical correlates in obstructive sleep apnea.
Sleep Apnea, Obstructive
Renalase and hypertension-demographic and clinical correlates in obstructive sleep apnea.
Sleep Bruxism
The Relationship between Sleep Bruxism Intensity and Renalase Concentration-An Enzyme Involved in Hypertension Development.
Solitary Kidney
Renalase Levels in Children with Solitary Functioning Kidney.
Starvation
Expression of the mouse ren-2 gene in the small intestine is regulated by food intake.
Stroke
An association study on renalase polymorphisms and ischemic stroke in a Chinese population.
Exercise training prevents development of cardiac contractile dysfunction in hypertensive TG (mREN-2)27 rats.
Identification of a receptor for extracellular renalase.
Load-sensitive measures may overestimate global systolic function in the presence of left ventricular hypertrophy: a comparison with load-insensitive measures.
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Renalase gene polymorphisms in patients with type 2 diabetes, hypertension and stroke.
Renalase, stroke, and hypertension in hemodialyzed patients.
Serum Renalase Levels Are Predicted by Brain-Derived Neurotrophic Factor and Associated with Cardiovascular Events and Mortality after Percutaneous Coronary Intervention.
Ureteral Obstruction
Renalase contributes to protection against renal fibrosis via inhibiting oxidative stress in rats.
Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways.
Ventricular Dysfunction
A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study.
Whooping Cough
Nifedipine-sensitive blood pressure component in hypertensive models characterized by high activity of either sympathetic nervous system or renin-angiotensin system.