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Reference on EC 1.8.1.4 - dihydrolipoyl dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bosma, H.J.; de Kok, A.; Westphal, A.H.; Veeger, C.
The composition of the pyruvate dehydrogenase complex from Azotobacter vinelandii. Does a unifying model exist for the complexes from gram-negative bacteria?
Eur. J. Biochem.
142
541-549
1984
Azotobacter vinelandii
Manually annotated by BRENDA team
Hodgson, J.A.; Lowe, P.N.; Perham, R.N.
Wild-type and mutant forms of the pyruvate dehydrogenase multienzyme complex from Bacillus subtilis
Biochem. J.
211
463-472
1983
Bacillus subtilis
Manually annotated by BRENDA team
Seckler, R.; Binder, R.; Bisswanger, H.
Purification and properties of the pyruvate dehydrogenase complex from Salmonella typhimurium and formation of hybrids with the enzyme complex from Escherichia coli
Biochim. Biophys. Acta
705
210-217
1982
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Reed, L.J.; Willms, C.R.
Purification and resolution of the pyruvate dehydrogenase complex (Escherichia coli)
Methods Enzymol.
9
247-265
1966
Escherichia coli
-
Manually annotated by BRENDA team
Sokatch, J.R.
Purification of branched-chain keto acid dehydrogenase and lipoamide dehydrogenase-valine from Pseudomonas
Methods Enzymol.
166
342-350
1988
Pseudomonas aeruginosa, Pseudomonas putida, Pseudomonas putida PpG2
Manually annotated by BRENDA team
Ono, K.; Hakozaki, M.; Kimura, A.; Kochi, H.
Purification, resolution, and reconstitution of rat liver branched-chain alpha-keto acid dehydrogenase complex
J. Biochem.
101
19-27
1987
Rattus norvegicus
Manually annotated by BRENDA team
Sundquist, A.R.; Fahey, R.C.
The novel disulfide reductase bis-gamma-glutamylcystine reductase and dihydrolipoamide dehydrogenase from Halobacterium halobium: Purification by immobilized-metal-ion affinity chromatography and properties of the enzymes
J. Bacteriol.
170
3459-3467
1988
Halobacterium salinarum
Manually annotated by BRENDA team
Lohrer, H.; Krauth-Siegel, R.L.
Purification and characterization of lipoamide dehydrogenase from Trypanosoma cruzi
Eur. J. Biochem.
194
863-869
1990
Trypanosoma cruzi
Manually annotated by BRENDA team
Borges, A.; Hawkins, C.F.; Packman, L.C.; Perham, R.N.
Cloning and sequence analysis of the genes encoding the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus
Eur. J. Biochem.
194
95-102
1990
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Dietrichs, D.; Andreesen, J.R.
Purification and comparative studies of dihydrolipoamide dehydrogenases from the anaerobic, glycine-utilizing bacteria Peptostreptococcus glycinophilus, Clostridium cylindrosporum, and Clostridium sporogenes
J. Bacteriol.
172
243-251
1990
Clostridium cylindrosporum, Peptostreptococcus glycinophilus
Manually annotated by BRENDA team
Jackman, S.A.; Hough, D.W.; Danson, M.J.; Stevenson, K.J.; Opperdoes, F.R.
Subcellular localisation of dihydrolipoamide dehydrogenase and detection of lipoic acid in bloodstream forms of Trypanosoma brucei
Eur. J. Biochem.
193
91-95
1990
Trypanosoma brucei
Manually annotated by BRENDA team
Richarme, G.
Purification of a new dihydrolipoamide dehydrogenase from Escherichia coli
J. Bacteriol.
171
6580-6585
1989
Escherichia coli
Manually annotated by BRENDA team
Perham, R.N.; Lowe, P.N.
Isolation and properties of the branched-chain 2-keto acid and pyruvate dehydrogenase multienzyme complex from Bacillus subtilis
Methods Enzymol.
166
330-342
1988
Bacillus subtilis
Manually annotated by BRENDA team
Toyoda, T.; Kobayashi, R.; Sekiguchi, T.; Koike, K.; Koike, M.; Takenaka, A.
Crystallization and preliminary X-ray analysis of pig E3, lipoamide dehydrogenase
Acta Crystallogr. Sect. D
54
982-985
1998
Peptoclostridium acidaminophilum, Sus scrofa
Manually annotated by BRENDA team
Toyoda, T.; Suzuki, K.; Sekiguchi, T.; Reed, L.J.; Takenaka, A.
Crystal structure of eucaryotic E3, lipoamide dehydrogenase from yeast
J. Biochem.
123
668-674
1998
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Carothers, D.J.; Pons, G.; Patel, M.S.
Dihydrolipoamide dehydrogenase: functional similarities and divergent evolution of the pyridine nucleotide-disulfide oxidoreductases
Arch. Biochem. Biophys.
268
409-425
1989
Azotobacter vinelandii, Ascaris suum, Geobacillus stearothermophilus, Bacillus subtilis, Bos taurus, Saccharomyces cerevisiae, Escherichia coli, Halobacterium salinarum, Homo sapiens, Pisum sativum, Pseudomonas aeruginosa, Pseudomonas putida, Rattus norvegicus, Saccharomyces pastorianus, Sus scrofa
Manually annotated by BRENDA team
Mattevi, A.; Obmolova, G.; Kalk, K.H.; van Berkel, W.J.; Hol, W.G.
Three-dimensional structure of lipoamide dehydrogenase from Pseudomonas fluorescens at 2.8 A resolution. Analysis of redox and thermostability properties
J. Mol. Biol.
230
1200-1215
1993
Azotobacter vinelandii, Pseudomonas fluorescens
Manually annotated by BRENDA team
Smith, L.D.; Bungard, S.J.; Danson, M.J.; Hough, D.W.
Dihydrolipoamide dehydrogenase from the Thermoacidophilic archaebacterium Thermoplasma acidophilum
Biochem. Soc. Trans.
15
1097
1987
Thermoplasma acidophilum
-
Manually annotated by BRENDA team
Roy, D.J.; Dawes, I.W.
Cloning and characterization of the gene encoding lipoamide dehydrogenase in Saccharomyces cerevisiae
J. Gen. Microbiol.
133
925-933
1987
Saccharomyces cerevisiae, Haloferax volcanii
Manually annotated by BRENDA team
Danson, M.J.; Conroy, K.; McQuattie, A.; Stevenson, K.J.
Dihydrolipoamide dehydrogenase from Trypanosoma brucei. Characterization and cellular location
Biochem. J.
243
661-665
1987
Trypanosoma cruzi
Manually annotated by BRENDA team
Danson, M.J.; McQuattie, A.; Stevenson, K.J.
Dihydrolipoamide dehydrogenase from halophilic archaebacteria: purification and properties of the enzyme from Halobacterium halobium
Biochemistry
25
3880-3884
1986
Halobacterium salinarum
-
Manually annotated by BRENDA team
Delaney, R.; Burns, G.; Sokatch, J.R.
Relationship of lipoamide dehydrogenases from Pseudomonas putida to other FAD-linked dehydrogenases
FEBS Lett.
168
265-270
1984
Pseudomonas putida
Manually annotated by BRENDA team
Danson, M.J.; Eisenthal, R.; Hall, S.; Kessell, S.R.; Williams, D.L.
Dihydrolipoamide dehydrogenase from halophilic archaebacteria
Biochem. J.
218
811-818
1984
Halobacterium salinarum, Haloferax volcanii, Natronobacterium gregoryi, Natronomonas pharaonis, Natronococcus occultus
Manually annotated by BRENDA team
Tsai, C.S.; Wand, A.J.; Templeton, D.M.; Weiss, P.M.
Multifunctionality of lipoamide dehydrogenase promotion of electron transferase reaction
Arch. Biochem. Biophys.
225
554-561
1983
Sus scrofa
Manually annotated by BRENDA team
Heinrich, P.; Ronft, H.; Schartau, W.; Kresze, G.B.
Lipoamide dehydrogenase from bakers yeast. Improved purification and some molecular, kinetic, and immunochemical properties
Hoppe-Seyler's Z. Physiol. Chem.
364
41-50
1983
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Matuda, S.; Saheki, T.
Intracellular distribution and biosynthesis of lipoamide dehydrogenase in rat liver
J. Biochem.
91
553-561
1982
Rattus norvegicus
Manually annotated by BRENDA team
Adamson, S.R.; Stevenson, K.J.
Inhibition of pyruvate dehydrogenase multienzyme complex from Escherichia coli with a bifunctional arsenoxide: selective inactivation of lipoamide dehydrogenase
Biochemistry
20
3420-3424
1981
Escherichia coli
-
Manually annotated by BRENDA team
Schmincke-Ott, E.; Bisswanger, H.
Dihydrolipoamide dehydrogenase component of the pyruvate dehydrogenase complex from Escherichia coli K12. Comparative characterization of the free and the complex-bound component
Eur. J. Biochem.
114
413-420
1981
Escherichia coli
Manually annotated by BRENDA team
Hopkins, N.; Williams, C.H., Jr.
Characterization of lipoamide dehydrogenase from Escherichia coli lacking the redox active disulfide: C44S and C49S
Biochemistry
34
11757-11765
1995
Escherichia coli
Manually annotated by BRENDA team
McKay, D.J.; Stevenson, K.J.
Lipoamide dehydrogenase from Malbranchea pulchella: isolation and characterization
Biochemistry
18
4702-4707
1979
Malbranchea pulchella
Manually annotated by BRENDA team
Komuniecki, R.; Saz, H.J.
Purification of lipoamide dehydrogenase from Ascaris muscle mitochondria and its relationship to NADH:NAD+ transhydrogenase activity
Arch. Biochem. Biophys.
196
239-247
1979
Ascaris suum
Manually annotated by BRENDA team
Maeda-Yorita, K.; Russell, G.C.; Guest, J.R.; Massey, V.; Williams, C.H., Jr.
Modulation of the Oxidation-Reduction Potential of the Flavin in Lipoamide Dehydrogenase from Escherichia coli by Alteration of a Nearby Charged Residue, K53R
Biochemistry
33
6213-6220
1994
Escherichia coli
Manually annotated by BRENDA team
Williams, C.H.
Flavin-containing dehydrogenases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
13
89-173
1976
Azotobacter vinelandii, Azotobacter agilis, Bacillus subtilis, Leuconostoc mesenteroides, Bos taurus, Brassica oleracea, Saccharomyces cerevisiae, Pichia kudriavzevii, Escherichia coli, Enterococcus faecalis, Homo sapiens, Mycobacterium tuberculosis, Neurospora crassa, Parvimonas micra, Phytophthora erythroseptica, Proteus vulgaris, Pseudomonas fluorescens, Globisporangium ultimum, Rattus norvegicus, Serratia marcescens, Spinacia oleracea, Squalus acanthias, Sus scrofa, Escherichia coli B / ATCC 11303, Escherichia coli Crookes, Escherichia coli M191-6
-
Manually annotated by BRENDA team
Conner, M.; Krell, T.; Lindsay, J.G.
Identification and purification of a distinct dihydrolipoamide dehydrogenase from pea chloroplasts
Planta
200
195-202
1996
Escherichia coli, Pisum sativum
Manually annotated by BRENDA team
Wais, U.; Gillmann, U.; Ulrich, J.
solation and characterization of pyruvate dehydrogenase complex from brewer's yeast
Hoppe-Seyler's Z. Physiol. Chem.
354
1378-1388
1973
Saccharomyces pastorianus
Manually annotated by BRENDA team
Scouten, W.H.; Torok, F.; Gitomer, W.
Purification of lipoamide dehydrogenase by affinity chromatography on propyllipoamide-glass columns
Biochim. Biophys. Acta
309
521-524
1973
Saccharomyces cerevisiae, Sus scrofa
Manually annotated by BRENDA team
Kawahara, Y.; Misaka, E.; Nakanishi, K.
Purification and properties of lipoamide dehydrogenase from yeast, Candida krusei
J. Biochem.
63
77-82
1963
Pichia kudriavzevii
Manually annotated by BRENDA team
Scouten, W.H.; McManus, I.R.
Microbial lipoamide dehydrogenase. Purification and some characteristics of the enzyme derived from selected microorganisms
Biochim. Biophys. Acta
227
248-263
1971
Azotobacter agilis, Bacillus subtilis, Saccharomyces cerevisiae, Escherichia coli, Neurospora crassa, Pseudomonas fluorescens, Serratia marcescens
Manually annotated by BRENDA team
Millard, S.A.; Kubose, A.; Gal, E.M.
Brain lipoyl dehydrogenase. Purification, properties, and inhibitors
J. Biol. Chem.
244
2511-2515
1969
Sus scrofa
Manually annotated by BRENDA team
Jacobi, G.; hlers, U.
Isolation und Eigenschaften von Liponsuredehydrogenase aus Chloroplasten
Z. Pflanzenphysiol.
58
193-206
1968
Spinacia oleracea
-
Manually annotated by BRENDA team
Moran, J.F.; Sun, Z.; Sarath, G.; Arredondo-Peter, R.; James, E.K.; Becana, M.; Klucas, R.V.
Molecular cloning, functional characterization, and subcellular localization of soybean nodule dihydrolipoamide reductase
Plant Physiol.
128
300-313
2002
Glycine max (O81413), Glycine max
Manually annotated by BRENDA team
Liu, T.C.; Korotchkina, L.G.; Hyatt, S.L.; Vettakkorumakankav, N.N.; Patel, M.S.
Spectroscopic studies of the characterization of recombinant human dihydrolipoamide dehydrogenase and its site-directed mutants
J. Biol. Chem.
270
15545-15550
1995
Homo sapiens
Manually annotated by BRENDA team
Liu, T.C.; Soo Hong, Y.; Korotchkina, L.G.; Vettakkorumakankav, N.N.; Patel, M.S.
Site-directed mutagenesis of human dihydrolipoamide dehydrogenase: role of lysine-54 and glutamate-192 in stabilizing the thiolate-FAD intermediate
Protein Expr. Purif.
16
27-39
1999
Homo sapiens
Manually annotated by BRENDA team
Smith, A.W.; Roche, H.; Trombe, M.C.; Briles, D.E.; Hakansson, A.
Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection
Mol. Microbiol.
44
431-448
2002
Streptococcus pneumoniae
Manually annotated by BRENDA team
Argyrou, A.; Blanchard, J.S.
Mycobacterium tuberculosis lipoamide dehydrogenase is encoded by Rv0462 and not by the lpdA or lpdB genes
Biochemistry
40
11353-11363
2001
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Marcinkeviciene, J.; Blanchard, J.S.
Catalytic properties of lipoamide dehydrogenase from Mycobacterium smegmatis
Arch. Biochem. Biophys.
340
168-176
1997
Mycolicibacterium smegmatis, Pisum sativum
Manually annotated by BRENDA team
Engels, A.; Kahmann, U.; Ruppel, H.G.; Pistorius, E.K.
Isolation, partial characterization and localization of a dihydrolipoamide dehydrogenase from the cyanobacterium Synechocystis PCC 6803
Biochim. Biophys. Acta
1340
33-44
1997
Synechocystis sp.
Manually annotated by BRENDA team
Youn, H.; Kwak, J.; Youn, H.D.; Hah, Y.C.; Kang, S.O.
Lipoamide dehydrogenase from Streptomyces seoulensis: biochemical and genetic properties
Biochim. Biophys. Acta
1388
405-418
1998
Streptomyces seoulensis
Manually annotated by BRENDA team
Schwinde, J.W.; Hertz, P.F.; Sahm, H.; Eikmanns, B.J.; Guyonvarch, A.
Lipoamide dehydrogenase from Corynebacterium glutamicum: molecular and physiological analysis of the lpd gene and characterization of the enzyme
Microbiology
147
2223-2231
2001
Corynebacterium glutamicum (Q8NTE1), Corynebacterium glutamicum, Corynebacterium glutamicum DSM 20300 (Q8NTE1)
Manually annotated by BRENDA team
Neuburger, M.; Polidori, A.M.; Pietre, E.; Faure, M.; Jourdain, A.; Bourguignon, J.; Pucci, B.; Douce, R.
Interaction between the lipoamide-containing H-protein and the lipoamide dehydrogenase (L-protein) of the glycine decarboxylase multienzyme system
Eur. J. Biochem.
267
2882-2889
2000
Pisum sativum
Manually annotated by BRENDA team
Faure, M.; Bourguignon, J.; Neuburger, M.; MacHerel, D.; Sieker, L.; Ober, R.; Kahn, R.; Cohen-Addad, C.; Douce, R.
Interaction between the lipoamide-containing H-protein and the lipoamide dehydrogenase (L-protein) of the glycine decarboxylase multienzyme system 2. Crystal structure of H- and L-proteins
Eur. J. Biochem.
267
2890-2898
2000
Pisum sativum
Manually annotated by BRENDA team
Oppermann, F.B.; Schmidt, B.; Steinbuchel, A.
Purification and characterization of acetoin:2,6-dichlorophenolindophenol oxidoreductase, dihydrolipoamide dehydrogenase, and dihydrolipoamide acetyltransferase of the Pelobacter carbinolicus acetoin dehydrogenase enzyme system
J. Bacteriol.
173
757-767
1991
Syntrophotalea carbinolica
Manually annotated by BRENDA team
McMillan, P.J.; Stimmler, L.M.; Foth, B.J.; McFadden, G.I.; Mueller, S.
The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases
Mol. Microbiol.
55
27-38
2005
Plasmodium falciparum
Manually annotated by BRENDA team
Argyrou, A.; Blanchard, J.S.; Palfey, B.A.
The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis
Biochemistry
41
14580-14590
2002
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Argyrou, A.; Sun, G.; Palfey, B.A.; Blanchard, J.S.
Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level
Biochemistry
42
2218-2228
2003
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Nordman, T.; Xia, L.; Bjorkhem-Bergman, L.; Damdimopoulos, A.; Nalvarte, I.; Arner, E.S.; Spyrou, G.; Eriksson, L.C.; Bjornstedt, M.; Olsson, J.M.
Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase
Biofactors
18
45-50
2003
Sus scrofa
Manually annotated by BRENDA team
Mitra, K.; Shivaji, S.
Novel tyrosine-phosphorylated post-pyruvate metabolic enzyme, dihydrolipoamide dehydrogenase, involved in capacitation of hamster spermatozoa
Biol. Reprod.
70
887-899
2004
Mesocricetus auratus (Q811C4)
Manually annotated by BRENDA team
Chen, H.J.; Chen, Y.M.; Chang, C.M.
Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor
Chem. Biol. Interact.
140
199-213
2002
Clostridium kluyveri, Sus scrofa
Manually annotated by BRENDA team
Wu, Y.Y.; Hsu, T.C.; Chen, T.Y.; Liu, T.C.; Liu, G.Y.; Lee, Y.J.; Tsay, G.J.
Proteinase 3 and dihydrolipoamide dehydrogenase (E3) are major autoantigens in hepatitis C virus (HCV) infection
Clin. Exp. Immunol.
128
347-352
2002
Homo sapiens
Manually annotated by BRENDA team
Xia, L.; Bjrnstedt, M.; Nordman, T.; Eriksson, L.C.; Olsson, J.M.
Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway
Eur. J. Biochem.
268
1486-1490
2001
Sus scrofa
Manually annotated by BRENDA team
Igamberdiev, A.U.; Bykova, N.V.; Ens, W.; Hill, R.D.
Dihydrolipoamide dehydrogenase from porcine heart catalyzes NADH-dependent scavenging of nitric oxide
FEBS Lett.
568
146-150
2004
Sus scrofa
Manually annotated by BRENDA team
Gutierrez-Correa, J.; Krauth-Siegel, R.L.; Stoppani, A.O.
Phenothiazine radicals inactivate Trypanosoma cruzi dihydrolipoamide dehydrogenase: enzyme protection by radical scavengers
Free Radic. Res.
37
281-291
2003
Trypanosoma cruzi
Manually annotated by BRENDA team
Kim, H.
Activity of human dihydrolipoamide dehydrogenase is reduced by mutation at threonine-44 of FAD-binding region to valine
J. Biochem. Mol. Biol.
35
437-441
2002
Homo sapiens
Manually annotated by BRENDA team
Kim, H.
Asparagine-473 residue is important to the efficient function of human dihydrolipoamide dehydrogenase
J. Biochem. Mol. Biol.
38
248-252
2005
Homo sapiens
Manually annotated by BRENDA team
Gazaryan, I.G.; Krasnikov, B.F.; Ashby, G.A.; Thorneley, R.N.; Kristal, B.S.; Brown, A.M.
Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase
J. Biol. Chem.
277
10064-10072
2002
Sus scrofa
Manually annotated by BRENDA team
Mitra, K.; Rangaraj, N.; Shivaji, S.
Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: Correlation of its localization, tyrosine phosphorylation and activity during sperm capacitation
J. Biol. Chem.
280
25743-25753
2005
Mesocricetus auratus
Manually annotated by BRENDA team
Hiromasa, Y.; Meno, K.; Aso, Y.
Denaturation of the Bacillus stearothermophilus dihydrolipoamide dehydrogenase in the presence of guanidine-HCl at low temperature
J. Fac. Agric. Kyushu Univ.
47
387-394
2003
Geobacillus stearothermophilus
-
Manually annotated by BRENDA team
Bjoernstedt, M.; Nordman, T.; Olsson, J.M.
Extramitochondrial reduction of ubiquinone by flavoenzymes
Methods Enzymol.
378
131-138
2004
Sus scrofa
Manually annotated by BRENDA team
Ivanova, P.; Harizanova, N.; Krasteva, M.; Dimov, S.V.; Ralchev, K.
Drosophila dihydrolipoamide dehydrogenase. Protein structure. Developmental expression
Biokhimiya, Biofizika, Molekulyarnaya Biologiya i Genetika, Mikrobiologiya i Fiziologiya
96
115-123
2005
Drosophila melanogaster, Drosophila virilis
-
Manually annotated by BRENDA team
Kim, H.
Examination of the importance of Pro-453 in human dihydrolipoamide dehydrogenase predicted from the three-dimensional structure
Bull. Korean Chem. Soc.
27
819-820
2006
Homo sapiens
-
Manually annotated by BRENDA team
Gutierrez-Correa, J.
Trypanosoma cruzi dihydrolipoamide dehydrogenase as target for phenothiazine cationic radicals. Effect of antioxidants
Curr. Drug Targets
7
1155-1179
2006
Trypanosoma cruzi
Manually annotated by BRENDA team
Tahara, E.B.; Barros, M.H.; Oliveira, G.A.; Netto, L.E.; Kowaltowski, A.J.
Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging
FASEB J.
21
274-283
2007
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Odievre, M.H.; Chretien, D.; Munnich, A.; Robinson, B.H.; Dumoulin, R.; Masmoudi, S.; Kadhom, N.; Roetig, A.; Rustin, P.; Bonnefont, J.P.
A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency
Hum. Mutat.
25
323-324
2005
Homo sapiens
Manually annotated by BRENDA team
Hudson, P.; Gorton, T.S.; Papazisi, L.; Cecchini, K.; Frasca, S.; Geary, S.J.
Identification of a virulence-associated determinant, dihydrolipoamide dehydrogenase (lpd), in Mycoplasma gallisepticum through in vivo screening of transposon mutants
Infect. Immun.
74
931-939
2006
Mycoplasma gallisepticum
Manually annotated by BRENDA team
Nishimoto, E.; Aso, Y.; Koga, T.; Yamashita, S.
Thermal unfolding process of dihydrolipoamide dehydrogenase studied by fluorescence spectroscopy
J. Biochem.
140
349-357
2006
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Kim, H.
Activity of human dihydrolipoamide dehydrogenase is largely reduced by mutation at isoleucine-51 to alanine
J. Biochem. Mol. Biol.
39
223-227
2006
Homo sapiens
Manually annotated by BRENDA team
Klyachko, N.L.; Shchedrina, V.A.; Efimov, A.V.; Kazakov, S.V.; Gazaryan, I.G.; Kristal, B.S.; Brown, A.M.
pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification
J. Biol. Chem.
280
16106-16114
2005
Sus scrofa (P09623), Sus scrofa
Manually annotated by BRENDA team
Rajashankar, K.R.; Bryk, R.; Kniewel, R.; Buglino, J.A.; Nathan, C.F.; Lima, C.D.
Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis
J. Biol. Chem.
280
33977-33983
2005
Mycobacterium tuberculosis (P9WHH9), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WHH9)
Manually annotated by BRENDA team
Ciszak, E.M.; Makal, A.; Hong, Y.S.; Vettaikkorumakankauv, A.K.; Korotchkina, L.G.; Patel, M.S.
How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex
J. Biol. Chem.
281
648-655
2006
Homo sapiens
Manually annotated by BRENDA team
Wang, Y.C.; Wang, S.T.; Li, C.; Liu, W.H.; Chen, P.R.; Chen, L.Y.; Liu, T.C.
The role of N286 and D320 in the reaction mechanism of human dihydrolipoamide dehydrogenase (E3) center domain
J. Biomed. Sci.
14
203-210
2007
Homo sapiens (P09622), Homo sapiens
Manually annotated by BRENDA team
Brautigam, C.A.; Chuang, J.L.; Tomchick, D.R.; Machius, M.; Chuang, D.T.
Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations
J. Mol. Biol.
350
543-552
2005
Homo sapiens
Manually annotated by BRENDA team
Brautigam, C.A.; Wynn, R.M.; Chuang, J.L.; Machius, M.; Tomchick, D.R.; Chuang, D.T.
Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complex
Structure
14
611-621
2006
Homo sapiens
Manually annotated by BRENDA team
Chakraborty, S.; Sakka, M.; Kimura, T.; Sakka, K.
Two proteins with diaphorase activity from Clostridium thermocellum and Moorella thermoacetica
Biosci. Biotechnol. Biochem.
72
877-879
2008
Acetivibrio thermocellus, Moorella thermoacetica ATCC 39073
Manually annotated by BRENDA team
Castro, M.E.; Molina, R.; Diaz, W.; Pichuantes, S.E.; Vasquez, C.C.
The dihydrolipoamide dehydrogenase of Aeromonas caviae ST exhibits NADH-dependent tellurite reductase activity
Biochem. Biophys. Res. Commun.
375
91-94
2008
Aeromonas caviae, Escherichia coli, Geobacillus stearothermophilus (P11959), Geobacillus stearothermophilus, Zymomonas mobilis (P50970), Zymomonas mobilis, Streptococcus pneumoniae (Q8VPK7), Streptococcus pneumoniae
Manually annotated by BRENDA team
Luis, P.B.; Ruiter, J.P.; Aires, C.C.; Soveral, G.; de Almeida, I.T.; Duran, M.; Wanders, R.J.; Silva, M.F.
Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation
Biochim. Biophys. Acta
1767
1126-1133
2007
Rattus norvegicus
Manually annotated by BRENDA team
Kumar, V.; Kota, V.; Shivaji, S.
Hamster sperm capacitation: Role of pyruvate dehydrogenase A and dihydrolipoamide dehydrogenase
Biol. Reprod.
79
190-199
2008
Mesocricetus auratus
Manually annotated by BRENDA team
Chakraborty, S.; Sakka, M.; Kimura, T.; Sakka, K.
Characterization of a dihydrolipoyl dehydrogenase having diaphorase activity of Clostridium kluyveri
Biosci. Biotechnol. Biochem.
72
982-988
2008
Clostridium kluyveri (A5N930), Clostridium kluyveri
Manually annotated by BRENDA team
Kim, H.
Site-specific modifications of the Cys-45 residue in human dihydrolipoamide dehydrogenase to Ser and Tyr
Bull. Korean Chem. Soc.
28
907-908
2007
Homo sapiens
-
Manually annotated by BRENDA team
Yan, L.J.; Yang, S.H.; Shu, H.; Prokai, L.; Forster, M.J.
Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE
Electrophoresis
28
1036-1045
2007
Rattus norvegicus
Manually annotated by BRENDA team
Batista, A.P.; Kletzin, A.; Pereira, M.M.
The dihydrolipoamide dehydrogenase from the crenarchaeon Acidianus ambivalens
FEMS Microbiol. Lett.
281
147-154
2008
Acidianus ambivalens (A4V929), Acidianus ambivalens
Manually annotated by BRENDA team
Kim, Y.; Ingram, L.O.; Shanmugam, K.T.
Dihydrolipoamide dehydrogenase mutation alters the NADH sensitivity of pyruvate dehydrogenase complex of Escherichia coli K-12
J. Bacteriol.
190
3851-3858
2008
Escherichia coli K-12
Manually annotated by BRENDA team
Hakansson, A.P.; Smith, A.W.
Enzymatic characterization of dihydrolipoamide dehydrogenase from Streptococcus pneumoniae harboring its own substrate
J. Biol. Chem.
282
29521-29530
2007
Streptococcus pneumoniae
Manually annotated by BRENDA team
Wang, Y.C.; Wang, S.T.; Li, C.; Chen, L.Y.; Liu, W.H.; Chen, P.R.; Chou, M.C.; Liu, T.C.
The role of amino acids T148 and R281 in human dihydrolipoamide dehydrogenase
J. Biomed. Sci.
15
37-46
2008
Homo sapiens (P09622), Homo sapiens
Manually annotated by BRENDA team
Deghmane, A.E.; Soualhine, H.; Soulhine, H.; Bach, H.; Sendide, K.; Itoh, S.; Tam, A.; Noubir, S.; Talal, A.; Lo, R.; Toyoshima, S.; Av-Gay, Y.; Hmama, Z.
Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation
J. Cell Sci.
120
2796-2806
2007
Mycobacterium tuberculosis, no activity in Mycobacterium smegmatis, Mycobacterium tuberculosis variant bovis BCG
Manually annotated by BRENDA team
Anderson, J.K.; Baker, M.; Jaffers, O.; Pearle, M.S.; Lindberg, G.L.; Cadeddu, J.A.
Time course of nicotinamide adenine dinucleotide diaphorase staining after renal radiofrequency ablation influences viability assessment
J. Endourol.
21
223-227
2007
Sus scrofa
Manually annotated by BRENDA team
Yan, L.J.; Thangthaeng, N.; Forster, M.J.
Changes in dihydrolipoamide dehydrogenase expression and activity during postnatal development and aging in the rat brain
Mech. Ageing Dev.
129
282-290
2008
Rattus norvegicus
Manually annotated by BRENDA team
Brown, A.M.; Gordon, D.; Lee, H.; Wavrant-De Vrieze, F.; Cellini, E.; Bagnoli, S.; Nacmias, B.; Sorbi, S.; Hardy, J.; Blass, J.P.
Testing for linkage and association across the dihydrolipoyl dehydrogenase gene region with Alzheimers disease in three sample populations
Neurochem. Res.
32
857-869
2007
Homo sapiens
Manually annotated by BRENDA team
Dhanasekaran, M.; Albano, C.B.; Pellet, L.; Karuppagounder, S.S.; Uthayathas, S.; Suppiramaniam, V.; Brown-Borg, H.; Ebadi, M.
Role of lipoamide dehydrogenase and metallothionein on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
Neurochem. Res.
33
980-984
2008
Mus musculus, Mus musculus C57/Bl-6
Manually annotated by BRENDA team
Babady, N.E.; Pang, Y.P.; Elpeleg, O.; Isaya, G.
Cryptic proteolytic activity of dihydrolipoamide dehydrogenase
Proc. Natl. Acad. Sci. USA
104
6158-6163
2007
Homo sapiens, Mus musculus, Sus scrofa
Manually annotated by BRENDA team
Chakraborty, S.; Sakka, M.; Kimura, T.; Sakka, K.
Cloning and expression of a Clostridium kluyveri gene responsible for diaphorase activity
Biosci. Biotechnol. Biochem.
72
735-741
2008
Clostridium kluyveri
Manually annotated by BRENDA team
de Mello, S.T.; de Miranda Neto, M.H.; Zanoni, J.N.; Furlan, M.M.
Effects of insulin treatment on HuC/HuD, NADH diaphorase, and nNOS-positive myoenteric neurons of the duodenum of adult rats with acute diabetes
Digest. Dis. Sci.
54
731-737
2009
Rattus norvegicus
Manually annotated by BRENDA team
Kikuchi, G.; Motokawa, Y.; Yoshida, T.; Hiraga, K.
Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia
Proc. Jpn. Acad. Ser. B Phys. Biol. Sci.
84
246-263
2008
no activity in Escherichia coli, Pisum sativum
Manually annotated by BRENDA team
Park, Y.H.; Patel, M.S.
Characterization of interactions of dihydrolipoamide dehydrogenase with its binding protein in the human pyruvate dehydrogenase complex
Biochem. Biophys. Res. Commun.
395
416-419
2010
Homo sapiens
Manually annotated by BRENDA team
Bryk, R.; Arango, N.; Venugopal, A.; Warren, J.D.; Park, Y.H.; Patel, M.S.; Lima, C.D.; Nathan, C.
Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase
Biochemistry
49
1616-1627
2010
Mycobacterium tuberculosis (P9WHH8), Mycobacterium tuberculosis, Mycobacterium tuberculosis CDC 1551 (P9WHH8)
Manually annotated by BRENDA team
Tyagi, T.K.; Ponnan, P.; Singh, P.; Bansal, S.; Batra, A.; Collin, F.; Guillonneau, F.; Jore, D.; Patkar, S.A.; Saxena, R.K.; Parmar, V.S.; Rastogi, R.C.; Raj, H.G.
Moonlighting protein in Starkeyomyces koorchalomoides: characterization of dihydrolipoamide dehydrogenase as a protein acetyltransferase utilizing acetoxycoumarin as the acetyl group donor
Biochimie
91
868-875
2009
Starkeyomyces koorchalomoides, Starkeyomyces koorchalomoides FDUS 0337
Manually annotated by BRENDA team
Kim, S.Y.; Kim, J.
Roles of dihydrolipoamide dehydrogenase Lpd1 in Candida albicans filamentation
Fungal Genet. Biol.
47
782-788
2010
Candida albicans, Candida albicans CAI-4
Manually annotated by BRENDA team
Stibingerova, A.; Velvarska, H.; Kynclova, K.; Marounkova, B.; Spundova, M.; Entlicher, G.
Lipoamide dehydrogenase and diaphorase catalyzed conversion of some NO donors to NO and reduction of NO scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (PTIO)
Gen. Physiol. Biophys.
28
384-390
2009
Bos taurus, Sus scrofa
Manually annotated by BRENDA team
Kurokawa, J.; Asano, M.; Nomoto, S.; Makino, Y.; Itoh, N.
Gene cloning and characterization of dihydrolipoamide dehydrogenase from Microbacterium luteolum: A useful enzymatic regeneration system of NAD+ from NADH
J. Biosci. Bioeng.
109
218-223
2010
Microbacterium luteolum (B6F1A8), Microbacterium luteolum, Microbacterium luteolum JCM 9174 (B6F1A8)
Manually annotated by BRENDA team
Chen, W.; Chi, Y.; Taylor, N.L.; Lambers, H.; Finnegan, P.M.
Disruption of ptLPD1 or ptLPD2, genes that encode isoforms of the plastidial lipoamide dehydrogenase, confers arsenate hypersensitivity in Arabidopsis
Plant Physiol.
153
1385-1397
2010
Arabidopsis thaliana
Manually annotated by BRENDA team
Ambrus, A.; Torocsik, B.; Adam-Vizi, V.
Periplasmic cold expression and one-step purification of human dihydrolipoamide dehydrogenase
Protein Expr. Purif.
63
50-57
2009
Homo sapiens (P09622), Homo sapiens
Manually annotated by BRENDA team
Ajith, V.K.; Prasad, R.
A novel protein that binds to dnrN-dnrO intergenic region of Streptomyces peucetius purified by DNA affinity capture has dihydrolipoamide dehydrogenase activity
Protein Expr. Purif.
67
132-138
2009
Streptomyces peucetius, Streptomyces peucetius 29050
Manually annotated by BRENDA team
Huo, J.; Shi, H.; Yao, Q.; Chen, H.; Wang, L.; Chen, K.
Cloning and purification of recombinant silkworm dihydrolipoamide dehydrogenase expressed in Escherichia coli
Protein Expr. Purif.
72
95-100
2010
Bombyx mori (Q8MUB0), Bombyx mori
Manually annotated by BRENDA team
Wuebbeler, J.H.; Raberg, M.; Brandt, U.; Steinbuechel, A.
Dihydrolipoamide dehydrogenases of Advenella mimigardefordensis and Ralstonia eutropha catalyze cleavage of 3,3-dithiodipropionic acid into 3-mercaptopropionic acid
Appl. Environ. Microbiol.
76
7023-7028
2010
Advenella mimigardefordensis, Cupriavidus necator (Q0KBV8), Cupriavidus necator, Advenella mimigardefordensis DPN7, Cupriavidus necator ATCC 17699 (Q0KBV8)
Manually annotated by BRENDA team
Kim, H.
Characterization of two site-specific mutations in human dihydrolipoamide dehydrogenase
Bull. Korean Chem. Soc.
34
1621-1622
2013
Homo sapiens
-
Manually annotated by BRENDA team
Venugopal, A.; Bryk, R.; Shi, S.; Rhee, K.; Rath, P.; Schnappinger, D.; Ehrt, S.; Nathan, C.
Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes
Cell Host Microbe
9
21-31
2011
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Yan, L.J.; Sumien, N.; Thangthaeng, N.; Forster, M.J.
Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide
Free Radic. Res.
47
123-133
2013
Rattus norvegicus
Manually annotated by BRENDA team
Tyx, R.E.; Roche-Hakansson, H.; Hakansson, A.P.
Role of dihydrolipoamide dehydrogenase in regulation of raffinose transport in Streptococcus pneumoniae
J. Bacteriol.
193
3512-3524
2011
Streptococcus pneumoniae
Manually annotated by BRENDA team
Yan, L.J.; Thangthaeng, N.; Sumien, N.; Forster, M.J.
Serum dihydrolipoamide dehydrogenase is a labile enzyme
J. Biochem. Pharmacol. Res.
1
30-42
2013
Rattus norvegicus
Manually annotated by BRENDA team
Hallstroem, T.; Moergelin, M.; Barthel, D.; Raguse, M.; Kunert, A.; Hoffmann, R.; Skerka, C.; Zipfel, P.F.
Dihydrolipoamide dehydrogenase of Pseudomonas aeruginosa is a surface-exposed immune evasion protein that binds three members of the factor H family and plasminogen
J. Immunol.
189
4939-4950
2012
Pseudomonas aeruginosa (Q9I3D1), Pseudomonas aeruginosa, Pseudomonas aeruginosa ATCC 15692 (Q9I3D1)
Manually annotated by BRENDA team
Roldan, A.; Comini, M.A.; Crispo, M.; Krauth-Siegel, R.L.
Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei
Mol. Microbiol.
81
623-639
2011
Trypanosoma brucei
Manually annotated by BRENDA team
Connaris, H.; Chaudhuri, J.B.; Danson, M.J.; Hough, D.W.
Expression, reactivation, and purification of enzymes from Haloferax volcanii in Escherichia coli.
Biotechnol. Bioeng.
64
38-45
1999
Haloferax volcanii (Q04829), Haloferax volcanii, Haloferax volcanii DSM 3757 (Q04829)
Manually annotated by BRENDA team
Jolley, K.A.; Russell, R.J.; Hough, D.W.; Danson, M.J.
Site-directed mutagenesis and halophilicity of dihydrolipoamide dehydrogenase from the halophilic archaeon, Haloferax volcanii
Eur. J. Biochem.
248
362-368
1997
Haloferax volcanii (Q04829), Haloferax volcanii, Haloferax volcanii DSM 3757 (Q04829)
Manually annotated by BRENDA team
Jolley, K.A.; Rapaport, E.; Hough, D.W.; Danson, M.J.; Woods, W.G.; Dyall-Smith, M.L.
Dihydrolipoamide dehydrogenase from the halophilic archaeon Haloferax volcanii: homologous overexpression of the cloned gene
J. Bacteriol.
178
3044-3048
1996
Haloferax volcanii (Q04829), Haloferax volcanii, Haloferax volcanii DSM 3757 (Q04829)
Manually annotated by BRENDA team
Maheshwari, R.; Bharadwaj, G.; Bhat, M.K.
Thermophilic fungi: their physiology and enzymes
Microbiol. Mol. Biol. Rev.
64
461-488
2000
Malbranchea pulchella
Manually annotated by BRENDA team
Kianmehr, A.; Mahdizadeh, R.; Oladnabi, M.; Ansari, J.
Recombinant expression, characterization and application of a dihydrolipoamide dehydrogenase with diaphorase activity from Bacillus sphaericus
3 Biotech
7
153
2017
Lysinibacillus sphaericus, Lysinibacillus sphaericus PAD-91
Manually annotated by BRENDA team
Ambrus, A.; Adam-Vizi, V.
Molecular dynamics study of the structural basis of dysfunction and the modulation of reactive oxygen species generation by pathogenic mutants of human dihydrolipoamide dehydrogenase
Arch. Biochem. Biophys.
538
145-155
2013
Homo sapiens
Manually annotated by BRENDA team
Ambrus, A.; Mizsei, R.; Adam-Vizi, V.
Structural alterations by five disease-causing mutations in the low-pH conformation of human dihydrolipoamide dehydrogenase (hLADH) analyzed by molecular dynamics - implications in functional loss and modulation of reactive oxygen species generation by pa
Biochem. Biophys. Rep.
2
50-56
2015
Homo sapiens (P09622), Homo sapiens
Manually annotated by BRENDA team
Ambrus, A.; Wang, J.; Mizsei, R.; Zambo, Z.; Torocsik, B.; Jordan, F.; Adam-Vizi, V.
Structural alterations induced by ten disease-causing mutations of human dihydrolipoamide dehydrogenase analyzed by hydrogen/deuterium-exchange mass spectrometry implications for the structural basis of E3 deficiency
Biochim. Biophys. Acta
1862
2098-2109
2016
Homo sapiens (P09622), Homo sapiens
Manually annotated by BRENDA team
Moxley, M.A.; Beard, D.A.; Bazil, J.N.
A pH-dependent kinetic model of dihydrolipoamide dehydrogenase from multiple organisms
Biophys. J.
107
2993-3007
2014
Escherichia coli (P0A9P0), Escherichia coli, Homo sapiens (P09622), Homo sapiens, Spinacia oleracea (A0A0K9R8G5), Spinacia oleracea
Manually annotated by BRENDA team
Laine, L.M.; Biddau, M.; Byron, O.; Mueller, S.
Biochemical and structural characterization of the apicoplast dihydrolipoamide dehydrogenase of Plasmodium falciparum
Biosci. Rep.
35
e00171
2015
Plasmodium falciparum
Manually annotated by BRENDA team
Kim, H.
Characterization of site-specific human dihydrolipoamide dehydrogenase mutant with a switched kinetic mechanism
Bull. Korean Chem. Soc.
35
1603-1604
2014
Homo sapiens (P09622)
-
Manually annotated by BRENDA team
Dadinova, L.; Rodina, E.; Vorobyeva, N.; Kurilova, S.; Nazarova, T.; Shtykova, E.
Structural investigations of E. coli dihydrolipoamide dehydrogenase in solution small-angle X-ray scattering and molecular docking
Crystallogr. Rep.
61
414-420
2016
Escherichia coli
-
Manually annotated by BRENDA team
Glasser, N.R.; Wang, B.X.; Hoy, J.A.; Newman, D.K.
The pyruvate and alpha-ketoglutarate dehydrogenase complexes of Pseudomonas aeruginosa catalyze pyocyanin and phenazine-1-carboxylic acid reduction via the subunit dihydrolipoamide dehydrogenase
J. Biol. Chem.
292
5593-5607
2017
Pseudomonas aeruginosa (A0A0H2Z9F5), Pseudomonas aeruginosa (A0A0H2ZB32), Pseudomonas aeruginosa (A0A0H2ZHZ0), Pseudomonas aeruginosa UCBPP-PA14 (A0A0H2Z9F5), Pseudomonas aeruginosa UCBPP-PA14 (A0A0H2ZB32), Pseudomonas aeruginosa UCBPP-PA14 (A0A0H2ZHZ0)
Manually annotated by BRENDA team
Fukamichi, T.; Nishimoto, E.
Conformational change near the redox center of dihydrolipoamide dehydrogenase induced by NAD+ to regulate the enzyme activity
J. Fluoresc.
25
577-583
2015
Geobacillus stearothermophilus (P11959)
Manually annotated by BRENDA team
Kim, H.
Characterization of site-specific mutations affecting the catalytic efficiency of human dihydrolipoamide dehydrogenase toward NAD+
J. Korean Chem. Soc.
59
183-187
2015
Homo sapiens (P09622)
-
Manually annotated by BRENDA team
Kim, H.
Characterization of site-specific mutations in human dihydrolipoamide dehydrogenase significantly destabilizing the transition state of the enzyme catalysis
J. Korean Chem. Soc.
59
344-348
2015
Homo sapiens (P09622)
-
Manually annotated by BRENDA team
Kim, H.
Characterization of human dihydrolipoamide dehydrogenase mutant with significantly decreased catalytic power
J. Korean Chem. Soc.
60
378-382
2016
Homo sapiens (P09622)
-
Manually annotated by BRENDA team
Dayan, A.; Babin, G.; Ganoth, A.; Kayouf, N.S.; Nitoker Eliaz, N.; Mukkala, S.; Tsfadia, Y.; Fleminger, G.
The involvement of coordinative interactions in the binding of dihydrolipoamide dehydrogenase to titanium dioxide-Localization of a putative binding site
J. Mol. Recognit.
30
e2617
2017
Rhodococcus ruber, Homo sapiens (P09622), Homo sapiens, Rhodococcus ruber GIN1
Manually annotated by BRENDA team
Chen, W.; Taylor, N.L.; Chi, Y.; Millar, A.H.; Lambers, H.; Finnegan, P.M.
The metabolic acclimation of Arabidopsis thaliana to arsenate is sensitized by the loss of mitochondrial lipoamide dehydrogenase2, a key enzyme in oxidative metabolism
Plant Cell Environ.
37
684-695
2014
Arabidopsis thaliana (Q9M5K2), Arabidopsis thaliana
Manually annotated by BRENDA team
Way, L.; Faktor, J.; Dvorakova, P.; Nicholson, J.; Vojtesek, B.; Graham, D.; Ball, K.L.; Hupp, T.
Rearrangement of mitochondrial pyruvate dehydrogenase subunit dihydrolipoamide dehydrogenase protein-protein interactions by the MDM2 ligand nutlin-3
Proteomics
16
2327-2344
2016
Homo sapiens (P09622)
Manually annotated by BRENDA team
Park, Y.H.; Patel, M.S.
Characterization of interactions of dihydrolipoamide dehydrogenase with its binding protein in the human pyruvate dehydrogenase complex
Biochem. Biophys. Res. Commun.
395
416-419
2010
Homo sapiens (P09622), Homo sapiens
Manually annotated by BRENDA team
Yang, X.; Song, J.; Yan, L.J.
Chronic inhibition of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as an approach to managing diabetic oxidative stress
Antioxidants (Basel)
8
32
2019
Homo sapiens (P09622)
Manually annotated by BRENDA team
Szabo, E.; Mizsei, R.; Wilk, P.; Zambo, Z.; Torocsik, B.; Weiss, M.S.; Adam-Vizi, V.; Ambrus, A.
Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase
Free Radic. Biol. Med.
124
214-220
2018
Homo sapiens
Manually annotated by BRENDA team
Chiranjivi, A.K.; Dubey, V.K.
Dihydrolipoamide dehydrogenase from Leishmania donovani New insights through biochemical characterization
Int. J. Biol. Macromol.
112
1241-1247
2018
Leishmania donovani, Leishmania donovani BHU1081
Manually annotated by BRENDA team
Chiranjivi, A.K.; Prakash, J.; Saha, G.; Chandra, P.; Dubey, V.K.
Mutational studies on Leishmania donovani dihydrolipoamide dehydrogenase (LdBPK291950.1) indicates that the enzyme may not be classical class-I pyridine nucleotide-disulfide oxidoreductase
Int. J. Biol. Macromol.
164
2141-2150
2020
Leishmania donovani
Manually annotated by BRENDA team
Dayan, A.; Lamed, R.; Benayahu, D.; Fleminger, G.
RGD-modified dihydrolipoamide dehydrogenase as a molecular bridge for enhancing the adhesion of bone forming cells to titanium dioxide implant surfaces
J. Biomed. Mater. Res. A
107
545-551
2019
Homo sapiens
Manually annotated by BRENDA team
Kim, H.
Characterization of two site-specific mutations in human dihydrolipoamide dehydrogenase deteriorating the apparent enzyme binding affinities to both dihydrolipoamide and NAD+
J. Korean Chem. Soc.
62
253-256
2018
Homo sapiens (P09622)
-
Manually annotated by BRENDA team
Kim, H.
Characterization of human dihydrolipoamide dehydrogenase mutant showing significantly decreased catalytic efficiency
J. Korean Chem. Soc.
63
134-137
2019
Homo sapiens (P09622)
-
Manually annotated by BRENDA team
Kim, H.
Characterization of a human dihydrolipoamide dehydrogenase mutant showing significantly decreased catalytic efficiency toward NAD+
J. Korean Chem. Soc.
64
141-144
2020
Homo sapiens (P09622)
-
Manually annotated by BRENDA team
Kim, H.
Characterization of a site-specifically modified human dihydrolipoamide dehydrogenase mutant showing significantly changed kinetic properties
J. Korean Chem. Soc.
65
83-87
2021
Homo sapiens (P09622)
-
Manually annotated by BRENDA team
Dayan, A.; Yeheskel, A.; Lamed, R.; Fleminger, G.; Ashur-Fabian, O.
Dihydrolipoamide dehydrogenase moonlighting activity as a DNA chelating agent
Proteins
89
21-28
2020
Homo sapiens (P09622)
Manually annotated by BRENDA team
Shin, D.; Lee, J.; You, J.H.; Kim, D.; Roh, J.L.
Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer
Redox Biol.
30
101418
2020
Homo sapiens
Manually annotated by BRENDA team
Dai, F.; Zhang, W.; Zhuang, Q.; Shao, Y.; Zhao, X.; Lv, Z.; Li, C.
Dihydrolipoamide dehydrogenase of Vibrio splendidus is involved in adhesion to Apostichopus japonicus
Virulence
10
839-848
2019
Vibrio splendidus, Vibrio splendidus LGP32
Manually annotated by BRENDA team