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Information on EC 1.8.5.9 - protein dithiol:quinone oxidoreductase DsbB

for references in articles please use BRENDA:EC1.8.5.9

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IUBMB Comments

DsbB is a protein found in Gram-negative bacteria that functions within a pathway for protein disulfide bond formation. The enzyme catalyses the oxidation of the DsbA protein by generating disulfide bonds de novo via the reduction of membrane quinones. cf. EC 1.8.4.15, protein dithiol oxidoreductase (disulfide-forming)

The enzyme appears in viruses and cellular organisms
Reaction Schemes
hide(Overall reactions are displayed. Show all >>)
a [DsbA protein] with reduced L-cysteine residues
+
=
a [DsbA protein] carrying a disulfide bond
+

Synonyms
ctdsbb, vkor homolog, disulfide bond formation protein b, disulfide bond protein b, disulfide-bond formation protein b, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a [DsbA protein] with reduced L-cysteine residues + a quinone = a [DsbA protein] carrying a disulfide bond + a quinol
show the reaction diagram
overall reaction
-
-
-
a [DsbA protein] with reduced L-cysteine residues + a [DsbB protein] carrying a disulfide bond = a [DsbA protein] carrying a disulfide bond + a [DsbB protein] with reduced L-cysteine residues
show the reaction diagram
(1a)
-
-
-
a [DsbB protein] with reduced L-cysteine residues + a quinone = a [DsbB protein] carrying a disulfide bond + a quinol
show the reaction diagram
(1b)
-
-
-
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